Is the physical fitness of schoolchildren dependent on their physical activity levels and nutritional status? The experience from Serbia / ¿Depende la condición física de los escolares de sus niveles de actividad física y estado nutricional? La experiencia de Serbia

Introduction: based on the presumed relationship between physical activity and physical fitness, it seems reasonable to expect that being active would result in sufficient fitness levels. However, the relationship between physical activity and fitness is not so plausible and needs deeper exploration. Objectives: we conducted a study aimed at exploring: a) the potential variation in physical activity level by gender and school grade; and b) the effect of physical activity level, gender, and nutritional status on physical fitness test results. Methods: a total of 2795 males and 2614 females participated in the study (11-14 years). Their physical fitness was assessed by measuring anthropometric status, muscular fitness, endurance, flexibility, agility, and cardiorespiratory fitness, while their physical activity was assessed using the Physical Activity Questionnaire (PAQ-A). Results: a higher percentage of boys were highly active, while a higher percentage of girls were scarcely active (χ2 [2, n = 5017] = 151.4, p < 0.01). Decline in physical activity with age was higher in girls than in boys (χ2 [6, n = 5409] = 90.4, p < 0.01). MANOVA revealed a significant effect of gender (V = 0.009, F [6, 3669] = 5.29, p < 0.01), nutritional status (V = 0.193, F [12, 7340] = 65.16, p < 0.01) and physical activity levels (V = 0.043, F [12, 7340] = 13.60, p < 0.01) on tests outcomes. Conclusions: our study has shown that activity level in Serbian schoolchildren declines with age and is affected by nutritional status. Nutritional status represents a significant factor confounding physical fitness scores, regardless of activity levels (AU)

Introducción: basado en la presumible relación entre la actividad física y la condición física, parece razonable esperar que ser activo físicamente resulte en niveles suficientes de condición física. Sin embargo, la relación entre la actividad física y la forma física no es tan plausible y necesita una exploración más profunda. Objetivos: realizamos un estudio con el objetivo de explorar: a) la variación potencial en el nivel de actividad física en función del género y el grado escolar; y b) el efecto del nivel de actividad física, el género y el estado nutricional en el resultado de las pruebas de condición física. Métodos: un total de 2795 hombres y 2614 mujeres participaron en el estudio (11-14 años). Su condición física se evaluó midiendo el estado antropométrico, la aptitud muscular, la resistencia, la flexibilidad, la agilidad y la aptitud cardiorrespiratoria, mientras que la actividad física se evaluó mediante el Cuestionario de Actividad Física (PAQ-A). Resultados: un mayor porcentaje de niños eran muy activos, mientras que un mayor porcentaje de niñas eran poco activas (χ2 [2, n = 5017] = 151,4, p < 0,01). La disminución de la actividad física con el incremento de la edad fue mayor en las niñas que en los niños (χ2 [6, n = 5409] = 90,4, p < 0,01). El MANOVA reveló un efecto significativo del género (V = 0.009, F [6, 3669] = 5.29, p < 0.01), el estado nutricional (V = 0.193, F [12, 7340] = 65.16, p < 0.01) y los niveles de actividad física (V = 0.043, F [12, 7340] = 13.60, p < 0.01) en los resultados de las pruebas. Conclusiones: nuestro estudio ha demostrado que el nivel de actividad física en los escolares serbios disminuye con la edad y se ve afectado por el estado nutricional. El estado nutricional representa un factor significativo que confunde las puntuaciones de condición física, independientemente de los niveles de actividad (AU)

Adverse events in apheresis: An update of the WAA registry data.

Apheresis with different procedures and devices are used for a variety of indications that may have different adverse events (AEs). The aim of this study was to clarify the extent and possible reasons of various side effects based on data from a multinational registry. The WAA-apheresis registry data focus on adverse events in a total of 50846 procedures in 7142 patients (42% women). AEs were graded as mild, moderate (need for medication), severe (interruption due to the AE) or death (due to AE). More AEs occurred during the first procedures versus subsequent (8.4 and 5.5%, respectively). AEs were mild in 2.4% (due to access 54%, device 7%, hypotension 15%, tingling 8%), moderate in 3% (tingling 58%, urticaria 15%, hypotension 10%, nausea 3%), and severe in 0.4% of procedures (syncope/hypotension 32%, urticaria 17%, chills/fever 8%, arrhythmia/asystole 4.5%, nausea/vomiting 4%). Hypotension was most common if albumin was used as the replacement fluid, and urticaria when plasma was used. Arrhythmia occurred to similar extents when using plasma or albumin as replacement. In 64% of procedures with bronchospasm, plasma was part of the replacement fluid used. Severe AEs are rare. Although most reactions are mild and moderate, several side effects may be critical for the patient. We present side effects in relation to the procedures and suggest that safety is increased by regular vital sign measurements, cardiac monitoring and by having emergency equipment nearby.

Respiratory adaptations in different types of sport.

OBJECTIVE: Recent studies demonstrated that current European Respiratory Society/American Thoracic Society spirometric reference equations, used in general population, may not be applicable in population of elite athletes. Althought it is well known that physical activity may affect lung volumes, the effect of sporting activity on pulmonary function testing indices was never examined. The aim of this study was to examine the differences in functional respiratory parameters in various types of sports by measuring lung volumes and to extend the existing factors as well as sport disciplines which affect respiratory function the most. SUBJECTS AND METHODS: A total of 1639 elite male athletes, aged 18-35 years were divided in 4 groups according to the predominant characteristics of training: skill, power, mixed and endurance athletes. They performed basic anthropometric measurements and spirometry. Groups were compared, and Pearson's simple correlation was performed to test the relation between anthropometric and spirometric characteristics of athletes. RESULTS: All anthropometric characteristics significantly differed among groups and correlate with respiratory parameters. The highest correlation was found for body height and weight. CONCLUSIONS: Sports participation is associated with respiratory adaptation, and the extent of adaptation depends on type of activity. Endurance sports athletes have higher lung volumes in comparison with skill, mixed and power group of sport.

Respiratory parameters in elite athletes--does sport have an influence?

INTRODUCTION: Unlike large population studies about cardiovascular components and how they adapt to intensive physical activity, there is less research into the causes of enlargement of the respiratory system in athletes (e.g. vital capacity, maximum flow rates and pulmonary diffusion capacity). The purpose of this research was to study and compare pulmonary function in different types of sports and compare them with controls in order to find out which sports improve lung function the most. MATERIALS AND METHOD: Pulmonary functional capacities, vital capacity (VC), forced vital capacity (FVC), forced expiratory volume in one second (FEV1) and maximum voluntary ventilation (MVV) of 493 top athletes belonging to 15 different sports disciplines and of 16 sedentary individuals were studied. Pulmonary function test was performed according to ATS/ERS guidelines. RESULTS: Basketball, water polo players and rowers had statistically higher vital capacity (VC), forced vital capacity (FVC), forced expiratory volume in one second (FEV1) than the healthy sedentary control individuals. Football and volleyball players had lower VC while FVC was higher in the football group compared to controls. Peak expiratory flow was lower in boxing, kayak, rugby, handball, taekwondo and tennis. The maximum voluntary ventilation (MVV) was significantly higher in water polo players and rowers. Boxers had statistically lower MVV than the controls. Players of other sports did not differ from the control group. CONCLUSION: The study suggests that specific type of training used in basketball, water polo or rowing could have potential for improving pulmonary function and rehabilitation.

Importance of characteristics and modalities of physical activity and exercise in the management of cardiovascular health in individuals with cardiovascular risk factors: recommendations from the EACPR. Part II.

In a previous paper, as the first of a series of three on the importance of characteristics and modalities of physical activity (PA) and exercise in the management of cardiovascular health within the general population, we concluded that, in the population at large, PA and aerobic exercise capacity clearly are inversely associated with increased cardiovascular disease risk and all-cause and cardiovascular mortality and that a dose­response curve on cardiovascular outcome has been demonstrated in most studies. More and more evidence is accumulated that engaging in regular PA and exercise interventions are essential components for reducing the severity of cardiovascular risk factors, such as obesity and abdominal fat, high BP, metabolic risk factors, and systemic inflammation. However, it is less clear whether and which type of PA and exercise intervention (aerobic exercise, dynamic resistive exercise, or both) or characteristic of exercise (frequency, intensity, time or duration, and volume) would yield more benefit for each separate risk factor. The present paper, therefore, will review and make recommendations for PA and exercise training in the management of cardiovascular health in individuals with cardiovascular risk factors. The guidance offered in this series of papers is aimed at medical doctors, health practitioners, kinesiologists, physiotherapists and exercise physiologists, politicians, public health policy makers, and individual members of the public. Based on previous and the current literature overviews, recommendations from the European Association on Cardiovascular Prevention and Rehabilitation are formulated regarding type, volume, and intensity of PA and regarding appropriate risk evaluation during exercise in individuals with cardiovascular risk factors.

Dietary supplements and medications in elite sport--polypharmacy or real need?

The aim of this study was to describe qualitatively and quantitatively dietary supplements (DS) and medication use in elite athletes. Athletes (n=912; age 23.9 ± 6 years; 72% male) reported medications and DSs taken within 3 days before doping control. We analyzed data collected from 2006 to 2008, identified and classified substances. Total of 74.6% athletes reported use of at least one substance, 61.2% took DS (3.17 per user) and 40.6% took medications. Among users, 21.2% reported the use of six and more different products, and one took 17 different products at the same time. Majority of medication users took non-steroidal anti-inflammatory drugs (NSAID) (24.7%), and 22.2% used more than one NSAID. We found no gender differences in DS use (P=0.83). Individual sport athletes used more DS (P<0.01). Our study showed widespread use of DS and drugs by elite athletes. Consumption of DS with no evident performance or health benefits, demonstrated the need for specific educational programs focused on DS use. Amount, quantity and combination of the reported products raised concern about the risk of potential side effects.

Toxicity related to autologous peripheral blood haematopoietic progenitor cell infusion is associated with number of granulocytes in graft, gender and diagnosis of multiple myeloma.

BACKGROUND AND OBJECTIVES: We prospectively evaluated the infusion-related toxicity of autologous peripheral blood progenitor cells (PBPC) in 215 patients with haematologic malignancies or solid tumours. MATERIALS AND METHODS: PBPCs were collected by apheresis after mobilization with chemotherapy and/or granulocyte-colony-stimulating factor (G-CSF). The grafts were cryopreserved in 10% dimethyl sulfoxide (DMSO) and stored in liquid nitrogen. Patients were monitored for vital signs and symptoms of the toxicity during and after infusion. RESULTS: The adverse reactions were reported during 149 (56.9%) infusions. During 21.0% infusions occurred just one symptom classified as grade 1, while during 35.9% occurred multiple symptoms classified as grade 2. Logistic regression analysis showed that female gender, diagnosis of multiple myeloma and number of granulocytes infused per kg body weight were significant predictors of occurrence of adverse reactions during infusion. CONCLUSION: Our results indicate that beside the infused DMSO dose, the composition of graft as well as patient's diagnosis are also very important factors for infusion-related toxicity.

A simple and reliable step-test for indirect evaluation of aerobic capacity.

Substantial data confirm the benefits of physical activity, but it is necessary to prescribe exercise correctly in regard to aerobic capacity of each patient. When undertaking investigation of a great number of people, it is necessary to apply a simple, fast, reliable and inexpensive test. The aim of this study was to evaluate the validity of a new step-test in physically active subjects. Thirty-eight male athletes (mean age 16.6 +/- 0.3 years) and 38 nonathletes of the same age, underwent Astrand cycle-ergometer test and a new ergometric step-test. In the ergometric step-test a fixed workload (W) of 12 kJ was used, whereas the bench height (h in cm) was determined according to body mass of each subject (h = W/2.g.n) (W = workload in kJ; BM = body mass in kg; n = step rate, 25 steps + min-1). The step-test lasted 6 minutes. Values of maximal oxygen consumption (VO2 max) were determined using a nomogram, according to workload and heart rate (HR). Comparing data concerning VO2 max in Astrand and step-test, no significant differences were observed in either group: athletes (3505.6 +/- 784.7 vs. 3294.9 +/- 653.4 mL.min-1 for the step-test; p > 0.05) and in nonathletes (2563.3 +/- 469.3 vs. 2471.8 +/- 353.6 mL + min-1; p > 0.05). In our opinion our new, modified ergometric step-test is a test with high degree of validity and can be used as an easy and fast procedure instead of Astrand test which is most frequently used for indirect evaluation of aerobic capacity.