1.
Chem Commun (Camb)
; 60(29): 3958-3961, 2024 Apr 04.
Artículo
en Inglés
| MEDLINE
| ID: mdl-38501223
RESUMEN
A novel and interesting controllable spirocyclization of unsaturated barbiturates with enamino esters for the assembly of cyclopentenyl and pyrrolinyl spirobarbiturates has been developed under ball-milling conditions. The present protocol features high chemoselectivity and efficiency, excellent functional group tolerance and mild reaction conditions.