RESUMEN
BACKGROUND: Some lesions not included in the Banff classification, such as inflammation in the scarred areas and total inflammation, have been described to have prognostic value in the evaluation of graft biopsies. Our aim was to reassess kidney graft biopsies and study the impact of histopathologic lesions, both those graded in the Banff classification and those related to inflammation, on the graft function and evolution. METHODS: We selected 20 biopsies exhibiting chronic pathology without a specific phenotype, and we reevaluated them with the use of a modified Banff score. RESULTS: We found statistically significant association between the presence of total inflammation (P = .048; P = .038), the presence of inflammation in scared area (P = .037; P = .018), and creatinine at the time of renal biopsy and 1 year after the renal biopsy, respectively. CONCLUSIONS: Our results suggest that the presence of both inflammation in the scarred areas and total inflammation are related to renal function at the time of the biopsy and to renal function 1 year after the biopsy.
Asunto(s)
Trasplante de Riñón , Riñón/patología , Trasplantes/patología , Biopsia , Enfermedad Crónica , Cicatriz/patología , Creatinina/metabolismo , Femenino , Rechazo de Injerto/patología , Humanos , Masculino , Persona de Mediana Edad , Nefrectomía/métodos , Nefritis/patología , Nefritis/fisiopatología , Puntuaciones en la Disfunción de Órganos , Pronóstico , Trasplantes/fisiopatologíaAsunto(s)
Colitis/etiología , Infecciones por Citomegalovirus/complicaciones , Infecciones Oportunistas/complicaciones , Antígenos Virales/análisis , Colonoscopía , Citomegalovirus/inmunología , Infecciones por Citomegalovirus/diagnóstico , Diagnóstico Diferencial , Femenino , Humanos , Huésped Inmunocomprometido , Inmunosupresores/administración & dosificación , Inmunosupresores/efectos adversos , Inmunosupresores/uso terapéutico , Lupus Eritematoso Sistémico/complicaciones , Lupus Eritematoso Sistémico/tratamiento farmacológico , Nefritis Lúpica/complicaciones , Nefritis Lúpica/tratamiento farmacológico , Metilprednisolona/administración & dosificación , Metilprednisolona/efectos adversos , Metilprednisolona/uso terapéutico , Ácido Micofenólico/administración & dosificación , Ácido Micofenólico/efectos adversos , Ácido Micofenólico/análogos & derivados , Ácido Micofenólico/uso terapéutico , Nocardiosis/complicaciones , Infecciones Oportunistas/diagnóstico , Neumatosis Cistoide Intestinal/etiología , Infecciones del Sistema Respiratorio/complicacionesRESUMEN
Presentation of one case of fibrous pseudotumor of epididymis in a 33 year-old patient. Final diagnosis was achieved after surgical exeresis and its pathoanatomical examination. Etiopathogeny, clinic presentation and therapeutical approach are reviewed. Considering, in general, the clinical inespecificity of intrascrotal processes, we believe it is important to know this entity in order to be in a position to address differential diagnosis with truly neoplastic processes.