[Effect of acute intestinal obstruction on erythrocyte membrane function]. / Vliianie ostroi neprokhodimosti kishechnika na sostoianie membran éritrotsitov.

The amino acid composition of red blood cell membrane proteins had been studied in different stages of acute intestinal obstruction. Hydrophobic amino acids were revealed to increase and glutamate was found to decrease during the early period of acute intestinal obstruction. Later neutral amino acids and some of the main amino acids were stated to decrease. Shifts in the ratio of protein fractions seen in red blood cell membrane of rats with acute intestinal obstruction could be explained by changes followed in the amino acid composition. The data accumulated had demonstrated that such a significant modification of protein component of the red blood cell membrane could be one of the reasons of the erythrocyte membrane penetrability violation and could play the pathogenetic role in the occurrence of irreversibility changes in cases of the intestinal obstruction. All that was mentioned above had shown the necessity to use membrane protectors and antienzyme drugs in the postoperative period.

[A common concept of the pathogenesis of intestinal obstruction]. / O edinoi kontseptsii patogeneza neprokhodimosti kishechnika.

On the basis of personal investigations and literature data the authors make a conclusion of the common nature of pathogenesis of acute ileus and various kinds of shock reactions. This common nature is determined by the character of trigger mechanisms of pathological reactions and formation of defense reactions of the patient.