RESUMEN
Odontogenic myxoma (OM) is a mesenchymal tissue benign neoplasia, being relatively rare which is almost exclusively seen in tooth-bearing areas. OM commonly occurs in the 2(nd) and 3(rd) decade and the mandible is involved more commonly than the maxilla. The lesion often grows without symptoms and presents as a painless swelling. Radiographically, the myxoma appears as a unilocular or multilocular radiolucency. This article presents a rare case of OM occurring in the maxilla of a 28-year-old female patient with a brief review of the literature.
RESUMEN
BACKGROUND: The effect of inflammation on pathogenesis and biological behavior of odontogenic keratocyst (OKC) and dentigerous cyst (DC) is not completely understood. Hence, we aimed to analyze the effect of inflammation on biological behavior of OKC and DC using a proliferative and anti-apoptotic marker, i.e., proliferative cellular nuclear antigen (PCNA) and Bcl-2, respectively. MATERIALS AND METHODS: Immunohistochemical staining was performed using anti-PCNA and Bcl-2 antibody in 10 cases each of classical OKC, inflamed OKC and classical DC and inflamed DC. RESULTS: Inflamed OKC and DC showed a significant increase in PCNA expression and decrease in Bcl-2 expression when compared with non-inflamed cyst. Correlation between inflammation and proliferative and anti-apoptotic activity was found to be statistically non-significant. CONCLUSION: Inflammation is responsible for change in behavior of neoplastic epithelium of OKC and hence should be treated meticulously, whereas in DC it is responsible for changes in the epithelial lining.
RESUMEN
UNLABELLED: HISTORY AND OBJECTIVE: The aim of this study was to study the anxiolytic effects of Ocimum sanctum stress-induced anxiety. MATERIALS AND METHODS: The study was carried out using male albino rats (200 ± 50 gm), male albino mice (25 ± 100) the effect of O. sanctum evaluated for anxiety and depression using forced swim test FST and rotarod test. RESULTS: Restraint stress (3 hours/day for six consecutive days) induced a significant reduction. It was significantly decreases the mobility period during stress. The standard deviation values are 14.4 and 9.26 and is statistically significant (p = 0.001). In rotarod test, (a) increased latency and (b) decreased ambulation and rearing were also reversed by O. sanctum. A significant increase in immobility period was observed in FST and TST after restraint stress. O. sanctum and C. sinensis significantly reduced the immobility times of rats in FST and TST. CONCLUSION: Ocimum sanctum possess significant antistress activity but the magnitude and efficacy for relieving stress is less, when compare to standard anxiolytic agent, i.e. Alprazolam.