RESUMEN
The genetic and environmental underpinnings of sleep quality have been widely investigated. However, less is known about the etiology of the different sleep quality components and their associations. Subjective sleep quality has been studied most commonly using the Pittsburgh Sleep Quality Index (PSQI). Therefore, this work aimed to study the structure of sleep quality dimensions in a population-based twin sample by examining the etiology of the associations among the PSQI components themselves and between them. The sample comprised 2129 participants from the Murcia Twin Registry. In order to study the phenotypic, genetic and environmental structure of the PSQI we used three alternative multivariate twin models including all seven sub-scales of the PSQI (subjective sleep quality, latency, duration, efficiency, disturbances, use of sleeping medication and daytime dysfunction): a multivariate model (with seven separate correlated factors), a common pathway model and an independent pathway model. The multivariate correlated factors model showed the best fit to the data. All twin models indicated significant genetic overlap among most of the PSQI components, except daytime dysfunction and use of sleep medication. Bivariate heritability explained between 25 and 50% of the covariance for most associations between dimensions. Furthermore, the common pathway model showed that around one third of the variance (0.32; CI 95% 0.18.0.43) of a latent factor common to all questionnaire dimensions is explained by genetic factors. Genetic influences on a latent factor common to all questionnaire dimensions produced the same heritability estimates as the PSQI global score. However, sleep quality dimensions showed considerable specificity regarding its genetic-environmental structure.
Asunto(s)
Trastornos del Sueño-Vigilia , Humanos , Sueño/genética , Calidad del Sueño , Trastornos del Sueño-Vigilia/genética , Encuestas y Cuestionarios , GemelosRESUMEN
BACKGROUND: Chronic low back pain (LBP), neck pain (NP), and sleep quality (SQ) are genetically influenced. All three conditions frequently co-occur and shared genetic aetiology on a pairwise base has been reported. However, to our knowledge, no study has yet investigated if these three conditions are influenced by the same genetic and environmental factors and the extent and pattern of genetic overlap between them, hence the current research. METHODS: The sample included 2134 participants. Lifetime prevalence of NP and LBP were assessed through a dichotomous self-reported question derived from the Spanish National Health Survey. SQ was measured using the Pittsburgh Sleep Quality Index Questionnaire. A common pathway model with sleep quality and back pain as latent factors was fitted. RESULTS: Our results highlight that a latent back pain factor, including both NP and LBP, is explained by both genetic (41%) and environmental (59%) factors. There are also significant unique environmental factors for NP (33%) and LBP (37%) respectively. Yet, specific genetic factors were scant (9%) for NP and negligible for LBP (0%). Genetic and environmental factors affecting SQ only contribute with 3% and 5% of the variance, respectively, to the common latent back pain variable. CONCLUSIONS: NP and LBP share most of their genetic variance, while environmental effects show greater specificity for each of the back pain locations. Associations with SQ were of a limited magnitude. SIGNIFICANCE: Our results confirm a significant association between both chronic NP and LBP and sleep quality. Such relationship comprises both genetic and environmental factors, with a greater relative weight of the latter. A large part of the individual variance for chronic LBP and chronic NP can be accounted for by a latent common factor of 'back pain'. Genetic influences for LBP and NP were mainly shared. However, environmental influences were common for both problems and specific for each of them in similar magnitudes.
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Dolor Crónico , Dolor de la Región Lumbar , Dolor Crónico/complicaciones , Dolor Crónico/epidemiología , Dolor Crónico/genética , Encuestas Epidemiológicas , Humanos , Dolor de la Región Lumbar/epidemiología , Dolor de la Región Lumbar/genética , Dolor de Cuello/epidemiología , Dolor de Cuello/genética , Calidad del SueñoRESUMEN
The aim of this research was to study the effect of a cue signalling the upcoming of a phobic picture on the electrocortical activity provoked by the disorder-relevant stimulus in in blood-injection-injury (BII) phobia and snake phobia. A sample of 13 BII phobia participants, 12 snake phobia individuals and 14 non-phobic controls underwent an S1-S2 task, where S1 was a word that described the content of a subsequent picture (blood-related, snake and neutral) that appeared 2 seconds later (S2). We obtained the P200 and P300 ERP amplitudes provoked by the pictures. Our results reveal that P200 did not differentiate between picture contents in BII phobia while, in contrast, snake and blood-related pictures provoked the largest responses in snake phobia participants. Both blood-related and snake pictures provoked greater P300 amplitudes than neutral pictures in all the groups. Threat cues reduced the electrocortical reaction of the BII phobia participants, possibly by the elicitation of anticipatory or regulatory responses. These results are indicative of a low automatic, exogenous attention towards the feared stimuli in BII phobia, as revealed by P200, probably related to a lack of attentional bias to the phobic object.(AU)
El objetivo de esta investigación fue estudiar el efecto de una señal que indica la aparición de una imagen fóbica sobre la actividad electrocortical provocada por el estímulo fóbico en personas con fobia a la sangre, inyecciones y heridas (SIH) y en fóbicos a las serpientes. Una muestra de 13 participantes con fobia SIH, 12 con fobia a las serpientes y 14 controles no fóbicos se sometieron a una tarea S1-S2, donde S1 era una palabra que describía el contenido de una imagen posterior (relacionada con sangre, serpientes o neutra) que aparecía 2 segundos después (S2). Obtuvimos las amplitudes de los potenciales evocados P200 y P300 provocados por las imágenes. Nuestros resultados revelaronn que P200 no diferenciaba entre el contenido de las imágenes en la fobia SIH mientras que, por el contrario, las imágenes relacionadas con serpientes y con sangre provocaron las mayores respuestas en los participantes con fobia a las serpientes. Tanto las imágenes relacionadas con sangre como las relacionadas con serpientes provocaron amplitudes de P300 mayores que las imágenes neutras en todos los grupos. Las señales de amenaza redujeron la reacción electrocortical de los fóbicos SIH, posiblemente porque desencadenaron respuestas anticipatorias o reguladoras. Estos resultados indican una baja atención exógena hacia los estímulos temidos en la fobia SIH, como lo revela P200, probablemente relacionada con una pérdida del sesgo atencional hacia su objeto fóbico.(AU)
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Humanos , Masculino , Femenino , Sesgo Atencional , Trastornos Fóbicos , Serpientes , Inyecciones , Heridas y Lesiones , Potenciales EvocadosRESUMEN
This study explored the effect of the perceived social content of affective pictures on the subjective evaluation of affective valence and arousal. For this purpose, we established three categories of social content (pictures without people, with one person and with two or more people). A sample of 161 subjects rated 200 pictures varying in affective valence (unpleasant, neutral, and pleasant), arousal and social content. Results of two-factor analysis of variance, F(4, 157) = 71.7, p < .001, ηp2 = .31, showed that perceived social content influenced the ratings of affective valence, specially for unpleasant pictures, with the greatest social content (two or more people) leading subjects to rate unpleasant pictures with the lowest ratings (all pairwise comparisons' p < .001). Regarding arousal, F(4, 157) = 64.0, p < .001, ηp2 = .29), the higher the social content, the higher the arousal ratings, but only for pleasant (all pairwise comparisons' p < .007) and unpleasant (all pairwise comparisons' p < .001) pictures. Overall, this study demonstrated an effect of the perceived social content on the subjective evaluation of affective valence and arousal of emotional stimuli.
Asunto(s)
Afecto , Nivel de Alerta , Emociones , Individualidad , Reconocimiento Visual de Modelos , Medio Social , Adolescente , Adulto , Femenino , Humanos , Masculino , Adulto JovenRESUMEN
This study explored the effect of the perceived social content of affective pictures on the subjective evaluation of affective valence and arousal. For this purpose, we established three categories of social content (pictures without people, with one person and with two or more people). A sample of 161 subjects rated 200 pictures varying in affective valence (unpleasant, neutral, and pleasant), arousal and social content. Results of two-factor analysis of variance, F(4, 157) = 71.7, p < .001, ηp2 = .31, showed that perceived social content influenced the ratings of affective valence, specially for unpleasant pictures, with the greatest social content (two or more people) leading subjects to rate unpleasant pictures with the lowest ratings (all pairwise comparisons' p < .001). Regarding arousal, F(4, 157) = 64.0, p < .001, ηp2 = .29), the higher the social content, the higher the arousal ratings, but only for pleasant (all pairwise comparisons' p < .007) and unpleasant (all pairwise comparisons' p < .001) pictures. Overall, this study demonstrated an effect of the perceived social content on the subjective evaluation of affective valence and arousal of emotional stimuli
No disponible
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Humanos , Masculino , Femenino , Adolescente , Adulto Joven , Adulto , Percepción Visual , Emociones/clasificación , Afecto , Medio Social , Factores Sociológicos , Nivel de Alerta , 34667 , Estudiantes/psicología , Psicología Experimental/métodosRESUMEN
Objective: To study the time course of the electrocortical activity evoked by gains and losses in the Iowa Gambling Task (IGT), the brain sources of this electrical activity, and its association with behavioral parameters of task performance in order to achieve a better knowledge of decision-making processes. Method: Event-related potentials (ERPs) were obtained from a 64-channel EEG in 25 participants when performing the IGT. Brain source localization analyses of the ERP components were also assessed. Results: ERP amplitudes were sensitive to gains and losses. An early fronto-central negativity was elicited when feedback was provided for both gains and losses, and correlated with the number of gains at FCz and with the number of both gains and losses at Cz. The P200 component had larger amplitudes to losses and correlated positively with the number of losses. Feedback related negativity (FRN) was higher at frontal, temporal and occipital electrodes in trials with monetary losses. In addition, trials with monetary losses elicited larger P300 magnitudes than trials with monetary gains at all electrode localizations. Conclusions: All ERP components (except P300) were related to participants' performance in the IGT. Amplitudes of P200 and P300 were associated with the conscious recognition of the error during the decision-making. Performance data and source analysis underline the importance of the medial prefrontal cortex when processing feedback about monetary losses in the IGT.
RESUMEN
The Murcia Twin Registry (MTR) is the only population-based registry in Spain. Created in 2006, the registry has been growing more than a decade to become one of the references for twin research in the Mediterranean region. The MTR database currently comprises 3545 adult participants born between 1940 and 1977. It also holds a recently launched satellite registry of university students (N = 204). Along five waves of data collection, the registry has gathered questionnaire and anthropometric data, as well as biological samples. The MTR keeps its main research focus on health and health-related behaviors from a public health perspective. This includes lifestyle, health promotion, quality of life or environmental conditions. Future short-term development points to the expansion of the biobank and the continuation of the collection of longitudinal data.
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Investigación Biomédica , Enfermedades en Gemelos/epidemiología , Conductas Relacionadas con la Salud , Calidad de Vida , Sistema de Registros/estadística & datos numéricos , Gemelos Dicigóticos/genética , Gemelos Monocigóticos/genética , Adulto , Enfermedades en Gemelos/genética , Enfermedades en Gemelos/psicología , Femenino , Estudios de Seguimiento , Promoción de la Salud , Humanos , Estilo de Vida , Estudios Longitudinales , Masculino , España/epidemiología , Encuestas y CuestionariosRESUMEN
The complex sensory input and motor reflexes that keep body posture and head position aligned are influenced by emotional reactions evoked by visual or auditory stimulation. Several theoretical approaches have emphasized the relevance of motor reactions in emotional response. Emotions are considered as a tendency or predisposition to act that depends on two motivational systems in the brain - the appetitive system, related to approach behaviours, and the defensive system, related to withdrawal or fight-or-flight behaviours. Few studies on emotion have been conducted employing kinematic methods, however. Motion analysis of the head may be a promising method for studying the impact of viewing affective pictures on emotional response. For this purpose, we presented unpleasant, neutral and pleasant affective pictures. Participants were instructed to view the pictures and to remain still. Two light-emitting diodes (LEDs) were attached to the foreheads of participants, and a Wii Remote controller, positioned 25 cm away, detected the position of the LEDs in the medial-lateral and anterior-posterior axes. We found more sway in response to unpleasant pictures. In addition, unpleasant pictures also provoked faster movements than both neutral and pleasant pictures. This response to unpleasant pictures, in contrast to pleasant ones, might reflect the readiness or predisposition to act. Our data also revealed that men moved faster than women, which is in accordance with previous findings related to gender differences.
RESUMEN
The social content of affective stimuli has been proposed as having an influence on cognitive processing and behaviour. This research was aimed, therefore, at studying whether automatic exogenous attention demanded by affective pictures was related to their social value. We hypothesised that affective social pictures would capture attention to a greater extent than non-social affective stimuli. For this purpose, we recorded event-related potentials in a sample of 24 participants engaged in a digit categorisation task. Distracters were affective pictures varying in social content, in addition to affective valence and arousal, which appeared in the background during the task. Our data revealed that pictures depicting high social content captured greater automatic attention than other pictures, as reflected by the greater amplitude and shorter latency of anterior P2, and anterior and posterior N2 components of the ERPs. In addition, social content also provoked greater allocation of processing resources as manifested by P3 amplitude, likely related to the high arousal they elicited. These results extend data from previous research by showing the relevance of the social value of the affective stimuli on automatic attentional processing.
Asunto(s)
Afecto/fisiología , Atención/fisiología , Potenciales Evocados/fisiología , Conducta Social , Adolescente , Adulto , Nivel de Alerta , Electroencefalografía/métodos , Femenino , Humanos , Masculino , Estimulación Luminosa/métodos , Estudiantes/psicología , Estudiantes/estadística & datos numéricos , Adulto JovenRESUMEN
OBJECTIVE: This research aimed to study the salivary flow and other autonomic reactions -heart rate (HR) and skin conductance response (SCR)- in blood-injection-injury (BII) phobia and snake phobia participants, under the assumption that exposure to blood-related pictures in BII phobia will provoke an increase in parasympathetic activity that, in turn, will lead to a greater saliva production than other affective contents. METHODS: We selected 18 BII phobia and 14 snake phobia participants along with 22 non-phobia individuals. All participants were exposed to 3 blocks of pictures (12 pictures per block) depicting either mutilations, snakes or neutral, household objects. Saliva samples were taken in the 2-min interval before and after each block. RESULTS: In comparison to other contents, blood-related pictures provoked an increase in salivary flow in BII phobia participants, as well as an increase in the number of SCRs. In the snake phobia group, snake pictures provoked HR acceleration, but the SCRs they elicited did not differ from the SCRs provoked by the blood-related pictures. CONCLUSION: BII phobia individuals react to their phobic object with a series of physiological changes resulting from a sympathetic-parasympathetic co-activation. This is in contrast with other specific phobias (e.g., small animal phobias) that usually show a sympathetically mediated, defensive reactivity when exposed to their disorder-relevant stimuli. These data support the use of therapeutic interventions in BII phobia that may differ in some respect from those used in other specific phobias.
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Sistema Nervioso Autónomo/fisiopatología , Emociones/fisiología , Trastornos Fóbicos/psicología , Serpientes/sangre , Adulto , Animales , Femenino , Humanos , Masculino , Adulto JovenRESUMEN
Study Objectives: Sleep quality is associated with health throughout the life span, which is particularly salient in middle-age and older adulthood. Sleep quality appears to be influenced by both genetic and environmental factors. However, there is still limited information about genetic influences on sleep quality in middle-aged adults, and particularly in those from certain geographical locations. We estimated the magnitude of genetic and environmental influences on sleep quality in a representative sample of middle-aged Spanish twins. Methods: The sample comprised 2150 individuals born between 1939 and 1966, who participate in the Murcia Twin Registry. To estimate the heritability of sleep quality variables, we performed univariate analyses for the global score on the Pittsburgh sleep quality index and for each of its components. Results: We found moderate but significant heritability (34%) for sleep quality. The genetic variance of the components of the Pittsburgh index ranged from 30 to 45 per cent, except for sleep efficiency for which no genetic influence could be detected. In summary, there was a moderate genetic influence on most dimensions of sleep quality in a sample of adult male and female twins. Shared environment influences were not found. Conclusions: This study adds new information regarding the underlying determinants of sleep quality by providing heritability estimates in a middle-aged population-based representative sample from a geographical location that has not been included in studies of this type previously. This could provide a reference point for future research regarding sleep research in middle-age.
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Interacción Gen-Ambiente , Sueño/genética , Gemelos Dicigóticos/genética , Gemelos Monocigóticos/genética , Adulto , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Sistema de Registros , Trastornos del Sueño-Vigilia/diagnóstico , Trastornos del Sueño-Vigilia/epidemiología , Trastornos del Sueño-Vigilia/genética , España/epidemiologíaRESUMEN
Los diseños genéticamente informativos, y en particular los estudios de gemelos, constituyen la metodología más utilizada para analizar la contribución relativa de los factores genéticos y ambientales a la variabilidad interindividual. Básicamente, consisten en comparar el grado de similitud, con respecto a una característica o rasgo determinado, entre gemelos monocigóticos y dicigóticos. Además de la clásica estimación de heredabilidad, este tipo de registros permite una amplia variedad de análisis únicos por las características de la muestra. El Registro de Gemelos de Murcia es un registro de base poblacional centrado en el análisis de conductas relacionadas con la salud. Las prevalencias de problemas de salud observadas son comparables a las de otras muestras de referencia de ámbito regional y estatal, lo que avala su representatividad. En conjunto, sus características facilitan el desarrollo de diversas modalidades de investigación, además de diseños genéticamente informativos y la colaboración con distintas iniciativas y consorcios (AU)
Genetically informative designs and, in particular, twin studies, are the most widely used methodology to analyse the relative contribution of genetic and environmental factors to inter-individual variability. These studies basically compare the degree of phenotypical similarity between monozygotic and dizygotic twin pairs. In addition to the traditional estimate of heritability, this kind of registry enables a wide variety of analyses which are unique due to the characteristics of the sample. The Murcia Twin Registry is population-based and focused on the analysis of health-related behaviour. The observed prevalence of health problems is comparable to that of other regional and national reference samples, which guarantees its representativeness. Overall, the characteristics of the Registry facilitate developing various types of research as well as genetically informative designs, and collaboration with different initiatives and consortia (AU)
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Humanos , Gemelos/genética , Estudios en Gemelos como Asunto/métodos , Registros/normas , Sistema de Registros/ética , Sistema de Registros/normas , Estudios en Gemelos como Asunto/ética , Genética Médica/métodos , Genética Conductual/ética , Genética Conductual/métodosRESUMEN
Genetically informative designs and, in particular, twin studies, are the most widely used methodology to analyse the relative contribution of genetic and environmental factors to inter-individual variability. These studies basically compare the degree of phenotypical similarity between monozygotic and dizygotic twin pairs. In addition to the traditional estimate of heritability, this kind of registry enables a wide variety of analyses which are unique due to the characteristics of the sample. The Murcia Twin Registry is population-based and focused on the analysis of health-related behaviour. The observed prevalence of health problems is comparable to that of other regional and national reference samples, which guarantees its representativeness. Overall, the characteristics of the Registry facilitate developing various types of research as well as genetically informative designs, and collaboration with different initiatives and consortia.
Asunto(s)
Interacción Gen-Ambiente , Conductas Relacionadas con la Salud , Sistema de Registros , Gemelos/estadística & datos numéricos , Enfermedades en Gemelos/epidemiología , Femenino , Genética Conductual , Genética Médica , Humanos , Individualidad , Masculino , Prevalencia , Proyectos de Investigación , España , Gemelos/psicologíaRESUMEN
Functional infrared thermal imaging (fITI) is considered a promising method to measure emotional autonomic responses through facial cutaneous thermal variations. However, the facial thermal response to emotions still needs to be investigated within the framework of the dimensional approach to emotions. The main aim of this study was to assess how the facial thermal variations index the emotional arousal and valence dimensions of visual stimuli. Twenty-four participants were presented with three groups of standardized emotional pictures (unpleasant, neutral and pleasant) from the International Affective Picture System. Facial temperature was recorded at the nose tip, an important region of interest for facial thermal variations, and compared to electrodermal responses, a robust index of emotional arousal. Both types of responses were also compared to subjective ratings of pictures. An emotional arousal effect was found on the amplitude and latency of thermal responses and on the amplitude and frequency of electrodermal responses. The participants showed greater thermal and dermal responses to emotional than to neutral pictures with no difference between pleasant and unpleasant ones. Thermal responses correlated and the dermal ones tended to correlate with subjective ratings. Finally, in the emotional conditions compared to the neutral one, the frequency of simultaneous thermal and dermal responses increased while both thermal or dermal isolated responses decreased. Overall, this study brings convergent arguments to consider fITI as a promising method reflecting the arousal dimension of emotional stimulation and, consequently, as a credible alternative to the classical recording of electrodermal activity. The present research provides an original way to unveil autonomic implication in emotional processes and opens new perspectives to measure them in touchless conditions.
Asunto(s)
Nivel de Alerta/fisiología , Emociones/fisiología , Cara/fisiología , Imagenología Tridimensional , Temperatura Cutánea/fisiología , Adulto , Femenino , Humanos , MasculinoRESUMEN
Objective: Sleep quality has a significant impact on health and quality of life and is affected, among other factors, by age and sex. However, the prevalence of problems in this area in the general population is not well known. Therefore, our objective was to study the prevalence and main characteristics of sleep quality in an adult population sample. Methods: 2,144 subjects aged between 43 and 71 years belonging to the Murcia (Spain) Twin Registry. Sleep quality was measured by self-report through the Pittsburgh Sleep Quality Index (PSQI). Logistic regression models were used to analyse the results. Results: The prevalence of poor sleep quality stands at 38.2%. Univariate logistic regression analyses showed that women were almost twice as likely as men (OR: 1.88; 95% confidence interval [95%CI]: 1.54 to 2.28) to have poor quality of sleep. Age was directly and significantly associated with a low quality of sleep (OR: 1.05; 95%CI: 1.03 to 1.06). Conclusions: The prevalence of poor sleep quality is high among adults, especially women. There is a direct relationship between age and deterioration in the quality of sleep. This relationship also appears to be more consistent in women (AU)
Objetivo: La calidad del sueño tiene una incidencia notable en la salud y en la calidad de vida, y a su vez se ve afectada, entre otros factores, por la edad y el sexo. Sin embargo, la prevalencia de problemas en este ámbito en la población general no es bien conocida. Por ello, nuestro objetivo fue estudiar la prevalencia y las características de la calidad del sueño en una muestra de población adulta. Métodos: 2144 personas de edades comprendidas entre 43 y 71 años pertenecientes al Registro de Gemelos de Murcia. La calidad del sueño se determinó por autoinforme mediante el índice de calidad del sueño de Pittsburgh. Se utilizaron modelos de regresión logística para el análisis de los resultados. Resultados: La prevalencia de una pobre calidad del sueño se sitúa en el 38,2%. Los análisis de regresión logística univariados mostraron que las mujeres prácticamente doblaban (odds ratio [OR]: 1,88; intervalo de confianza del 95% [IC95%]: 1,54-2,28) la probabilidad de tener una pobre calidad del sueño con respecto a los hombres. La edad se asocia de manera directa y significativa con una baja calidad del sueño (OR: 1,05; IC95%: 1,03-1,06). Conclusiones: La prevalencia de una pobre calidad del sueño es alta en la población adulta, en especial en las mujeres. Existe una relación directa entre la edad y el deterioro de la calidad del sueño. Esta relación también parece ser más consistente en las mujeres (AU)
Asunto(s)
Humanos , Adulto , Trastornos del Sueño-Vigilia/epidemiología , Salud Mental/clasificación , Distribución por Edad y Sexo , Encuestas y Cuestionarios , MenopausiaRESUMEN
There is a consistent relationship between body mass index and sleep quality. However, the directionality and possible confounding factors of this relationship are unclear. Our aim is to confirm the association between sleep quality and body mass index, independent of possible genetic confounding, as well as to provide some indirect inferences about the directionality of this association. The co-twin study design was used to analyse the body mass index-sleep relationship in a sample of 2150 twins. We selected two parallel sub-samples of twins discordant for body mass index (n = 430 pairs), or discordant for sleep quality (n = 316 pairs). Sleep quality and body mass index showed an inverse relationship (b = 0.056, P = 0.032) in the global sample. When twins discordant for body mass index were selected, this association maintained a similar effect size and statistical significance, at all levels of the case-control analysis (all discordant pairs b = 0.173, P < 0.001; dizygotic twins b = 0.174, P = 0.002; monozygotic twins b = 0.173, P = 0.050). Nevertheless, when twin pairs were selected on the basis of their discordance for sleep quality, the association between body mass index and sleep quality appeared weaker and lost significance (b = 0.021, P = 0.508). The analyses including only dizygotic (b = 0.028, P = 0.526) or monozygotic (b = 0.001, P = 0.984) pairs produced similar non-significant results. Our results confirm the relationship between sleep quality and body mass index, even after applying high levels of control, including genetic factors. Moreover, this study suggests a possible directionality of this relationship, such that sleep quality would strongly affect body mass index, while the opposite would be less robust and consistent in non-clinical samples.
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Índice de Masa Corporal , Sueño/fisiología , Gemelos , Adulto , Anciano , Estudios de Casos y Controles , Femenino , Humanos , Masculino , Persona de Mediana Edad , Sueño/genética , Gemelos/genética , Gemelos Dicigóticos/genética , Gemelos Monocigóticos/genéticaRESUMEN
OBJECTIVE: Sleep quality has a significant impact on health and quality of life and is affected, among other factors, by age and sex. However, the prevalence of problems in this area in the general population is not well known. Therefore, our objective was to study the prevalence and main characteristics of sleep quality in an adult population sample. METHODS: 2,144 subjects aged between 43 and 71 years belonging to the Murcia (Spain) Twin Registry. Sleep quality was measured by self-report through the Pittsburgh Sleep Quality Index (PSQI). Logistic regression models were used to analyse the results. RESULTS: The prevalence of poor sleep quality stands at 38.2%. Univariate logistic regression analyses showed that women were almost twice as likely as men (OR: 1.88; 95% confidence interval [95%CI]: 1.54 to 2.28) to have poor quality of sleep. Age was directly and significantly associated with a low quality of sleep (OR: 1.05; 95%CI: 1.03 to 1.06). CONCLUSIONS: The prevalence of poor sleep quality is high among adults, especially women. There is a direct relationship between age and deterioration in the quality of sleep. This relationship also appears to be more consistent in women.
Asunto(s)
Trastornos del Inicio y del Mantenimiento del Sueño/epidemiología , Adulto , Factores de Edad , Femenino , Humanos , Relaciones Interpersonales , Masculino , Persona de Mediana Edad , PrevalenciaRESUMEN
This research explored the underlying processes mediating risky decisions for individuals with Borderline Personality Disorder (BPD). We tested whether BPD patients were more apt to take risks compared to a matched comparison group. We used two controlled tasks designed to assess risky decision-making, both to achieve gains and to avoid losses. Overall, BPD patients showed increased risk-taking compared to the comparison group (p = .011, η2 = .224), and were especially likely to be risk-seeking when the decision was framed as a potential loss (p < .0001, d = 1.77). When the outcome involved pure losses, BPD patients were insensitive to the relative expected value between choice options resulting in suboptimal decision making (p = .004, d = 1.24), but did not differ from the comparison group when taking risks to achieve gains (p = .603, d = 0.21). We discuss these results in the context of behavioral and neuropsychiatric research suggesting abnormalities BPD patients ability to effectively regulate affect (AU)
No disponible
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Humanos , Masculino , Femenino , Toma de Decisiones en la Organización , Trastorno de Personalidad Limítrofe/psicología , Trastornos de la Personalidad/psicología , Neuropsicología/métodos , Neuropsicología/tendencias , Neuropsiquiatría/métodos , Neuropsiquiatría/normas , Neuropsiquiatría/tendencias , Análisis de Datos/métodos , Análisis de VarianzaRESUMEN
This research explored the underlying processes mediating risky decisions for individuals with Borderline Personality Disorder (BPD). We tested whether BPD patients were more apt to take risks compared to a matched comparison group. We used two controlled tasks designed to assess risky decision-making, both to achieve gains and to avoid losses. Overall, BPD patients showed increased risk-taking compared to the comparison group (p = .011, η2 = .224), and were especially likely to be risk-seeking when the decision was framed as a potential loss (p < .0001, d = 1.77). When the outcome involved pure losses, BPD patients were insensitive to the relative expected value between choice options resulting in suboptimal decision making (p = .004, d = 1.24), but did not differ from the comparison group when taking risks to achieve gains (p = .603, d = 0.21). We discuss these results in the context of behavioral and neuropsychiatric research suggesting abnormalities BPD patients' ability to effectively regulate affect.
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Trastorno de Personalidad Limítrofe/fisiopatología , Toma de Decisiones/fisiología , Asunción de Riesgos , Adolescente , Adulto , Femenino , Humanos , Masculino , Recompensa , Adulto JovenRESUMEN
We studied the changes in salivary alpha-amylase (sAA) and other psychophysiological indices (heart rate, skin conductance, and corrugator supercilii activity) elicited by sustained exposure to affective pictures. Thirty-nine subjects viewed five blocks of pictures depicting mutilations, human attack, neutral scenes, sport/adventure, and erotica. Each block comprised 12 pictures of the same content. Saliva samples were collected before and after each block of pictures. The results showed that mutilation pictures promoted the greatest increase in sAA activity and output, as well as greater corrugator supercilii activity than pleasant pictures. Skin conductance response did not differ among high arousal picture contents. Changes in sAA varied with the affective valence but not with the arousal ratings of the pictures. Our results point to sAA as an index directly related to the unpleasantness elicited by sustained exposure to affective stimuli.