RESUMEN
A 29-year-old kidney transplant recipient returning from Mali was diagnosed with Rift Valley fever (RVF) in France in autumn 2015. The patient was immunosuppressed due to his renal transplant. IgM and IgG specific to RVF virus (RVFV) were detected in cerebrospinal fluid and blood up to two months after symptom onset, whereas in urine, RVFV genomic RNA was detected by RT-PCR up to three months, and in semen up to four months post symptom onset.
Asunto(s)
Trasplante de Riñón/efectos adversos , Fiebre del Valle del Rift/diagnóstico , Fiebre del Valle del Rift/microbiología , Virus de la Fiebre del Valle del Rift/aislamiento & purificación , Análisis de Semen/métodos , Semen/virología , Adulto , Francia , Humanos , Huésped Inmunocomprometido/inmunología , Masculino , ARN Viral/análisis , Fiebre del Valle del Rift/etiología , Virus de la Fiebre del Valle del Rift/genética , Estaciones del Año , ViajeRESUMEN
Infections in the transplant patient are common. There are infections related to the host (recipient), those related to the graft and the related donor. Infectious risk factors depend on the history of the underlying disease of the transplanted organ, the donor, the immunosuppressive treatment. All pathogens, bacteria, viruses, fungi and parasites are possible but their frequency varies according to the transplanted organ, the selected immunosuppressive therapy and prophylaxis. Indeed, it is important to detect and treat latent infections in pro-transplant and prevent post-transplant infections by lifestyle and dietary measures, vaccinations, intraoperative antibiotic, antiviral, antifugal, antiparasitic treatments according graft and a variable length depending on the immunosuppression and donor-recipient status.
