1.
Chem Commun (Camb)
; 60(32): 4306-4309, 2024 Apr 16.
Artículo
en Inglés
| MEDLINE
| ID: mdl-38533558
RESUMEN
A radical 1,4-aryl migration enabling a cross-electrophile coupling reaction toward remote transalkylation of N-benzyl alanine has been developed. In this strategy, with the occurrence of a radical-mediated Turce-Smiles rearrangement, key α-aminoalkyl radicals are generated. The as-formed α-aminoalkyl radical serves as a robust coupling partner for cross-electrophilic coupling with vinyl triflates, affording a series of olefin-tethered amino acid motifs.