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1.
Phys Rev Lett ; 123(11): 113604, 2019 Sep 13.
Artículo en Inglés | MEDLINE | ID: mdl-31573265

RESUMEN

In this Letter, we investigate the effect of orbital angular momentum (OAM) on elastic photon-photon scattering in a vacuum for the first time. We define exact solutions to the vacuum electromagnetic wave equation which carry OAM. Using those, the expected coupling between three initial waves is derived in the framework of an effective field theory based on the Euler-Heisenberg Lagrangian and shows that OAM adds a signature to the generated photons thereby greatly improving the signal-to-noise ratio. This forms the basis for a proposed high-power laser experiment utilizing quantum optics techniques to filter the generated photons based on their OAM state.

2.
Phys Rev Lett ; 122(25): 254801, 2019 Jun 28.
Artículo en Inglés | MEDLINE | ID: mdl-31347867

RESUMEN

As an alternative to Compton backscattering and bremsstrahlung, the process of colliding high-energy electron beams with strong laser fields can more efficiently provide both a cleaner and brighter source of photons in the multi-GeV range for fundamental studies in nuclear and quark-gluon physics. In order to favor the emission of high-energy quanta and minimize their decay into electron-positron pairs, the fields must not only be sufficiently strong, but also well localized. We here examine these aspects and develop the concept of a laser-particle collider tailored for high-energy photon generation. We show that the use of multiple colliding laser pulses with 0.4 PW of total power is capable of converting more than 18% of multi-GeV electrons passing through the high-field region into photons, each of which carries more than half of the electron initial energy.

3.
Rev Sci Instrum ; 89(11): 113303, 2018 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-30501337

RESUMEN

We present a design for a pixelated scintillator based gamma-ray spectrometer for non-linear inverse Compton scattering experiments. By colliding a laser wakefield accelerated electron beam with a tightly focused, intense laser pulse, gamma-ray photons up to 100 MeV energies and with few femtosecond duration may be produced. To measure the energy spectrum and angular distribution, a 33 × 47 array of cesium-iodide crystals was oriented such that the 47 crystal length axis was parallel to the gamma-ray beam and the 33 crystal length axis was oriented in the vertical direction. Using an iterative deconvolution method similar to the YOGI code, modeling of the scintillator response using GEANT4 and fitting to a quantum Monte Carlo calculated photon spectrum, we are able to extract the gamma ray spectra generated by the inverse Compton interaction.

4.
Clin Nutr ; 37(6 Pt A): 2001-2010, 2018 12.
Artículo en Inglés | MEDLINE | ID: mdl-29032841

RESUMEN

BACKGROUND & AIMS: Alcohol consumption is considered to affect circulating fatty acids (FAs) but knowledge about specific associations is limited. We aimed to assess the relation between alcohol consumption and serum FAs in 60-year-old Swedish men and women. METHODS: In a random sample of 1917 men and 2058 women residing in Stockholm county, cross-sectional associations between different categories of alcohol consumption and FAs were assessed using linear regression; ß1 coefficients with 95% confidence interval (CI) were calculated. Self-reported alcohol consumption was categorized as none, low (≤9.9 g/day) (reference), moderate (10-29.9 g/day) and high (≥30 g/day). Moderate alcohol consumption was further subdivided into consumption of beer, wine, liquor and their combinations. Thirteen serum cholesterol ester FAs were measured by gas chromatography and individual FAs were expressed as percentage of total FAs. RESULTS: Increasing alcohol consumption was associated to linear increase of saturated myristic acid, monounsaturated FAs and n-6 polyunsaturated (PUFA) arachidonic acid, whereas linear decrease was noted for saturated pentadecanoic acid and for n-6 PUFA linoleic acid. With non-linear associations, increasing alcohol consumption also associated to decreased saturated stearic acid, n-6 PUFA dihomo-gamma-linolenic acid, and n-3 PUFA docosahexaenoic acid and increased saturated palmitic acid, n-6 PUFA gamma-linolenic acid and n-3 PUFA eicosapentaenoic acid. Among types of beverages, wine consumption was associated with n-6 PUFA arachidonic acid (ß1 0.59; 95% CI: 0.30;0.88) and the n-3 PUFAs eicosapentaenoic acid (ß1 0.54; 95% CI: 0.30;0.78), and docosahexaenoic acid (ß1 0.06; 95% CI: 0.00;0.12). CONCLUSIONS: These findings may give important basis for further investigations to better understand biological mechanisms behind the dose-dependent associations between alcohol consumption and health outcomes observed in many previous studies.


Asunto(s)
Consumo de Bebidas Alcohólicas/sangre , Consumo de Bebidas Alcohólicas/epidemiología , Ácidos Grasos/sangre , Bebidas Alcohólicas/estadística & datos numéricos , Estudios Transversales , Femenino , Humanos , Masculino , Persona de Mediana Edad , Suecia/epidemiología
5.
Curr Sleep Med Rep ; 3(3): 143-151, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-28955651

RESUMEN

PURPOSE OF REVIEW: The majority of the adult population is affected by obstructive sleep apnea (OSA), according to recent epidemiological research. Oral appliance (OA) therapy is increasingly recommended, particularly for patients with milder OSA. This review updates the evidence in favor of OA therapy. RECENT FINDINGS: A high level of evidence shows that OA is effective in the treatment of OSA, but continuous positive airway pressure (CPAP) is more efficient. Higher adherence with OAs may compensate for this difference. Daytime sleepiness is better treated with CPAP than with OA in patients with severe OSA. In patients with milder OSA, it is unclear whether sleepiness is significantly reduced. The long-term effectiveness of OAs is uncertain because of side-effects and the risk of OSA deterioration. SUMMARY: OAs are effective, but their efficacy is more variable than that of CPAP. More research is needed about the mechanism of action of OA, subjective effects and long-term health outcomes.

6.
Phys Rev Lett ; 118(15): 154803, 2017 Apr 14.
Artículo en Inglés | MEDLINE | ID: mdl-28452504

RESUMEN

The interaction of charged particles and photons with intense electromagnetic fields gives rise to multiphoton Compton and Breit-Wheeler processes. These are usually described in the framework of the external field approximation, where the electromagnetic field is assumed to have infinite energy. However, the multiphoton nature of these processes implies the absorption of a significant number of photons, which scales as the external field amplitude cubed. As a result, the interaction of a highly charged electron bunch with an intense laser pulse can lead to significant depletion of the laser pulse energy, thus rendering the external field approximation invalid. We provide relevant estimates for this depletion and find it to become important in the interaction between fields of amplitude a_{0}∼10^{3} and electron bunches with charges of the order of 10 nC.

7.
Phys Rev Lett ; 118(10): 105004, 2017 Mar 10.
Artículo en Inglés | MEDLINE | ID: mdl-28339255

RESUMEN

Accelerated charges radiate, and therefore must lose energy. The impact of this energy loss on particle motion, called radiation reaction, becomes significant in intense-laser matter interactions, where it can reduce collision energies, hinder particle acceleration schemes, and is seemingly unavoidable. Here we show that this common belief breaks down in short laser pulses, and that energy losses and radiation reaction can be controlled and effectively switched off by appropriate tuning of the pulse length. This "quenching" of emission is impossible in classical physics, but becomes possible in QED due to the discrete nature of quantum emissions.

8.
Phys Rev Lett ; 117(10): 104801, 2016 Sep 02.
Artículo en Inglés | MEDLINE | ID: mdl-27636480

RESUMEN

We propose a novel mechanism for ion acceleration based on the guided motion of electrons from a thin layer. The electron motion is locked to the moving nodes of a standing wave formed by a chirped laser pulse reflected from a mirror behind the layer. This provides a stable longitudinal field of charge separation, thus giving rise to chirped-standing-wave acceleration of the residual ions of the layer. We demonstrate, both analytically and numerically, that stable proton beams, with energy spectra peaked around 100 MeV, are feasible for pulse energies at the level of 10 J. Moreover, a scaling law for higher laser intensities and layer densities is presented, indicating stable GeV-level energy gains of dense ion bunches, for soon-to-be-available laser intensities.

9.
Artículo en Inglés | MEDLINE | ID: mdl-26382544

RESUMEN

We review common extensions of particle-in-cell (PIC) schemes which account for strong field phenomena in laser-plasma interactions. After describing the physical processes of interest and their numerical implementation, we provide solutions for several associated methodological and algorithmic problems. We propose a modified event generator that precisely models the entire spectrum of incoherent particle emission without any low-energy cutoff, and which imposes close to the weakest possible demands on the numerical time step. Based on this, we also develop an adaptive event generator that subdivides the time step for locally resolving QED events, allowing for efficient simulation of cascades. Further, we present a unified technical interface for including the processes of interest in different PIC implementations. Two PIC codes which support this interface, PICADOR and ELMIS, are also briefly reviewed.

10.
Heredity (Edinb) ; 115(2): 100-7, 2015 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-23188172

RESUMEN

Habitat fragmentation has been shown to disrupt ecosystem processes such as plant-pollinator mutualisms. Consequently, mating patterns in remnant tree populations are expected to shift towards increased inbreeding and reduced pollen diversity, with fitness consequences for future generations. However, mating patterns and phenotypic assessments of open-pollinated progeny have rarely been combined in a single study. Here, we collected seeds from 37 Eucalyptus incrassata trees from contrasting stand densities following recent clearance in a single South Australian population (intact woodland=12.6 trees ha(-1); isolated pasture=1.7 trees ha(-1); population area=10 km(2)). 649 progeny from these trees were genotyped at eight microsatellite loci. We estimated genetic diversity, spatial genetic structure, indirect contemporary pollen flow and mating patterns for adults older than the clearance events and open-pollinated progeny sired post-clearance. A proxy of early stage progeny viability was assessed in a common garden experiment. Density had no impact on mating patterns, adult and progeny genetic diversity or progeny growth, but was associated with increased mean pollen dispersal. Weak spatial genetic structure among adults suggests high historical gene flow. We observed preliminary evidence for inbreeding depression related to stress caused by fungal infection, but which was not associated with density. Higher observed heterozygosities in adults compared with progeny may relate to weak selection on progeny and lifetime-accumulated mortality of inbred adults. E. incrassata appears to be resistant to the negative mating pattern and fitness changes expected within fragmented landscapes. This pattern is likely explained by strong outcrossing and regular long-distance pollen flow.


Asunto(s)
Ecosistema , Eucalyptus/genética , Flujo Génico , Genética de Población , Animales , Aves , ADN de Plantas/genética , Variación Genética , Genotipo , Endogamia , Modelos Lineales , Repeticiones de Microsatélite , Modelos Genéticos , Polinización , Densidad de Población , Reproducción/genética , Semillas/genética , Análisis de Secuencia de ADN , Australia del Sur
11.
Heredity (Edinb) ; 115(2): 108-14, 2015 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-24002239

RESUMEN

Most woody plants are animal-pollinated, but the global problem of habitat fragmentation is changing the pollination dynamics. Consequently, the genetic diversity and fitness of the progeny of animal-pollinated woody plants sired in fragmented landscapes tend to decline due to shifts in plant-mating patterns (for example, reduced outcrossing rate, pollen diversity). However, the magnitude of this mating-pattern shift should theoretically be a function of pollinator mobility. We first test this hypothesis by exploring the mating patterns of three ecologically divergent eucalypts sampled across a habitat fragmentation gradient in southern Australia. We demonstrate increased selfing and decreased pollen diversity with increased fragmentation for two small-insect-pollinated eucalypts, but no such relationship for the mobile-bird-pollinated eucalypt. In a meta-analysis, we then show that fragmentation generally does increase selfing rates and decrease pollen diversity, and that more mobile pollinators tended to dampen these mating-pattern shifts. Together, our findings support the premise that variation in pollinator form contributes to the diversity of mating-pattern responses to habitat fragmentation.


Asunto(s)
Eucalyptus/genética , Bosques , Variación Genética , Genética de Población , Polinización , Animales , Aves , Genotipo , Endogamia , Insectos , Densidad de Población , Reproducción/genética , Australia del Sur
12.
Phys Rev Lett ; 113(21): 217206, 2014 Nov 21.
Artículo en Inglés | MEDLINE | ID: mdl-25479521

RESUMEN

We obtain a fundamental instability of the magnetization-switching fronts in superparamagnetic and ferromagnetic materials such as crystals of nanomagnets, ferromagnetic nanowires, and systems of quantum dots with large spin. We develop the instability theory for both linear and nonlinear stages. By using numerical simulations we investigate the instability properties focusing on spin avalanches in crystals of nanomagnets. The instability distorts spontaneously the fronts and leads to a complex multidimensional front dynamics. We show that the instability has a universal physical nature, with a deep relationship to a wide variety of physical systems, such as the Darrieus-Landau instability of deflagration fronts in combustion, inertial confinement fusion, and thermonuclear supernovae, and the instability of doping fronts in organic semiconductors.

13.
Phys Rev Lett ; 113(1): 014801, 2014 Jul 04.
Artículo en Inglés | MEDLINE | ID: mdl-25032929

RESUMEN

We demonstrate that charged particles in a sufficiently intense standing wave are compressed toward, and oscillate synchronously at, the antinodes of the electric field. We call this unusual behavior anomalous radiative trapping (ART). We show using dipole pulses, which offer a path to increased laser intensity, that ART opens up new possibilities for the generation of radiation and particle beams, both of which are high energy, directed, and collimated. ART also provides a mechanism for particle control in high-intensity quantum-electrodynamics experiments.

14.
Phys Rev Lett ; 111(6): 060404, 2013 Aug 09.
Artículo en Inglés | MEDLINE | ID: mdl-23971542

RESUMEN

We study nonperturbative pair production in intense, focused laser fields called e-dipole pulses. We address the conditions required, such as the quality of the vacuum, for reaching high intensities without initiating beam-depleting cascades, the number of pairs which can be created, and experimental detection of the created pairs. We find that e-dipole pulses offer an optimal method of investigating nonperturbative QED.

15.
Artículo en Inglés | MEDLINE | ID: mdl-24483575

RESUMEN

Recently, there has been a surge of interest in nonequilibrium collective quantum models, where particle dispersion and spin are examples of effects taken into account. Here, we derive a kinetic plasma model containing fermion exchange effects. Exchange interactions are of great importance in many systems and have no classical analogy. Our model therefore constitutes a possible probe of collective quantum phenomena in other regimes. As an example, we consider the influence of the exchange effect on low-frequency dynamics, in particular ion-acoustic waves. Comparisons to related computational techniques are given and the differences are highlighted. Furthermore, we discuss the applicability of our model, its limitations, and possible extensions.

16.
Phys Rev Lett ; 107(20): 207208, 2011 Nov 11.
Artículo en Inglés | MEDLINE | ID: mdl-22181769

RESUMEN

Recent experiments [W. Decelle et al., Phys. Rev. Lett. 102, 027203 (2009)] have discovered ultrafast propagation of spin avalanches in crystals of nanomagnets, which is 3 orders of magnitude faster than the traditionally studied magnetic deflagration. The new regime has been hypothetically identified as magnetic detonation. Here we demonstrate unequivocally the possibility of magnetic detonation in the crystals, as a front consisting of a leading shock and a zone of Zeeman energy release. We study the key features of the process and find that the magnetic detonation speed only slightly exceeds the sound speed in agreement with the experimental observations. For combustion science, our results provide a unique physical example of extremely weak detonation.

17.
Phys Rev E Stat Nonlin Soft Matter Phys ; 84(4 Pt 2): 046403, 2011 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-22181279

RESUMEN

The generation of ultrastrong attosecond pulses through laser-plasma interactions offers the opportunity to surpass the intensity of any known laboratory radiation source, giving rise to new experimental possibilities, such as quantum electrodynamical tests and matter probing at extremely short scales. Here we demonstrate that a laser irradiated plasma surface can act as an efficient converter from the femto- to the attosecond range, giving a dramatic rise in pulse intensity. Although seemingly similar schemes have been described in the literature, the present setup differs significantly from the previous attempts. We present a model describing the nonlinear process of relativistic laser-plasma interaction. This model, which is applicable to a multitude of phenomena, is shown to be in excellent agreement with particle-in-cell simulations. The model makes it possible to determine a parameter region where the energy conversion from the femto- to the attosecond regime is maximal. Based on the study we propose a concept of laser pulse interaction with a target having a groove-shaped surface, which opens up the potential to exceed an intensity level of 10(26) W/cm(2) and observe effects due to nonlinear quantum electrodynamics with upcoming laser sources.

18.
Phys Rev Lett ; 107(1): 016103, 2011 Jul 01.
Artículo en Inglés | MEDLINE | ID: mdl-21797554

RESUMEN

The dynamics of doping transformation fronts in organic semiconductor plasma is studied for application in light-emitting electrochemical cells. We show that new fundamental effects of the plasma dynamics can significantly improve the device performance. We obtain an electrodynamic instability, which distorts the doping fronts and increases the transformation rate considerably. We explain the physical mechanism of the instability, develop theory, provide experimental evidence, perform numerical simulations, and demonstrate how the instability strength may be amplified technologically. The electrodynamic plasma instability obtained also shows interesting similarity to the hydrodynamic Darrieus-Landau instability in combustion, laser ablation, and astrophysics.

19.
Eur Respir J ; 37(5): 1000-28, 2011 May.
Artículo en Inglés | MEDLINE | ID: mdl-21406515

RESUMEN

In view of the high prevalence and the relevant impairment of patients with obstructive sleep apnoea syndrome (OSAS) lots of methods are offered which promise definitive cures for or relevant improvement of OSAS. This report summarises the efficacy of alternative treatment options in OSAS. An interdisciplinary European Respiratory Society task force evaluated the scientific literature according to the standards of evidence-based medicine. Evidence supports the use of mandibular advancement devices in mild to moderate OSAS. Maxillomandibular osteotomy seems to be as efficient as continuous positive airway pressure (CPAP) in patients who refuse conservative treatment. Distraction osteogenesis is usefully applied in congenital micrognathia or midface hypoplasia. There is a trend towards improvment after weight reduction. Positional therapy is clearly inferior to CPAP and long-term compliance is poor. Drugs, nasal dilators and apnoea triggered muscle stimulation cannot be recommended as effective treatments of OSAS at the moment. Nasal surgery, radiofrequency tonsil reduction, tongue base surgery, uvulopalatal flap, laser midline glossectomy, tongue suspension and genioglossus advancement cannot be recommended as single interventions. Uvulopalatopharyngoplasty, pillar implants and hyoid suspension should only be considered in selected patients and potential benefits should be weighed against the risk of long-term side-effects. Multilevel surgery is only a salvage procedure for OSA patients.


Asunto(s)
Apnea Obstructiva del Sueño/cirugía , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Niño , Preescolar , Presión de las Vías Aéreas Positiva Contínua , Femenino , Humanos , Hueso Hioides/cirugía , Masculino , Avance Mandibular/instrumentación , Avance Mandibular/métodos , Persona de Mediana Edad , Nariz/cirugía , Osteogénesis por Distracción/instrumentación , Osteogénesis por Distracción/métodos , Hueso Paladar/cirugía , Faringe/cirugía , Terapia Recuperativa , Índice de Severidad de la Enfermedad , Lengua/cirugía , Adulto Joven
20.
Phys Rev Lett ; 105(10): 105004, 2010 Sep 03.
Artículo en Inglés | MEDLINE | ID: mdl-20867527

RESUMEN

The concept of a ponderomotive force due to the intrinsic spin of electrons is developed. An expression containing both the classical as well as the spin-induced ponderomotive force is derived. The results are used to demonstrate that an electromagnetic pulse can induce a spin-polarized plasma. Furthermore, it is shown that, for certain parameters, the nonlinear backreaction on the electromagnetic pulse from the spin magnetization current can be larger than that from the classical free current. Suitable parameter values for a direct test of this effect are presented.

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