Synthesis and crystal structures of two purpurin derivatives: 1,4-dihy-droxy-2-propoxyanthra-quinone and 2-but-oxy-1,4-di-hydroxy-anthra-quinone.

The title compounds were obtained by deprotonation of 1,2,4-tri-hydroxy-anthra-quinone (purpurin) using sodium hydride followed by reaction with either 1-bromo-propane or 1-bromo-butane. 1,4-Dihy-droxy-2-propoxyanthra-quinone crystallizes as a 1:1 solvate from aceto-nitrile, C17H14O5·CH3CN. The anthra-quinone core of the mol-ecule is essentially planar and both hy-droxy groups participate in intra-molecular O-H⋯O (carbon-yl) hydrogen bonds. The propyl chain is angled slightly above the plane of the anthra-quinone moiety with a maximum deviation of 0.247 (2) Šabove the plane for the terminal carbon atom. In contrast, 2-but-oxy-1,4-di-hydroxy-anthra-quinone, C18H16O5, crystallizes from nitro-methane with two independent mol-ecules in the asymmetric unit. The anthra-quinone core of each independent mol-ecule is essentially planar and both hy-droxy groups on both mol-ecules participate in intra-molecular O-H⋯O(carbon-yl) hydrogen bonds. The butyl chain in one mol-ecule is also angled slightly above the plane of the anthra-quinone moiety, with a maximum deviation of 0.833 (5) Šabove the plane for the terminal carbon atom. In contrast, the butyl group on the second mol-ecule is twisted out of the plane of the anthra-quinone core with a torsion angle of 65.1 (3)°, resulting in a maximum deviation of 1.631 (5) Šabove the plane for the terminal carbon atom.

Role strain in occupational therapy fieldwork educators.

OBJECTIVE: The purpose of this study was to determine if occupational therapy fieldwork educators are experiencing role strain. PARTICIPANTS: Were recruited from a convenience sample of a university database of 315 fieldwork sites. METHODS: The Role Strain in Occupational Therapy Fieldwork Educators Inventory was used to gather qualitative and quantitative data about practice. RESULTS: The overall mean for role strain was 2.34/5 with a 73% return rate. The majority of participants fell into the moderate to low role strain category. Individuals with 5-10 years of practice had the greatest amount of role strain (2.43, SD 0.51, n=60). Participants working in pediatric settings had role strain in the moderate range. CONCLUSIONS: Nine items emerged with the highest amount of role strain, such as coping with job expectations and inadequate time to meet role expectations. Creation of strategies to reduce role strain should be a priority in our changing healthcare environment.