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1.
Sci Rep ; 13(1): 14919, 2023 Sep 10.
Artículo en Inglés | MEDLINE | ID: mdl-37691024

RESUMEN

We present a method of designing and fabricating 3D carbon fiber lattices. The lattice design and fabrication is based on crocheting and sewing techniques, where carbon fiber tow is woven through two parallel carbon fiber grids and reinforced with vertical carbon fiber tubes. Compression testing is then performed on three different designs, and these results are compared to other similar lattice structures, finding that the lattices perform similarly to comparable lattices. Finite element analysis is also performed to validate the experimental findings, and provides some insight into the experimental results. The process presented here allows for more design flexibility than other current methods. For example, within a single lattice, different density weave patterns can be used to address specific load requirements. Though fabricated manually here, this process can also be automated for large scale production. With this design flexibility, simplified fabrication, and high strength, the lattices proposed here offer an advantage as compared to similar existing structures.

2.
Sci Robot ; 3(14)2018 01 17.
Artículo en Inglés | MEDLINE | ID: mdl-33141699

RESUMEN

Delta robots have been widely used in industrial contexts for pick-and-place applications because of their high precision and speed. These qualities are also desirable at the millimeter scale for applications such as vibration cancellation in microsurgery and microassembly or micromanipulation. Developing a millimeter-scale Delta robot that maintains the characteristic input-output behavior and operates with high speed and precision requires overcoming manufacturing and actuation challenges. We present the design, fabrication, and characterization of an adapted Delta robot at the millimeter scale (the "milliDelta") that leverages printed circuit microelectromechanical system manufacturing techniques and is driven by three independently controlled piezoelectric bending actuators. We validated the design of the milliDelta, where two nonintersecting perpendicular revolute joints were used to replace an ideal universal joint. In addition, a transmission linkage system for actuation was introduced to the laminate structure of the milliDelta. This 15 millimeter-by-15 millimeter-by-20 millimeter robot has a total mass of 430 milligrams and a payload capacity of 1.31 grams and operates with precision down to ~5 micrometers in a 7.01-cubic-millimeter workspace. In addition, the milliDelta can follow periodic trajectories at frequencies up to 75 hertz, experiencing velocities of ~0.45 meters per second and accelerations of ~215 meters per squared second. We demonstrate its potential utility for high-bandwidth, high-precision applications that require a compact design.

3.
Lab Chip ; 17(20): 3474-3488, 2017 10 11.
Artículo en Inglés | MEDLINE | ID: mdl-28906525

RESUMEN

3D printed biomaterials with spatial and temporal functionality could enable interfacial manipulation of fluid flows and motile cells. However, such dynamic biomaterials are challenging to implement since they must be responsive to multiple, biocompatible stimuli. Here, we show stereolithographic printing of hydrogels using noncovalent (ionic) crosslinking, which enables reversible patterning with controlled degradation. We demonstrate this approach using sodium alginate, photoacid generators and various combinations of divalent cation salts, which can be used to tune the hydrogel degradation kinetics, pattern fidelity, and mechanical properties. This approach is first utilized to template perfusable microfluidic channels within a second encapsulating hydrogel for T-junction and gradient devices. The presence and degradation of printed alginate microstructures were further verified to have minimal toxicity on epithelial cells. Degradable alginate barriers were used to direct collective cell migration from different initial geometries, revealing differences in front speed and leader cell formation. Overall, this demonstration of light-based 3D printing using non-covalent crosslinking may enable adaptive and stimuli-responsive biomaterials, which could be utilized for bio-inspired sensing, actuation, drug delivery, and tissue engineering.


Asunto(s)
Alginatos/química , Materiales Biocompatibles/química , Hidrogeles/química , Técnicas Analíticas Microfluídicas , Impresión Tridimensional , Materiales Biocompatibles/toxicidad , Línea Celular , Supervivencia Celular/efectos de los fármacos , Ácido Glucurónico/química , Ácidos Hexurónicos/química , Humanos , Ensayo de Materiales
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