Enhancement of MXene optical properties towards medical applications via metal oxide incorporation.

MXenes have garnered research attention in the field of biomedical applications due to their unique properties, such as a large surface area, low toxicity, biocompatibility, and stability. Their optical behavior makes them versatile for a wide range of biomedical applications, from diagnostics to therapeutics. Nonetheless, MXenes have some minor limitations, including issues with restacking, susceptibility to oxidation, and a non-semiconducting nature. These limitations have prompted researchers to explore the incorporation of metal oxides into MXene structures. Metal oxides possess advantageous properties such as a high surface area, biocompatibility, intriguing redox behavior, catalytic activity, semiconducting properties, and enhanced stability. Incorporating metal oxides into MXenes can significantly improve their conductivity, surface area, and mechanical strength. In this review, we emphasize the importance of incorporating metal oxides into MXenes for light-influenced biomedical applications. We also provide insights into various preparation methods for incorporating metal oxides into MXene structures. Furthermore, we discuss how the incorporation of metal oxides enhances the optical behavior of MXenes. Finally, we offer a glimpse into the future potential of metal oxide-incorporated MXenes for diverse biomedical applications.

Cerium-based metal sulfide derived nanocomposite-embedded rGO as an efficient catalyst for photocatalytic application.

Reduced graphene oxide (rGO) with metal sulfides is an efficient photocatalyst for treating textile effluent. Herein, a hydrothermal technique was used to synthesize transition metal sulfide with rGO nanocomposite. Under 120 min of sunlight exposure, the cerium-nickel sulfide/rGO nanocomposite (Ce2S3-NiS2/rGO) photodegraded the methyl orange (MO) dye with an efficiency of 89.1% which is significantly higher than that of bare nickel sulfide (NiS2) and cerium sulfide (Ce2S3) photocatalysts. Moreover, another model pollutant dye bromophenol blue (BP) was treated under the same experimental condition, and it has achieved about 84.2% degradation efficiency. The combination of NiS2 and Ce2S3 improves the separation efficiency of photogenerated carriers, resulting in improved photocatalytic activity. In addition, ternary metal sulfide with rGO increases pollutant adsorption and electron-hole photogenerated pairs. Therefore, the mechanism of photocatalytic Ce2S3-NiS2/rGO is investigated in detail. This research could pave the way for the development of capable and adaptable Ce2S3-NiS2/rGO photocatalysts for environmental remediation.

Facile synthesis and defect optimization of 2D-layered MoS2 on TiO2 heterostructure for industrial effluent, wastewater treatments.

Current research is paying much attention to heterojunction nanostructures. Owing to its versatile characteristics such as stimulating morphology, affluent surface-oxygen-vacancies and chemical compositions for enhanced generation of reactive oxygen species. Herein, we report the hydrothermally synthesized TiO2@MoS2 heterojunction nanostructure for the effective production of photoinduced charge carriers to enhance the photocatalytic capability. XRD analysis illustrated the crystalline size of CTAB capped TiO2, MoS2@TiO2 and L-Cysteine capped MoS2@TiO2 as 12.6, 11.7 and 10.2 nm, respectively. The bandgap of the samples analyzed by UV-Visible spectroscopy are 3.57, 3.66 and 3.94 eV. PL spectra of anatase phase titania shows the peaks present at and above 400 nm are ascribed to the defects in the crystalline structure in the form of oxygen vacancies. HRTEM reveals the existence of hexagonal layered MoS2 formation on the spherical shaped TiO2 nanoparticles at the interface. X-ray photoelectron spectroscopy recommends the chemical interactions between MoS2 and TiO2, specifically, oxygen vacancies. In addition, the electrochemical impedance spectroscopy studies observed that L-MT sample performed low charge transfer resistance (336.7 Ω cm2) that promotes the migration of electrons and interfacial charge separation. The photocatalytic performance is evaluated by quantifying the rate of Congo red dye degradation under visible light irradiation, and the decomposition efficiency was found to be 97%. The electron trapping recombination and plausible photocatalytic mechanism are also explored, and the reported work could be an excellent complement for industrial wastewater treatment.

Engineering of 2D transition metal carbides and nitrides MXenes for cancer therapeutics and diagnostics.

The 2D layered structured material with unique surface terminations and properties have showed great potential in variety of biomedical research fields including drug delivery and cancer therapeutics which forms the major focus of this review. MXenes as a multifunctional two-dimensional (2D) nanomaterial, has also received momentous research interest in oncology resulting from its intriguing structure and fascinating properties of magnetism and photodynamic properties such as luminescent, conductivity, magnetism, non-toxicity and its bio compatibility. This reported review intends to cover exclusively the synthesis and utilization of MXenes in oncological applications, and subsequently its future outlook in cancer therapeutic, diagnostic and theranostics. The versatile and unique physio-chemistry of MXenes permits fine tuning of its properties towards oncological applications ranging from the cancer therapeutic (e.g., photothermal therapy, photodynamic therapy, radiation therapy, chemotherapy) to cancer imaging (e.g., CT/MRI/PA imaging) as well as cancer theranostic applications. We have started the discussion by portraying the broad picture of physio-chemical aspects of MXenes followed by its drug delivery functionalities. Subsequently, ROS mediated therapeutic strategies of photodynamic therapy and radiotherapy as well as light triggered functionalities of MXenes were detailed comprehensively. In the middle of the gallery, various imaging and sensing aspects of MXenes were elucidated. Finally, we have concluded by explaining the combined therapy and diagnostic functions (theranostics) of MXenes. To put it in perspective, the current challenges and new opportunities in MXenes also discussed will give great realistic insights to motivate further research in realizing MXene as an intelligent oncological tool.