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Tidsskr Nor Laegeforen ; 139(8)2019 May 07.
Artículo en Noruego, Inglés | MEDLINE | ID: mdl-31062563

RESUMEN

BACKGROUND: For more than 20 years, intramuscular injections of botulinum toxin A have been an established treatment for spasticity in children with cerebral palsy. We investigated the proportion of children with cerebral palsy who receive such treatment in Norway and the guidelines that apply to the treatment. MATERIAL AND METHOD: Data from the five-year registration in the Cerebral Palsy Registry of Norway were used to investigate the proportion of children with cerebral palsy born in the period 1999-2010 treated with botulinum toxin A, and whether there were any variations in the proportion of children treated between the habilitation centres. We conducted an online survey to identify the treatment guidelines that were applied in all of the 21 habilitation centres. RESULTS: A total of 1 414 children (average age 6.3 years) were included, of whom 775 (55 %) had been treated with botulinum toxin A. The proportion of children who received treatment varied considerably between the habilitation centres (38-80 %; p < 0.001). The maximum dose of botulinum toxin A per treatment per patient was 200-600 units of Botox. Five centres reported to have written guidelines for the treatment indication. INTERPRETATION: The proportion of children with cerebral palsy who are treated with botulinum toxin A varies considerably between Norwegian habilitation centres.


Asunto(s)
Toxinas Botulínicas Tipo A , Parálisis Cerebral/tratamiento farmacológico , Fármacos Neuromusculares , Baclofeno/administración & dosificación , Baclofeno/uso terapéutico , Toxinas Botulínicas Tipo A/administración & dosificación , Toxinas Botulínicas Tipo A/uso terapéutico , Parálisis Cerebral/complicaciones , Parálisis Cerebral/epidemiología , Niño , Estudios Transversales , Femenino , Humanos , Masculino , Relajantes Musculares Centrales/administración & dosificación , Relajantes Musculares Centrales/uso terapéutico , Espasticidad Muscular/tratamiento farmacológico , Espasticidad Muscular/etiología , Fármacos Neuromusculares/administración & dosificación , Fármacos Neuromusculares/uso terapéutico , Noruega/epidemiología , Procedimientos Ortopédicos , Guías de Práctica Clínica como Asunto , Sistema de Registros , Centros de Rehabilitación , Encuestas y Cuestionarios
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