Effect of Age and Acute Exercise on Circulating Angioregulatory Factors.

The balance of angiogenic factors, including vascular endothelial growth factor (VEGF), and angiostatic factors, like thrombospondin-1 (TSP-1) and endostatin, controls striated muscle angiogenic responses to exercise training. The effect of age on circulating levels of these factors following a bout of exercise is unclear. The authors hypothesized that older adults would have lower circulating VEGF but higher TSP-1 and endostatin after exercise compared with young adults. Ten young and nine older participants cycled for 45 min at 60% estimated HRmax. Serum [VEGF], [TSP-1], and [endostatin] obtained before (PREX), immediately after (POSTX0), and 3 hr after (POSTX3) exercise were analyzed. [VEGF] increased in older adults only from PREX to POSTX0 (p < .05). [TSP-1] increased in both age groups (p < .05). There was no effect of age or exercise on [endostatin]. In conclusion, immediately after exercise, both groups had a similar increase in [TSP-1], but [VEGF] increased in older adults only.

Somatosensory Perception of Running Shoe Mass may be influenced by Extended Wearing Time or Inclusion of a Personal Reference Shoe, Depending on Testing Method.

Consumers may purchase running shoes on the basis of their masses, yet little is known about shoe mass perceptual abilities. In this multi-part experiment, four groups of twenty-five young adult males (total n = 100) were challenged to gauge the relative masses of five unfamiliar running shoes. The four groups differed by the length of time they were given to wear the shoes (up to 1 minute versus 5 minutes) and whether or not they were able to use their own personal running shoes as a reference. After wearing each individual pair of shoes, participants provided perceived comfort and heaviness rankings using visual analogue scales (VAS). After wearing all five pairs of unfamiliar shoes, participants gave a verbal ranking of relative shoe mass. Participants also hefted the shoes with their hands and positioned them in order of relative mass. Extended wearing time improved overall verbal ranking accuracy, but did not improve mass perception accuracy as determined by comparing VAS heaviness rankings to actual shoe masses. Conversely, use of a personal reference shoe improved mass perception accuracy as determined by comparing VAS heaviness rankings to actual shoe masses, but did not improve overall verbal ranking accuracy. Hand perceptual scores were similar across the four groups, likely due to a ceiling effect. VAS comfort scores were unrelated to shoe masses. The results suggest that wearing time and reference shoes may influence mass perception by the lower limb in a context-specific manner.