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Trans R Soc Trop Med Hyg ; 117(3): 197-204, 2023 03 01.
Artículo en Inglés | MEDLINE | ID: mdl-36353973

RESUMEN

BACKGROUND: Hepatitis A virus (HAV) and hepatitis E virus (HEV) have enteric modes of transmission and are common causes of acute hepatitis in low- and middle-income countries. HEV is also characterised as a zoonotic infection and is prevalent in high-income countries. Data on HAV and HEV prevalence in Suriname, a middle-income country in South America, are scarce. METHODS: Serum samples of 944 and 949 randomly selected patients attending the Emergency Department at the Academic Hospital of Paramaribo, the capital of Suriname, were analysed for anti-HAV antibodies (anti-HAV) and anti-HEV antibodies (anti-HEV), respectively. Determinants of anti-HAV and anti-HEV positive serology were evaluated using multivariable logistic regression. RESULTS: Anti-HAV prevalence was 58.3% (95% CI 55.4 to 61.4%) and higher prevalence was independently associated with belonging to the Tribal or Indigenous population and older age. Anti-HEV prevalence was 3.7% (95% CI 2.6 to 5.0%) and higher prevalence was associated with Tribal and Creole ethnicity and older age. CONCLUSIONS: In Suriname, exposure to HAV is consistent with a very low endemic country and exposure to HEV was rare. Both viruses were more prevalent in specific ethnic groups. As anti-HAVantibodies were less frequently found in younger individuals, they could be susceptible to potential HAV outbreaks and might require HAV vaccination.


Asunto(s)
Virus de la Hepatitis A , Hepatitis A , Virus de la Hepatitis E , Hepatitis E , Humanos , Hepatitis A/epidemiología , Anticuerpos de Hepatitis A , Hepatitis E/epidemiología , Estudios Seroepidemiológicos , Suriname , Anticuerpos Antihepatitis , Prevalencia , Servicio de Urgencia en Hospital
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