Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 54
Filtrar
Más filtros









Base de datos
Intervalo de año de publicación
1.
In Science Journals.
Malo, Courtney; Funk, Michael A; Ash, Caroline; Szuromi, Phil; Grocholski, Brent; Stajic, Jelena; Lopez, Bianca; Ross, Sarah H; Simonti, Corinne N; Jiang, Di; Maroso, Mattia; Kelly, Priscilla N; Lavine, Marc S; Isles, Hannah; Ferrarelli, Leslie K.
Science ; 385(6704): 39-41, 2024 Jul 05.
Artículo en Inglés | MEDLINE | ID: mdl-38963851

RESUMEN

Highlights from the Science family of journals.

2.
In Science Journals.
Smith, Jesse; Funk, Michael A; Stern, Peter; Osborne, Ian S; Smith, Keith T; Maroso, Mattia; Yeston, Jake S; Grocholski, Brent; Foley, John F; Simonti, Corinne N; Jiang, Di; Szuromi, Phil; Isles, Hannah M; Malo, Courtney.
Science ; 385(6707): 402-404, 2024 Jul 26.
Artículo en Inglés | MEDLINE | ID: mdl-39052784

RESUMEN

Highlights from the Science family of journals.

3.
In Science Journals.
Smith, Keith T; Maroso, Mattia; Osborne, Ian S; Hurtley, Stella M; Szuromi, Phil; Jiang, Di; Malo, Courtney; Ross, Sarah H; Kelly, Priscilla N; Lavine, Marc S; Stern, Peter; Ray, L Bryan; Suleymanov, Yury; Fogg, Christiana; Foley, John F.
Science ; 384(6700): 1078-1080, 2024 Jun 07.
Artículo en Inglés | MEDLINE | ID: mdl-38843347

RESUMEN

Highlights from the Science family of journals.

4.
In Science Journals.
Vignieri, Sacha; Lavine, Marc S; Szuromi, Phil; Lopez, Bianca; Jiang, Di; Wong, Wei; Matsiko, Amos; Nusinovich, Yevgeniya; Maroso, Mattia; Smith, Keith T; Olingy, Claire; Malo, Courtney.
Science ; 384(6698): 871-873, 2024 May 24.
Artículo en Inglés | MEDLINE | ID: mdl-38781360

RESUMEN

Highlights from the Science family of journals.

5.
In Science Journals.
Smith, Jesse; Lavine, Marc S; Szuromi, Phil; Vignieri, Sacha; Grocholski, Brent; Olingy, Claire; Simonti, Corinne; Yashinski, Melisa; Maroso, Mattia; Nusinovich, Yevgeniya; Uzogara, Ekeoma; Osborne, Ian S; Malo, Courtney; Wong, Wei.
Science ; 384(6699): 972-974, 2024 May 31.
Artículo en Inglés | MEDLINE | ID: mdl-38815036

RESUMEN

Highlights from the Science family of journals.

6.
In Science Journals.
Lopez, Bianca; Stajic, Jelena; Jiang, Di; Szuromi, Phil; Aldenderfer, Mark; Grocholski, Brent; Seale, Madeleine; Malo, Courtney; Ross, Sarah H; Ash, Caroline; Hurtley, Stella M; Nusinovich, Yevgeniya; Funk, Michael A; Yeston, Jake S; VanHook, Annalisa M; Isles, Hannah M.
Science ; 384(6691): 43-45, 2024 Apr 05.
Artículo en Inglés | MEDLINE | ID: mdl-38574135

RESUMEN

Highlights from the Science family of journals.

7.
In Science Journals.
Walia, Ankit; Lavine, Marc S; Osborne, Ian S; Smith, H Jesse; Suleymanov, Yury; Stern, Peter; Yang, Ming; Malo, Courtney; Alderton, Gemma; Funk, Michael A; Jiang, Di; Ash, Caroline; Grocholski, Brent; Ray, L Bryan; Olingy, Claire; Ferrarelli, Leslie K.
Science ; 383(6690): 1428-1429, 2024 Mar 29.
Artículo en Inglés | MEDLINE | ID: mdl-38547286

RESUMEN

Highlights from the Science family of journals.

8.
In Science Journals.
Matsiko, Amos; Szuromi, Phil; Lopez, Bianca; Jiang, Di; Grocholski, Brent; Yeston, Jake S; Malo, Courtney; Ash, Caroline; Smith, H Jesse; Lavine, Marc S; Maroso, Mattia; Fogg, Christiana N; Wong, Wei.
Science ; 383(6688): 1190-1191, 2024 Mar 15.
Artículo en Inglés | MEDLINE | ID: mdl-38484047

RESUMEN

Highlights from the Science family of journals.

9.
In Science Journals.
Grocholski, Brent; Suleymanov, Yury; Lopez, Bianca; Yeston, Jake S; Szuromi, Phil; Kelly, Priscilla N; Foley, John F; Ross, Sarah H; Nusinovich, Yevgeniya; Smith, Keith T; Osborne, Ian S; Isles, Hannah M; Malo, Courtney.
Science ; 383(6680): 269-271, 2024 Jan 19.
Artículo en Inglés | MEDLINE | ID: mdl-38236979

RESUMEN

Highlights from the Science family of journals.

10.
In Science Journals.
Lopez, Bianca; Kelly, Priscilla N; Yeston, Jake S; Lavine, Marc S; Szuromi, Phil; Vignieri, Sacha; Wong, Wei; Scanlon, Seth Thomas; Stern, Peter; Osborne, Ian S; Grocholski, Brent; Malo, Courtney.
Science ; 383(6679): 159-160, 2024 Jan 12.
Artículo en Inglés | MEDLINE | ID: mdl-38207042

RESUMEN

Highlights from the Science family of journals.

11.
In Science Journals.
Jiang, Di; Yeston, Jake S; Isles, Hannah M; Ray, L Bryan; Smith, H Jesse; Grocholski, Brent; Stajic, Jelena; Foley, John F; Simonti, Corinne; Funk, Michael A; Vignieri, Sacha; Smith, Keith T; Scanlon, Seth Thomas; Malo, Courtney.
Science ; 382(6674): 1009-1011, 2023 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-38033083

RESUMEN

Highlights from the Science family of journals.

12.
In Science Journals.
Osborne, Ian S; Seale, Madeleine; Foley, John F; Stajic, Jelena; Funk, Michael A; Hurtley, Stella M; Fogg, Christiana N; Malo, Courtney; Lempriere, Sarah A; Vignieri, Sacha; Stern, Peter; Yeston, Jake S; Isles, Hannah M.
Science ; 382(6669): 413-415, 2023 Oct 27.
Artículo en Inglés | MEDLINE | ID: mdl-37883567

RESUMEN

Highlights from the Science family of journals.

13.
In Science Journals.
Funk, Michael A; Wong, Wei; Vignieri, Sacha; Stajic, Jelena; Ash, Caroline; Malo, Courtney S; Isles, Hannah M; Hurtley, Stella M; Grocholski, Brent; Stern, Peter; Szuromi, Phil.
Science ; 382(6666): 64-66, 2023 Oct 06.
Artículo en Inglés | MEDLINE | ID: mdl-37797013

RESUMEN

Highlights from the Science family of journals.

14.
In Science Journals.
Scanlon, Seth Thomas; Smith, Keith T; Yeston, Jake; Lavine, Marc S; Lopez, Bianca; Malo, Courtney; VanHook, Annalisa M; Uzogara, Ekeoma; Hurtley, Stella M; Kelly, Priscilla N; Grocholski, Brent; Maroso, Mattia; Isles, Hannah M.
Science ; 381(6662): 1061-1063, 2023 Sep 08.
Artículo en Inglés | MEDLINE | ID: mdl-37676937

RESUMEN

Highlights from the Science family of journals.

15.
In Science Journals.
Smith, Keith T; Suleymanov, Yury; Szuromi, Phil; Smith, H Jesse; Maroso, Mattia; Olingy, Claire; Malo, Courtney; Funk, Michael A; Vignieri, Sacha; Scanlon, Seth Thomas; Nusinovich, Yevgeniya; Osborne, Ian S; Jiang, Di; Lavine, Marc S; Foley, John F; Lempriere, Sarah A.
Science ; 381(6659): 743-745, 2023 Aug 18.
Artículo en Inglés | MEDLINE | ID: mdl-37590337

RESUMEN

Highlights from the Science family of journals.

16.
In Science Journals.
Smith, H Jesse; Jiang, Di; Stajic, Jelena; Yeston, Jake; Fogg, Christiana N; Malo, Courtney S; Ash, Caroline; Simonti, Corinne; Scanlon, Seth Thomas; Szuromi, Phil; Lavine, Marc S; VanHook, Annalisa M; Grocholski, Brent.
Science ; 381(6655): 280-282, 2023 Jul 21.
Artículo en Inglés | MEDLINE | ID: mdl-37471541

RESUMEN

Highlights from the Science family of journals.

17.
In Science Journals.
Lopez, Bianca; Lavine, Marc S; Hurtley, Stella M; Yeston, Jake; Jiang, Di; Stajic, Jelena; Ferrarelli, Leslie K; Malo, Courtney S; Seale, Maddy; Szuromi, Phil; Fogg, Christiana N.
Science ; 381(6653): 39-40, 2023 Jul 07.
Artículo en Inglés | MEDLINE | ID: mdl-37410816

RESUMEN

Highlights from the Science family of journals.

18.
In Science Journals.
Lopez, Bianca; Vignieri, Sacha; Osborne, Ian S; Yeston, Jake; Jiang, Di; Suleymanov, Yury; Grocholski, Brent; Malo, Courtney S; Kelly, Priscilla N; Scanlon, Seth Thomas; Ray, L Bryan; Smith, Keith T; Ferrarelli, Leslie K; Smith, H Jesse; Olingy, Claire.
Science ; 380(6649): 1024-1025, 2023 Jun 09.
Artículo en Inglés | MEDLINE | ID: mdl-37289882

RESUMEN

Highlights from the Science family of journals.

19.
IL-27 induces an IFN-like signature in murine macrophages which in turn modulate colonic epithelium.
Andrews, Caroline; McLean, Mairi H; Hixon, Julie A; Pontejo, Sergio M; Starr, Tregei; Malo, Courtney; Cam, Margaret; Ridnour, Lisa; Hickman, Heather; Steele-Mortimer, Olivia; Wink, David A; Young, Howard A; McVicar, Daniel W; Li, Wenqing; Durum, Scott K.
Front Immunol ; 14: 1021824, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37153622

RESUMEN

Mucosal delivery of IL-27 has been shown to have a therapeutic benefit in murine models of inflammatory bowel disease (IBD). The IL-27 effect was associated with phosphorylated STAT1 (pSTAT1), a product of IL27 receptor signaling, in bowel tissue. To determine whether IL-27 acted directly on colonic epithelium, murine colonoids and primary intact colonic crypts were shown to be unresponsive to IL-27 in vitro and to lack detectable IL-27 receptors. On the other hand, macrophages, which are present in inflamed colon tissue, were responsive to IL-27 in vitro. IL-27 induced pSTAT1 in macrophages, the transcriptome indicated an IFN-like signature, and supernatants induced pSTAT1 in colonoids. IL-27 induced anti-viral activity in macrophages and MHC Class II induction. We conclude that the effects of mucosal delivery of IL-27 in murine IBD are in part based on the known effects of IL27 inducing immunosuppression of T cells mediated by IL-10. We also conclude that IL-27 has potent effects on macrophages in inflamed colon tissue, generating mediators that in turn act on colonic epithelium.


Asunto(s)
Enfermedades Inflamatorias del Intestino , Interleucina-27 , Ratones , Animales , Interleucina-27/uso terapéutico , Colon , Enfermedades Inflamatorias del Intestino/tratamiento farmacológico , Macrófagos , Epitelio
20.
In Science Journals.
Vignieri, Sacha; Simonti, Corinne; Seale, Maddy; Hurtley, Stella M; Smith, H Jesse; Stajic, Jelena; Malo, Courtney S; Wong, Wei; Szuromi, Phil; Alderton, Gemma; Grocholski, Brent; Lopez, Bianca; Fogg, Christiana N.
Science ; 380(6647): 808-809, 2023 May 26.
Artículo en Inglés | MEDLINE | ID: mdl-37228196

RESUMEN

Highlights from the Science family of journals.

ENVIAR RESULTADO:
Email
Exportar
Imprimir
RSS
XML
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA