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J Thorac Cardiovasc Surg ; 159(5): 1957-1965.e1, 2020 05.
Artículo en Inglés | MEDLINE | ID: mdl-31982128

RESUMEN

OBJECTIVES: Acute coronary artery obstruction is a rare complication of congenital heart disease surgery but imposes a high burden of morbidity and mortality. Previous case series have described episodes in specific congenital heart lesions or surgical repairs but have not examined the complication in all-comers to congenital heart surgery. We hypothesize that shorter time from a clinically recognized postoperative sentinel event suggestive of coronary ischemia to diagnosis of coronary obstruction is associated with improved clinical outcomes. METHODS: This was a single-center, retrospective review of patients diagnosed with acute coronary artery obstruction by angiography following surgical repair of congenital heart disease between January 2000 and June 2016. RESULTS: In total, 34 patients were identified. The most common procedures associated with coronary artery obstruction were the Norwood procedure, arterial switch operation, and aortic valve repair/replacement. In total, 79% required mechanical circulatory support, 41% died, and 27% were listed for heart transplant. Patients who died or were listed for heart transplant had longer median sentinel-event-to-cardiac-catheterization time (28 [6-168] hours vs 10 [3-56] hours, P = .001), and longer median sentinel-event-to-intervention time (32 [11-350] hours vs 13 [5-59] hours, P = .003). Patients with hypoplastic left heart syndrome were at greater risk of death or transplant listing (odds ratio, 9.23, P = .03). CONCLUSIONS: Time from clinically relevant postoperative sentinel event to diagnosis of coronary artery obstruction by angiography was associated with transplant-listing-free survival. Clinicians should maintain a high index of suspicion for coronary obstruction and consider early catheterization and coronary angiography for patients in whom post-operative coronary compromise is suspected.


Asunto(s)
Procedimientos Quirúrgicos Cardíacos/efectos adversos , Oclusión Coronaria , Cardiopatías Congénitas/cirugía , Complicaciones Posoperatorias , Adolescente , Adulto , Niño , Preescolar , Oclusión Coronaria/epidemiología , Oclusión Coronaria/mortalidad , Oclusión Coronaria/cirugía , Vasos Coronarios/fisiopatología , Vasos Coronarios/cirugía , Femenino , Humanos , Lactante , Recién Nacido , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias/epidemiología , Complicaciones Posoperatorias/mortalidad , Complicaciones Posoperatorias/cirugía , Estudios Retrospectivos , Adulto Joven
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