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J Palliat Med ; 22(2): 231-233, 2019 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-30376403

RESUMEN

BACKGROUND: Olanzapine is commonly utilized in palliative care for the treatment of nausea, and a known side effect of olanzapine is increased appetite. Olanzapine is also known to cause re-emergence of eating disorders (EDs) in patients utilizing olanzapine for its antipsychotic effects. It is unclear to what extent this may also occur in patients with serious/life-limiting illness. METHODS AND RESULTS: We present a case of a 70-year-old female with recurrent ovarian cancer and a history of bulimia nervosa (BN) that developed resurgence of her BN after initiation of olanzapine for cancer-associated nausea. Her BN resolved with reducing the dose of olanzapine. CONCLUSION: It is important to recognize that recurrence of EDs can occur when using olanzapine in the palliative care setting.


Asunto(s)
Antineoplásicos/efectos adversos , Bulimia Nerviosa/inducido químicamente , Bulimia Nerviosa/tratamiento farmacológico , Náusea/inducido químicamente , Náusea/tratamiento farmacológico , Olanzapina/uso terapéutico , Neoplasias Ováricas/tratamiento farmacológico , Anciano , Antineoplásicos/uso terapéutico , Antipsicóticos/uso terapéutico , Apetito/efectos de los fármacos , Femenino , Humanos , Cuidados Paliativos/métodos , Resultado del Tratamiento
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