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1.
J R Soc Interface ; 15(141)2018 04.
Artículo en Inglés | MEDLINE | ID: mdl-29695604

RESUMEN

This paper describes the use of the electrostatic element of an electrostatic/gecko-like adhesive to repel dust particles, which have been shown to significantly affect adhesion and reliability. The result is a non-destructive, non-contact cleaning method that can be used in conjunction with other cleaning techniques, many of which rely on physical contact between the fibrillar adhesive and substrate. The paper focuses on experimental evaluation of the repulsion of 100 µm glass beads as a function of wave shape, frequency, phase number and electrode direction in relation to the gecko-like features. Results show that a two-phase square wave with the lowest practically feasible frequency can remove 100 µm glass beads from a directional gecko-like adhesive with up to 70% efficiency. Finally, using the optimized electrostatic cleaning properties, results show an approximately 25% recovery in shear stress on a rough glass for three contaminated directional gecko-like adhesives after contact with a dusty table.


Asunto(s)
Adhesivos/química , Lagartos , Electricidad Estática , Adhesividad , Animales , Fenómenos Biomecánicos , Polvo , Fricción , Reproducibilidad de los Resultados
2.
PLoS One ; 11(4): e0152873, 2016.
Artículo en Inglés | MEDLINE | ID: mdl-27074019

RESUMEN

BACKGROUND: An autogenous arteriovenous fistula is the optimal vascular access for hemodialysis. In the case of brachiocephalic fistula, cephalic arch stenosis commonly develops leading to access failure. We have hypothesized that a contribution to fistula failure is low wall shear stress resulting from post-fistula creation hemodynamic changes that occur in the cephalic arch. METHODS: Twenty-two subjects with advanced renal failure had brachiocephalic fistulae placed. The following procedures were performed at mapping (pre-operative) and at fistula maturation (8-32 weeks post-operative): venogram, Doppler to measure venous blood flow velocity, and whole blood viscosity. Geometric and computational modeling was performed to determine wall shear stress and other geometric parameters. The relationship between hemodynamic parameters and clinical findings was examined using univariate analysis and linear regression. RESULTS: The percent low wall shear stress was linearly related to the increase in blood flow velocity (p < 0.01). This relationship was more significant in non-diabetic patients (p < 0.01) than diabetic patients. The change in global measures of arch curvature and asymmetry also evolve with time to maturation (p < 0.05). CONCLUSIONS: The curvature and hemodynamic changes during fistula maturation increase the percentage of low wall shear stress regions within the cephalic arch. Low wall shear stress may contribute to subsequent neointimal hyperplasia and resultant cephalic arch stenosis. If this hypothesis remains tenable with further studies, ways of protecting the arch through control of blood flow velocity may need to be developed.


Asunto(s)
Derivación Arteriovenosa Quirúrgica , Velocidad del Flujo Sanguíneo/fisiología , Tronco Braquiocefálico/fisiopatología , Fallo Renal Crónico/terapia , Adulto , Anciano , Anciano de 80 o más Años , Tronco Braquiocefálico/cirugía , Femenino , Humanos , Fallo Renal Crónico/fisiopatología , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Estrés Mecánico , Adulto Joven
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