1.
Chem Commun (Camb)
; 55(61): 8919-8922, 2019 Aug 07.
Artículo
en Inglés
| MEDLINE
| ID: mdl-31270526
RESUMEN
Cancer development is often associated with lipid metabolic reprogramming, including aberrant lipid accumulation. We create novel paradigms endowed with dual functions of anticancer activity and inhibition of lipid accumulation by conjugating the natural product quercetin and synthetic alkylphospholipid drugs, and harnessing the biomedical effects of both. These conjugates offer fresh perspectives in the search for anticancer candidates.