RESUMEN
We used specific histochemical fluorescence-microscopic method of visualization of catecholamines to study adrenergic innervation of the thyroid gland tissue, blood vessels of the thyroid gland, cervical lymphatic vessel and lymph nodes in rats during correction of hypothyroidism with a bioactive formulation (Vozrozhdenie Plus balm with Potentilla alba L.). In experimental hypothyroidism, adrenergic innervation of the thyroid gland and the wall of the cervical lymph node, concentrated mainly along the arterial vessels and the cervical lymphatic vessel, retained its structural formations (plexuses and varicosities), but diffusion of catecholamines outside these formations was observed. Correction with the bioactive formulation restored of the contours of the nerve plexuses and varicosities and their brighter fluorescence in the thyroid gland and cervical lymphatic vessel and node. During correction of hypothyroidism with the bioactive formulation, reorganization of regional lymphatic vessels and nodes was more pronounced than reorganization of the thyroid gland.
Asunto(s)
Hipotiroidismo , Ganglios Linfáticos/patología , Vasos Linfáticos/patología , Glándula Tiroides/irrigación sanguínea , Glándula Tiroides/inervación , Fibras Adrenérgicas/efectos de los fármacos , Fibras Adrenérgicas/patología , Fibras Adrenérgicas/ultraestructura , Animales , Vasos Sanguíneos/diagnóstico por imagen , Vasos Sanguíneos/efectos de los fármacos , Vasos Sanguíneos/patología , Hipotiroidismo/diagnóstico por imagen , Hipotiroidismo/tratamiento farmacológico , Hipotiroidismo/patología , Ganglios Linfáticos/diagnóstico por imagen , Ganglios Linfáticos/efectos de los fármacos , Vasos Linfáticos/diagnóstico por imagen , Vasos Linfáticos/efectos de los fármacos , Masculino , Microscopía Fluorescente , Extractos Vegetales/farmacología , Extractos Vegetales/uso terapéutico , Yoduro de Potasio/farmacología , Yoduro de Potasio/uso terapéutico , Ratas , Glándula Tiroides/diagnóstico por imagen , Glándula Tiroides/efectos de los fármacos , Hormonas Tiroideas/farmacología , Hormonas Tiroideas/uso terapéuticoRESUMEN
Adrenergic innervation in the tissue of the thyroid gland, blood vessels of the thyroid gland, cervical lymphatic vessel, and lymph nodes in rats with hypothyroidism was studied by using a specific histochemical fluorescent-microscopic method of visualization of catecholamines. The presence of adrenergic innervation in the blood and lymph vessels and nodes was demonstrated. In hypothyroidism, diffusion of norepinephrine from nerve fibers and varicose thickenings was observed in the wall of the upper and lower thyroid arteries and adjacent cervical lymphatic vessels and nodes.