Psychological impact of first-trimester prevention for preeclampsia on anxiety.

OBJECTIVE: This study aims to examine whether a first-trimester strategy of secondary prevention for preeclampsia increases anxiety in pregnant women. METHODS: The anxiety levels of a cohort of women screened for preeclampsia at first trimester were measured by the Spielberg State-Trait Anxiety Inventory (STAI-S) and compared between women screened as low and high risk. In a subgroup of women, the anxiety levels were additionally measured at second and third trimester. A General Linear Model (GLM) for repeated measurements was performed to adjust for potential confounders (age, nulliparity and socio-economic level). RESULTS: A total of 255 women (135 low-risk and 120 high-risk) were evaluated. No differences were found in the mean STAI-S scores between low-risk and high-risk women: 35 (SD 9.9) and 34.6 (SD 10.1); p = 0.77. The proportion of women with high anxiety was not significantly different between groups (28/134 [20.7%] vs 24/120 [20%]; p = 0.88). No differences were found in the subgroups (51 low-risk and 50 high-risk) in which the anxiety levels were also measured at second and third trimester: 35.8 (SD 8.8) vs 35.2 (SD 9.7), p = 0.74, and 37.2 (SD 9.4) vs 35.3 (SD 8.6), p = 0.3. These differences remained non-significant after adjustment for potential confounders. CONCLUSION: A strategy of first-trimester screening for preeclampsia does not increase maternal anxiety.

Prevalence and correlates of mild cognitive impairment in adults aged over 50 years with subjective cognitive complaints in primary care centers.

AIM: To examine the prevalence and correlates of mild cognitive impairment in adults aged over 50 years attending primary care centers with complaints of cognitive failure. METHODS: A sample of 689 individuals aged ≥ 50 years with no previous diagnosis of dementia was assessed by use of the Mini-Mental State Examination, the Cambridge Cognitive Examination-Revised and the California Verbal Learning Test--to evaluate the mild cognitive impairment as dependent variables--and administration of a questionnaire on cognitive complaints and other instruments--to measure correlates. RESULTS: The prevalence of mild cognitive impairment was 31.40%, and positive associations were found for age, occupation, subjective memory complaints, reading habits and level of vocabulary. In the logistic regression, modeled mild cognitive impairment was associated with age (70 years or older), subjective cognitive complaints and level of vocabulary. CONCLUSION: Almost one-third of the adults aged ≥ 50 years attending primary care centers with subjective cognitive complaints were affected by mild cognitive impairment. Early evaluation of cognitive functioning is essential to establish adequate preventive and intervention strategies.

Prevalence and correlates of cognitive impairment in adults with subjective memory complaints in primary care centres.

AIMS: To examine the prevalence and correlates of cognitive impairment (CI) in adults over 50 years old attending primary care centres with complaints of memory failure. METHODS: A sample of 580 individuals aged 50+ years with no previous diagnosis of dementia was assessed by use of the Mini Mental State Examination, the Cambridge Cognitive Assessment-Revised and the California Verbal Learning Test - to evaluate CI-dependent variables - and administration of a questionnaire on memory complaints and other instruments - to measure correlates. RESULTS: The prevalence of CI was 46.20% and positive associations were found for age, gender, level of education, subjective memory complaints, instrumental activities of daily living, reading habits and frequency of leisure activities. In the logistic regression, modelled CI was associated with older age, gender (49.12% women, 39.66% men), instrumental activities of daily living, and reading habits. CONCLUSION: Almost half of the adults aged 50+ years attending primary care centres with subjective memory complaints were affected by CI. Early evaluation of cognitive functioning is essential to establish adequate preventive and intervention strategies.