RESUMEN
We studied the content of neuron-specific enolase (NSE) in 69 paired samples of blood serum and seminal plasma from men with azoospermia (n=11) and oligoastenozoospermia (n=10) and from men with fertile ejaculate (n=48). NSE concentration was determined by ELISA (Vector-Best kit). The median concentration and the interquartile range of the NSE content in seminal plasma were 65.7 (47.9; 83.4) ng/ml and 24.33 times (Ñ<0.000001) exceeded those for blood serum 2.7 (1.45; 4.0) ng/ml. There were no differences in the content of NSE between the groups for both seminal plasma and blood serum. The content of NSE in seminal plasma did not correlate with the content of NSE in blood serum, and also did not depend on the content of spermatozoa. A weak negative correlation (r=-0.341; p=0.0057) was found between the age of the examinees and the level of NSE in seminal plasma, but not in blood serum.
Asunto(s)
Semen , Suero , Ensayo de Inmunoadsorción Enzimática , Humanos , Masculino , Fosfopiruvato Hidratasa/análisis , Semen/química , Suero/química , EspermatozoidesRESUMEN
Modern methods of diagnosis of chronic viral hepatitis used in the practice of the military-medical examination. The article presents current views on the classification of chronic viral hepatitis. The characteristic of methodical diagnostic approaches is presented: The attention to the etiological pathology verification is paid. The results of study on clinical characteristics of patients with chronic viral hepatitis are used as the basis for the developed criteria for evaluating fitness for military service.
Asunto(s)
Hepatitis Viral Humana/clasificación , Hepatitis Viral Humana/diagnóstico , Medicina Militar/métodos , Enfermedad Crónica , Femenino , Humanos , MasculinoRESUMEN
The authors showed that at the present time military much more servicemen, suffering from obstructive pulmonary disease, may receive medical examination in outpatient conditions. Series of researches allow us to perform a medical examination on an outpatient basis. The calculation of the cost-effectiveness of health services to such patients during a military medical examination in the hospital and clinics was made. Savings during the examination in the clinic for 1 patient was 2829 rubbles.
Asunto(s)
Atención Ambulatoria , Testimonio de Experto , Medicina Militar , Personal Militar , Enfermedad Pulmonar Obstructiva Crónica/diagnóstico , Adulto , Anciano , Atención Ambulatoria/economía , Atención Ambulatoria/organización & administración , Atención Ambulatoria/tendencias , Análisis Costo-Beneficio , Testimonio de Experto/economía , Testimonio de Experto/métodos , Humanos , Persona de Mediana Edad , Medicina Militar/economía , Medicina Militar/organización & administración , Medicina Militar/tendencias , Enfermedad Pulmonar Obstructiva Crónica/clasificación , Pruebas de Función Respiratoria , Federación de Rusia , Encuestas y CuestionariosRESUMEN
Introduction of the multilevel system of medical care to the patient with stroke in the Tatarstan Republic for 2008-2012 and formation of vascular centers are analyzed. There is a positive trend in some indices (stroke morbidity, treatment efficacy, fatality, number of functionally independent patients etc).
Asunto(s)
Atención a la Salud/métodos , Servicios Médicos de Urgencia/métodos , Accidente Cerebrovascular/terapia , Femenino , Humanos , Masculino , Morbilidad/tendencias , Estudios Retrospectivos , Federación de Rusia/epidemiología , Accidente Cerebrovascular/epidemiología , Resultado del TratamientoRESUMEN
The typical changes of hemostasis indicators in different periods of gestation are described. The analysis of blood plasma in pregnant women with menace of miscarriage and compromised anamnestic record on spontaneous or attempted abortion was made. The valid hypercoagulation deviations are detected. They are manifested in the decrease of international normalized ratio indicators and index of activated partial thromboplastin time, the increase of level of soluble fibrin-monomeric complex against the background of mild hyperfibrinogenemia and decrease of activity of plasminogen, antihtrombin III and protein C. The lupousus anticoagulant and Leiden mutation occurred more often. The evidence of changes differed depending of presence of complications in the anamnesis and current menace of miscarriage. The established thrombofilic shifts can play certain pathogenic role in development of noncarrying of pregnancy.
Asunto(s)
Aborto Espontáneo/sangre , Hemostasis , Complicaciones Hematológicas del Embarazo/sangre , Aborto Espontáneo/genética , Aborto Espontáneo/fisiopatología , Adolescente , Adulto , Factores de Coagulación Sanguínea/genética , Factores de Coagulación Sanguínea/metabolismo , Femenino , Humanos , Persona de Mediana Edad , Tiempo de Tromboplastina Parcial , Embarazo , Complicaciones Hematológicas del Embarazo/genética , Complicaciones Hematológicas del Embarazo/fisiopatología , Trombofilia/sangre , Trombofilia/genética , Trombofilia/fisiopatologíaRESUMEN
The article deals with efficiency of the course of O2-Xe inhalation for correction of the functional state of deck aviation pilots in a long march. The course was shown to stabilize vagosympathetic balance in organism, to compensate functioning and to retain reserve of the cardiovascular system that resulted in significant psychoemotional animation attested by self-appreciation, amelioration and cheerfulness, and weakening of reactive anxiety. These observations point to applicability of xenon-based gas mixtures to correction of the pilot's functional state in the most intensive periods of service. Guidelines for broad adoption of the method by military medicine have been developed.
Asunto(s)
Personal Militar , Xenón/administración & dosificación , Administración por Inhalación , Adulto , Medicina Aeroespacial , Afecto/efectos de los fármacos , Sistema Cardiovascular/efectos de los fármacos , Humanos , Masculino , Oxígeno/administración & dosificación , Oxígeno/uso terapéutico , Aptitud Física , Sistema Nervioso Simpático/efectos de los fármacosRESUMEN
The efficiency of applying precision devices and multiple laboratory methods devised to reveal the causes of bleeding and thromboses significantly depends on whether a wide range of rules of the preanalytical stage of the study is observed. The paper gives detailed information on conditions for taking blood samples, their transport, and preparation for examination of the hemostatic system. The given information is based on the worldwide recommendations and many years' experience gained by the authors at the laboratory of hemostasis.
Asunto(s)
Trastornos de la Coagulación Sanguínea/diagnóstico , Trastornos de la Coagulación Sanguínea/tratamiento farmacológico , Trastornos de la Coagulación Sanguínea/patología , Trastornos de la Coagulación Sanguínea/fisiopatología , Recolección de Muestras de Sangre/métodos , Recolección de Muestras de Sangre/normas , Hemorragia , Hemostasis/efectos de los fármacos , Hemostáticos/uso terapéutico , Humanos , Guías de Práctica Clínica como Asunto , TrombosisRESUMEN
The article deals with the data concerning DNA-citometry of peripheral blood cells in healthy children and under particular pathologic conditions. The causes of shifts are discussed as their possible role in pathogenesis and clinical diagnostics of diseases as well.
Asunto(s)
Células Sanguíneas , ADN/sangre , Citometría de Imagen/métodos , Adolescente , Aneuploidia , Células Sanguíneas/citología , Células Sanguíneas/metabolismo , Neoplasias Encefálicas/sangre , Neoplasias Encefálicas/diagnóstico , Neoplasias Encefálicas/genética , Ciclo Celular , Niño , Preescolar , Glomerulonefritis/sangre , Glomerulonefritis/diagnóstico , Glomerulonefritis/genética , Humanos , Lactante , Enfermedades Urológicas/sangre , Enfermedades Urológicas/diagnóstico , Enfermedades Urológicas/genéticaRESUMEN
The article gives an experimental assessment of processes of healing anastomoses of hollow organs using preparation "Enterosan". "Enterosan" decreases inflammatory alterations and accelerates processes of reparative regeneration in the anastomosis zone.
Asunto(s)
Duodeno/cirugía , Glicosaminoglicanos/uso terapéutico , Cicatrización de Heridas/efectos de los fármacos , Administración Oral , Anastomosis Quirúrgica , Animales , Modelos Animales de Enfermedad , Duodeno/fisiología , Estudios de Seguimiento , Glicosaminoglicanos/administración & dosificación , Humanos , Masculino , Ratas , Ratas WistarRESUMEN
The analysis of enterosan influence on intestinal anastomosis healing in 90 rats was carried out. The medication is highly active as a regeneration stimulator. The use of enterosan decreases inflammation and activates regeneration in anastomosis area.
Asunto(s)
Enfermedades Gastrointestinales/cirugía , Glicosaminoglicanos/farmacología , Glicosaminoglicanos/uso terapéutico , Complicaciones Posoperatorias/prevención & control , Anastomosis Quirúrgica , Animales , Enfermedad Celíaca/tratamiento farmacológico , Mucosa Intestinal/efectos de los fármacos , Ratas , Ratas WistarRESUMEN
Statistical analysis has established the importance and adequacy of determination of the levels of circulating immune complexes, leukocytes, and HLA-DR+ lymphocytes for the prediction of the outcome of treatment for surgical sepsis. A model of prognostically best clinical outcome of the disease was used to calculate the ranges of values of immunological parameters in which it is expedient to use immunovenin, imunofan, inferon, roncoleukin, and ceruloplasmin in order to have an optimal clinical effect; moreover, there was a 76% agreement of the actual results of treatment with calculated ones.
Asunto(s)
Factores Inmunológicos/administración & dosificación , Modelos Teóricos , Complicaciones Posoperatorias/sangre , Complicaciones Posoperatorias/terapia , Sepsis/sangre , Sepsis/terapia , Adolescente , Adulto , Anciano , Complejo Antígeno-Anticuerpo/sangre , Complejo Antígeno-Anticuerpo/inmunología , Femenino , Antígenos HLA-DR/sangre , Antígenos HLA-DR/inmunología , Humanos , Recuento de Leucocitos , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias/inmunología , Complicaciones Posoperatorias/mortalidad , Sepsis/inmunología , Sepsis/mortalidad , Resultado del TratamientoRESUMEN
The investigation determined whether there was a relationship of thyroid diseases with the geology of the place of residence and its associated spectrum of trace elements (iron, chromium, selenium, manganese, cobalt, copper, nickel, arsenic, and zinc). The geologo-geomorphological factors of the habitat, such as geological formations (mineral composition, structure, the degree of rock metamorphism), tectonics, the history of geological development, relief, paleorelief, were found to be of considerable importance in the formation of the human trace element status. Both deficiency and excess of trace elements was shown to be of pathogenetic value in the development of thyroid diseases. Residence in the area wherein carbonate rocks are predominant contributes to an increase in incidence of thyroid diseases.
Asunto(s)
Bocio Endémico/epidemiología , Cabello/química , Oligoelementos/análisis , Ecosistema , Bocio Endémico/etiología , Humanos , Federación de Rusia/epidemiologíaRESUMEN
We studied the functional and metabolic changes of erythrocytes in systemic vasculitis (SV). The below was detected: an increasing intensity of blood chemiluminescence, a higher concentration of TBA-positive substances in erythrocyte membranes, inhibited Na+, K+ - and Ca2+ -activated and Mg2+ -related ATPases in erythrocytes and a reduced osmotic and acidic resistance of erythrocytes. An enhanced aggregation ability of erythrocytes and their inhibited desagregation were observed in hemorrhagic vasculitis an especially in microscopic polyangiitis. The revealed changes characterize the significance of the erythrocyte pathology in thrombosis and development of hemorrhagic disorders in SV patients.
Asunto(s)
Agregación Eritrocitaria , Eritrocitos/metabolismo , Vasculitis/sangre , Adolescente , Adulto , Anciano , ATPasa de Ca(2+) y Mg(2+)/metabolismo , Membrana Eritrocítica/enzimología , Membrana Eritrocítica/metabolismo , Eritrocitos/enzimología , Femenino , Radicales Libres/metabolismo , Humanos , Masculino , Persona de Mediana Edad , Fragilidad Osmótica , ATPasa Intercambiadora de Sodio-Potasio/metabolismo , Vasculitis/enzimología , Vasculitis/metabolismoAsunto(s)
Aborto Retenido/sangre , Citocinas/sangre , Adolescente , Adulto , Femenino , Humanos , EmbarazoRESUMEN
Data on the impact exerted by industrial products, i.e. pyromellitic dianhydride, on the acidic and osmotic resistance of erythrocytes in workers are described. The influence of hazardous factors of the oil-and-chemical production was found to result in a changing erythrocytes' resistance (of workers) to the osmotic and acidic hemolytics with regard for a labor record and duration of contact with toxicants. The shifts in acidic and osmotic resistance can serve as an early marker of changes in the functional erythron's status in workers occupied under hazardous industrial factors.