The development of tone discrimination in infancy: Evidence from a cross-linguistic, multi-lab report.

We report the findings of a multi-language and multi-lab investigation of young infants' ability to discriminate lexical tones as a function of their native language, age and language experience, as well as of tone properties. Given the high prevalence of lexical tones across human languages, understanding lexical tone acquisition is fundamental for comprehensive theories of language learning. While there are some similarities between the developmental course of lexical tone perception and that of vowels and consonants, findings for lexical tones tend to vary greatly across different laboratories. To reconcile these differences and to assess the developmental trajectory of native and non-native perception of tone contrasts, this study employed a single experimental paradigm with the same two pairs of Cantonese tone contrasts (perceptually similar vs. distinct) across 13 laboratories in Asia-Pacific, Europe and North-America testing 5-, 10- and 17-month-old monolingual (tone, pitch-accent, non-tone) and bilingual (tone/non-tone, non-tone/non-tone) infants. Across the age range and language backgrounds, infants who were not exposed to Cantonese showed robust discrimination of the two non-native lexical tone contrasts. Contrary to this overall finding, the statistical model assessing native discrimination by Cantonese-learning infants failed to yield significant effects. These findings indicate that lexical tone sensitivity is maintained from 5 to 17 months in infants acquiring tone and non-tone languages, challenging the generalisability of the existing theoretical accounts of perceptual narrowing in the first months of life. RESEARCH HIGHLIGHTS: This is a multi-language and multi-lab investigation of young infants' ability to discriminate lexical tones. This study included data from 13 laboratories testing 5-, 10-, and 17-month-old monolingual (tone, pitch-accent, non-tone) and bilingual (tone/non-tone, non-tone/non-tone) infants. Overall, infants discriminated a perceptually similar and a distinct non-native tone contrast, although there was no evidence of a native tone-language advantage in discrimination. These results demonstrate maintenance of tone discrimination throughout development.

Deeper Defluorination and Mineralization of a Novel PFECA (C7 HFPO-TA) in Vacuum UV/Sulfite: Unique Mechanism of H/OCF3 Exchange.

C7 HFPO-TA is a newly identified alternative to PFOA, which possesses a unique structure fragment (CF3O-CF(CF3)-). In this study, we evaluated the chemical reactivity of C7 HFPO-TA in advanced oxidation and reduction processes for the first time, which revealed a series of unexpected transformation mechanisms. The results showed that reductive degradation based on hydrated electrons (eaq-) was more feasible for the degradation of C7 HFPO-TA. For oxidative degradation, the branched -CF3 at the α-position carbon posed as the spatial hindrance, shielding the attack of SO4•- to -COO-. The synergistic effects of HO•/eaq- and direct photolysis led to deeper defluorination and mineralization of C7 HFPO-TA in the vacuum UV/sulfite (VUV/SF) process. We identified a unique H/OCF3 exchange that converted the CF3O-CF(CF3)- into H-CF(CF3)- directly, and the SO3•- involved mechanism of C7 HFPO-TA for the first time. We revealed the branched -CF3 connected to the same carbon next to the CF3O- group affected the C-O bond cleavage site, preferring the H/OCF3 exchange pathway. The defluorination of C7 HFPO-TA was compared with PFOA and three PFECAs in the VUV/SF process, which was highly dependent on structures. Degradation kinetics, theoretical calculations, and products' analysis provided an in-depth perspective on the degradation mechanisms and pathways of C7 HFPO-TA.

Overall study of solar simulation optical system with large irradiated surface using free-form concentrator to improve uniformity.

Large irradiation surface solar simulator often has the problem of low irradiation uniformity. Therefore, a method for designing a large irradiation surface solar simulator with high irradiation uniformity is proposed. According to the law of conservation of energy and the edge-ray principle of non-imaging optics, the free-form surface concentrator is designed and optimized by using the simulated annealing algorithm based on Bessel curve to improve the incident beam uniformity of the integrator. The optical integrator and projection system are also designed and optimized to eliminate aberrations, improve light efficiency, and enlarge the irradiation area. The design is verified using LightTools software and achieves an effective irradiation size of Φ1200 mm with an irradiance of a solar constant and an irradiation uniformity of less than 2.0%. This study provides accurate and reliable solar irradiation for laboratory calibration and performance testing of spacecraft payloads.

Impact of LEAP and CBT-AN Therapy on Improving Outcomes in Women with Anorexia Nervosa.

Anorexia nervosa (AN) is a mental health disorder that has serious physical, emotional and social consequences. Whilst cognitive behavioural therapy for AN (CBT-AN) has demonstrated efficacy, there remains a global need to improve AN treatment. Compulsive exercise activity therapy (LEAP) is an active therapy consisting of the addition to CBT-AN of eight specific sessions that focus on exercise and motivation for behavioural change. This paper presents a secondary analysis of 74 female participants in a randomised control trial of LEAP plus CBT-AN versus CBT-AN alone. The main aim of this study was to explore putative predictors and to estimate the magnitude of changes due to LEAP for specific outcome measures. Participants (LEAP: n = 36; CBT-AN: n = 38) were assessed at three successive surveys: baseline, end of therapy, and 6 months post-therapy. The overall effect sizes for changes between baseline to end of therapy and baseline to 6-month follow-up assessment showed large effect sizes (Cohen's d > = 0.80) for mental-health-related quality of life (MHRQoL), weight concern, dietary restraint, eating concern, AN stage change, and psychological distress (all p < 0.05). The results also indicated that several pre-treatment characteristics, including body mass index (BMI), level of eating disorder (ED) symptoms, and MHRQoL are important for identifying whether a treatment is likely to be effective. Future treatment programs should aim to optimise early improvements in BMI, ED symptoms, and MHRQoL.

Target and non-target analysis of per- and polyfluoroalkyl substances in representative chrome mist suppressants on the Chinese market.

Fluorinated chrome mist suppressants (CMSs) have been widely used in the electroplating industry globally, including China. In compliance with the Stockholm Convention on Persistent Organic Pollutants, China has phased out perfluorooctane sulfonate (PFOS) as CMS, except for closed-loop systems, before March 2019. Since then, several alternatives have been introduced to replace PFOS, but many of them still belong to the per- and polyfluoroalkyl substances (PFASs) family. In this study, for the first time, we collected and analyzed CMS samples from the Chinese market in 2013, 2015, and 2021 to determine their PFAS composition. For products with relatively few PFAS targets, we performed a total fluorine (TF) screening test and suspect and non-target analysis. Our findings suggest that 6:2 fluorotelomer sulfonate (6:2 FTS) has become the primary alternative on the Chinese market. Surprisingly, we identified 8:2 chlorinated polyfluorinated ether sulfonate (8:2 Cl-PFAES) as the primary ingredient in a CMS product (F-115B), which is the longer chain modification of the classical CMS product (F-53B). Furthermore, we identified three novel PFASs as PFOS alternatives, including hydrogen-substituted perfluoroalkyl sulfonates (H-PFSAs) and perfluorinated ether sulfonates (O-PFSAs). We also screened and identified six hydrocarbon surfactants in PFAS-free products as the primary ingredients. Despite this, some PFOS-based CMSs remain on the Chinese market. To prevent the opportunistic use of PFOS for illegal purposes, it is essential to enforce regulations strictly and ensure that such CMSs are used only in closed-loop chrome plating systems.

Does Musicality Assist Foreign Language Learning? Perception and Production of Thai Vowels, Consonants and Lexical Tones by Musicians and Non-Musicians.

The music and spoken language domains share acoustic properties such as fundamental frequency (f0, perceived as pitch), duration, resonance frequencies, and intensity. In speech, the acoustic properties form an essential part in differentiating between consonants, vowels, and lexical tones. This study investigated whether there is any advantage of musicality in the perception and production of Thai speech sounds. Two groups of English-speaking adults-one comprising formally trained musicians and the other non-musicians-were tested for their perception and production of Thai consonants, vowels, and tones. For both groups, the perception and production accuracy scores were higher for vowels than consonants and tones, and in production, there was also better accuracy for tones than consonants. Between the groups, musicians (defined as having more than five years of formal musical training) outperformed non-musicians (defined as having less than two years of formal musical training) in both the perception and production of all three sound types. Additional experiential factors that positively influenced the accuracy rates were the current hours of practice per week and those with some indication of an augmentation due to musical aptitude, but only in perception. These results suggest that music training, defined as formal training for more than five years, and musical training, expressed in hours of weekly practice, facilitate the perception and production of non-native speech sounds.

Understanding the neural mechanisms for infants' perception of native and non-native speech.

Though perceptual narrowing has been widely recognized as a process guiding cognitive development and category learning in infancy and early childhood, its neural mechanisms and traits at a cortical level remain unclear. Using an electroencephalography (EEG) abstract mismatch negativity (MMN) paradigm, Australian infants' neural sensitivity to (native) English and (non-native) Nuu-Chah-Nulth speech contrasts was examined in a cross-sectional design at the onset (5-6 months) and offset (11-12 months) of perceptual narrowing. Immature mismatch responses (MMR) were observed among younger infants for both contrasts, while older infants showed MMR response to the non-native contrast, and both MMR and MMN to the native contrast. Sensitivity to the Nuu-Chah-Nulth contrast at perceptual narrowing offset was retained yet stayed immature. Findings conform to perceptual assimilation theories, reflecting plasticity in early speech perception and development. Compared to behavioural paradigms, neural examination effectively reveals experience-induced processing differences to subtle contrasts at the offset of perceptual narrowing.

The Relationship between Mindfulness and Readiness to Change in Alcohol Drinkers.

Mindfulness is a multi-faceted construct that involves paying attention to thoughts and emotions without automatically reacting and being critical of them. Recent research has suggested that mindfulness might play an important role in reducing problematic alcohol use. Further, Readiness to Change (RTC) is related to motivation to change drinking behaviours. The RTC scale identifies motivation to change drinking behaviours including Precontemplation, Contemplation, and Action stages. The current study investigated, for the first time, the relationship between mindfulness (and its facets) and RTC in relation to drinking behaviours. Undergraduate students from Western Sydney University (N = 279) were screened for drinking levels using the Alcohol Use Disorder Identification Test (AUDIT) and then completed the Readiness to Change Questionnaire (RCT) and the Five Facets Mindfulness Questionnaire (FFMQ), which includes the following facets: Acting with Awareness, Non-Judging of Inner Experience, Non-Reactivity to Inner Experience, Describing, and Observing. Results show that overall, mindfulness and its facets negatively correlated with RTC. Multiple regression analysis further showed that Awareness and Non-Judgement facets negatively predicted RTC. These findings provide insight into how the facets of mindfulness interact with the drinking motives of individuals and their intentions to change drinking behaviours. Based on these findings, we recommend the incorporation of mindfulness techniques in interventions targeting problematic drinking.

English and Mandarin native speakers' cue-weighting of lexical stress: Results from MMN and LDN.

Past research on how listeners weight stress cues such as pitch, duration and intensity has reported two inconsistent patternss: listeners' weighting conforms to 1) their native language experience (e.g., language rhythmicity, lexical tone), and 2) a general "iambic-trochaic law" (ITL), favouring innate sound groupings in cue perception. This study aims to tease apart the above effects by investigating the weighting of pitch, duration and intensity cues in stress-timed (Australian English) and non-stress-timed and tonal (Taiwan Mandarin) language speaking adults using a mismatch negativity (MMN) multi-feature paradigm. Results show effects that can be explained by language-specific rhythmic influence, but only partially by the ITL. Moreover, these findings revealed cross-linguistic differences indexed by both MMN and late discriminative negativity (LDN) responses at cue and syllable position levels, and thus call for more sophisticated perspectives for existing cue-weighting models.

Suspect screening and nontargeted analysis of per- and polyfluoroalkyl substances in representative fluorocarbon surfactants, aqueous film-forming foams, and impacted water in China.

Massive usage of aqueous film-forming foams (AFFF) containing fluorocarbon surfactants (FS) is one of the major sources of per- and polyfluoroalkyl substances (PFAS) contamination, which poses negative environmental and health effects. However, there is a critical knowledge gap regarding PFAS chemical compositions in high consumption FS products which were used in AFFFs on the Chinese market and in water impacted by such products. This study firstly applied a comprehensive suspect screening and nontargeted analysis (NTA) workflow to investigate the main ionic and neutral PFAS in FS products from the largest Chinese vendor and compared with two international brands to unveil the PFAS used in AFFF. Overall, 24 classes of PFAS, including 69 compounds, were tentatively identified in FS products, and high concentrations of neutral PFAS were found in polymer-based products, indicating potential environmental risk. In addition, we applied a simplified data mining process to capture 36 PFAS from the impacted water, and the relationship among FS, AFFF concentrates and impacted water was explored. This study parsed the PFAS characteristics in AFFF-related industrial products and impacted water in China, which is instrumental for managing and controlling prioritized PFAS in this field.

How Tone, Intonation and Emotion Shape the Development of Infants' Fundamental Frequency Perception.

Fundamental frequency (ƒ 0), perceived as pitch, is the first and arguably most salient auditory component humans are exposed to since the beginning of life. It carries multiple linguistic (e.g., word meaning) and paralinguistic (e.g., speakers' emotion) functions in speech and communication. The mappings between these functions and ƒ 0 features vary within a language and differ cross-linguistically. For instance, a rising pitch can be perceived as a question in English but a lexical tone in Mandarin. Such variations mean that infants must learn the specific mappings based on their respective linguistic and social environments. To date, canonical theoretical frameworks and most empirical studies do not view or consider the multi-functionality of ƒ 0, but typically focus on individual functions. More importantly, despite the eventual mastery of ƒ 0 in communication, it is unclear how infants learn to decompose and recognize these overlapping functions carried by ƒ 0. In this paper, we review the symbioses and synergies of the lexical, intonational, and emotional functions that can be carried by ƒ 0 and are being acquired throughout infancy. On the basis of our review, we put forward the Learnability Hypothesis that infants decompose and acquire multiple ƒ 0 functions through native/environmental experiences. Under this hypothesis, we propose representative cases such as the synergy scenario, where infants use visual cues to disambiguate and decompose the different ƒ 0 functions. Further, viable ways to test the scenarios derived from this hypothesis are suggested across auditory and visual modalities. Discovering how infants learn to master the diverse functions carried by ƒ 0 can increase our understanding of linguistic systems, auditory processing and communication functions.

Learning to Perceive Non-Native Tones via Distributional Training: Effects of Task and Acoustic Cue Weighting.

As many distributional learning (DL) studies have shown, adult listeners can achieve discrimination of a difficult non-native contrast after a short repetitive exposure to tokens falling at the extremes of that contrast. Such studies have shown using behavioural methods that a short distributional training can induce perceptual learning of vowel and consonant contrasts. However, much less is known about the neurological correlates of DL, and few studies have examined non-native lexical tone contrasts. Here, Australian-English speakers underwent DL training on a Mandarin tone contrast using behavioural (discrimination, identification) and neural (oddball-EEG) tasks, with listeners hearing either a bimodal or a unimodal distribution. Behavioural results show that listeners learned to discriminate tones after both unimodal and bimodal training; while EEG responses revealed more learning for listeners exposed to the bimodal distribution. Thus, perceptual learning through exposure to brief sound distributions (a) extends to non-native tonal contrasts, and (b) is sensitive to task, phonetic distance, and acoustic cue-weighting. Our findings have implications for models of how auditory and phonetic constraints influence speech learning.

The tone atlas of perceptual discriminability and perceptual distance: Four tone languages and five language groups.

Some prior investigations suggest that tone perception is flexible, reasonably independent of native phonology, whereas others suggest it is constrained by native phonology. We address this issue in a systematic and comprehensive investigation of adult tone perception. Sampling from diverse tone and non-tone speaking communities, we tested discrimination of the three major tone systems (Cantonese, Thai, Mandarin) that dominate the tone perception literature, in relation to native language and language experience as well as stimulus variation (tone properties, presentation order, pitch cues) using linear mixed effect modelling and multidimensional scaling. There was an overall discrimination advantage for tone language speakers and for native tones. However, language- and tone-specific effects, and presentation order effects also emerged. Thus, over and above native phonology, stimulus variation exerts a powerful influence on tone discrimination. This study provides a tone atlas, a reference guide to inform empirical studies of tone sensitivity, both retrospectively and prospectively.

Degradation of OBS (Sodium p-Perfluorous Nonenoxybenzenesulfonate) as a Novel Per- and Polyfluoroalkyl Substance by UV/Persulfate and UV/Sulfite: Fluorinated Intermediates and Treatability in Fluoroprotein Foam.

Sodium p-perfluorous nonenoxybenzenesulfonate (OBS) is a novel fluorosurfactant used as the alternative to perfluorooctanesulfonic acid (PFOS) in several applications such as fire-fighting foams and chemical enhanced oil recovery ("EOR") in China, with the annual production capacity of about 3,500 t. Here, for the first time, we investigated the degradability of OBS under the conditions of UV/persulfate (UV/PS) and UV/sulfite (UV/SF) as typical redox processes. A higher reaction rate (1.05 min-1) and total organic carbon (TOC) reduction (46.9%) but a low defluorination rate (27.6%) along with the formation of a series of fluorinated intermediates were found in UV/PS, while a high defluorination rate (87.7%) was realized in UV/SF. In particular, a nontargeted workflow using high performance liquid chromatography-quadrupole time-of-flight mass spectrometry (HPLC/Q-TOF-MS) was established to detect fluorinated intermediates. Combined with the theoretical calculation, the distinctive degradation pathways in both oxidation and reduction processes were proposed. The degradation mechanism of OBS in UV/SF was proposed to be H/F exchange and subsequent HF elimination. Furthermore, the diluted OBS-based fluoroprotein (FP) foam was used to investigate the degradation of OBS, which confirms the treatability using the redox approach. This work provides insights into the degradability of OBS, fluorinated intermediate search, and proper treatment of related contamination.

Infants are sensitive to cultural differences in emotions at 11 months.

A myriad of emotion perception studies has shown infants' ability to discriminate different emotional categories, yet there has been little investigation of infants' perception of cultural differences in emotions. Hence little is known about the extent to which culture-specific emotion information is recognised in the beginning of life. Caucasian Australian infants of 10-12 months participated in a visual-paired comparison task where their preferential looking patterns to three types of infant-directed emotions (anger, happiness, surprise) from two different cultures (Australian, Japanese) were examined. Differences in racial appearances were controlled. Infants exhibited preferential looking to Japanese over Caucasian Australian mothers' angry and surprised expressions, whereas no difference was observed in trials involving East-Asian Australian mothers. In addition, infants preferred Caucasian Australian mothers' happy expressions. These findings suggest that 11-month-olds are sensitive to cultural differences in spontaneous infant-directed emotional expressions when they are combined with a difference in racial appearance.

Self-Internal-Reference Probe System for Control-Free Quantification of Mutation Abundance.

Gene mutations are important biomarkers for the diagnosis, classification, monitoring, and prognosis evaluation of cancers and genetic diseases. Both personalized cancer treatment and noninvasive prenatal testing require methods to accurately determine the abundance of mutation. At present, the widely adopted and convenient methods for measuring mutation abundance are mainly based on relative quantification, which requires negative samples and strict control of the analyte amounts. The development of DNA-probe-based methods that can determine the mutation abundance without negative samples nor control of analyte amount is highly preferred. The key to solving this bottleneck lies in whether the probe's response to mutation abundance can be completely independent of the number of targeted DNA strands. Herein, we propose the design of a self-internal-reference probe system. We established a theoretical model of this system and used the model to guide the design of probes. In this model, we provided quantitative corrections to the test results from the internal reference, thereby eliminating the influence of substrate amount. Therefore, the purification and quantification processes toward polymerase chain reaction (PCR) amplicons can be omitted. We applied this system to analyze unquantified PCR products aimed at cancer mutation detection and noninvasive prenatal testing.

Multifunctional Clip Strand for the Regulation of DNA Strand Displacement and Construction of Complex DNA Nanodevices.

Strand displacement reactions are important bricks for the construction of various DNA nanodevices, among which the toehold-mediated strand displacement reaction is the most prevalently adopted. However, only a limited number of tools could be used to finely regulate the toehold reaction, thus restricting DNA nanodevices from being more multifunctional and powerful. Herein, we developed a regulation tool, Clip, and achieved multiple regulatory functions, including subtle adjustment of the reaction rates, allosteric strand displacement, selective activation, and resetting of the reaction. Taking advantages of the multiple functions, we constructed Clip-toehold-based DNA walking machines. They showed behaviors of controllable walking, concatenation, and programmable pathways. Furthermore, we built Clip-toehold-based AND and OR logic gates and integrated those logic gates to construct multilayer circuits, which could be reset and reused to process different input signals. We believe that the proposed Clip tool has expanded the functionality of DNA strand displacement-based nanodevices to a much more complex and diverse level and anticipate that the tool will be widely adopted in DNA nanotechnology.

Identification of biomarkers, pathways and potential therapeutic target for docetaxel resistant prostate cancer.

Docetaxel has been proved to provide survival benefit for advanced prostate cancer (PCa) patients. Resistance to docetaxel further reduces the survival of these patients. Herein, we performed a comprehensive bioinformatic analysis to identify differentially expressed genes (DEGs) between docetaxel sensitive and resistant PCa (DRPC) cell based on Gene Expression Omnibus (GEO) database. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were applied for functional and pathway analysis of DEGs. The STRING database, cytoscape software and plug-in 'cytoHubba' were used to construct protein-protein interaction (PPI) networks and identify hub genes. Survival analysis were performed via GEPIA database. Finally, we conducted immune infiltration analysis by TIMER. A total of 460 DEGs were identified. GO functional analysis showed that these DEGs are mainly enriched in chemotaxis, negative regulation of intracellular signal transduction, and regulation of cell adhesion, positive regulation of inflammatory response, regulation of response to cytokine stimulus. According to the results of KEGG pathway analysis, these DEGs are mainly involved in signaling by Rho GTPases, Miro GTPases and RHOBTB3; interferon Signaling; arginine biosynthesis; PI3K-Akt signaling pathway; cytokine-cytokine receptor interaction; MAPK signaling pathway. Finally, CCNB1 and EZH2 were identified as prognostic hub genes and the expression of these two genes were associated with immune infiltration. The present study may helps to improve the understanding of the molecular mechanisms of DRPC and facilitate the selection of therapeutic and prognostic biomarkers for DRPC.

Antibiotic resistance genes and mobile genetic elements in a rural river in Southeast China: Occurrence, seasonal variation and association with the antibiotics.

Human activities in rural areas, such as livestock farming, aquaculture, and rural domestic sewage discharge, may result in antibiotic resistance genes (ARGs) pollution in rural rivers. A systematic monitoring in different seasons was conducted in a typical agriculture-polluted river with Real-Time Quantitative PCR. A total of 11 ARGs and 2 related mobile genetic elements (MGEs) were detected at all sites with relative abundances of 6.9 × 10-10-0.2 copies/16S rRNA copies. Among them, sul1, sul2 and int1 were the dominant target genes in water samples. tetW, ermB, and floR were more abundant in November (the dry season), while other ARGs, MGEs and 16s rRNA were at a higher absolute abundance in warm seasons. There was less spatial variation of ARGs in the dry season than in the other two seasons. Furthermore, the relative abundance of ARGs was higher at sampling sites adjoining pollution sources. In addition, cluster analysis implied that ARGs in upstream sediments may be released into surface water and migrate downstream in the direction of river flow. There was no significant correlation between ARGs and their corresponding antibiotics. However, the total concentration of tetracycline was significantly correlated with the non-paired ARGs, including sul3, floR, and ermB. At the same time, heavy metals (Zn, Pb, Cd, Cr6+, As) and other environmental parameters (permanganate index, pH, DO) may apply selective pressure on the spread of ARGs, according to redundancy and Pearson's correlation analysis.

A multi-lab study of bilingual infants: Exploring the preference for infant-directed speech.

From the earliest months of life, infants prefer listening to and learn better from infant-directed speech (IDS) than adult-directed speech (ADS). Yet, IDS differs within communities, across languages, and across cultures, both in form and in prevalence. This large-scale, multi-site study used the diversity of bilingual infant experiences to explore the impact of different types of linguistic experience on infants' IDS preference. As part of the multi-lab ManyBabies 1 project, we compared lab-matched samples of 333 bilingual and 385 monolingual infants' preference for North-American English IDS (cf. ManyBabies Consortium, 2020: ManyBabies 1), tested in 17 labs in 7 countries. Those infants were tested in two age groups: 6-9 months (the younger sample) and 12-15 months (the older sample). We found that bilingual and monolingual infants both preferred IDS to ADS, and did not differ in terms of the overall magnitude of this preference. However, amongst bilingual infants who were acquiring North-American English (NAE) as a native language, greater exposure to NAE was associated with a stronger IDS preference, extending the previous finding from ManyBabies 1 that monolinguals learning NAE as a native language showed a stronger preference than infants unexposed to NAE. Together, our findings indicate that IDS preference likely makes a similar contribution to monolingual and bilingual development, and that infants are exquisitely sensitive to the nature and frequency of different types of language input in their early environments.