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1.
J Rehabil Med ; 46(5): 520-526, 2014 06.
Artículo en Inglés | MEDLINE | ID: mdl-24941135

RESUMEN

Objectives: To explore the influence of socio-demographic and clinical oral health factors on oral health-related quality of life (OHRQoL) in patients after stroke, and to monitor OHRQoL outcomes following the provision of an in-hospital oral health intervention programme. Design: OHRQoL was measured before and after randomization and provision of oral health promotion interventions in a prospective clinical trial. Subjects: Eighty-one patients admitted to a stroke rehabilitation ward. Methods: OHRQoL was assessed using the Oral Health Impact Profile-14 (OHIP-14) and Oral Health Transition Scale upon admission and 3 weeks later following provision of an oral health promotion programme. Potential factors were examined for their association with OHRQoL outcomes. Results: Lack of a regular daily brushing habit was significantly associated with 6 of 8 transition scale items (p < 0.01) at baseline, while significant improvements in OHRQoL were observed over the course of the clinical trial for all patients as a whole (p < 0.05). Conclusion: OHRQoL is compromised following stroke and may be influenced by the lack of a regular daily brushing habit during hospitalization. The early re-establishment of an oral hygiene protocol is a priority in stroke rehabilitation wards in order to improve clinical oral health and OHRQoL.

2.
BMC Oral Health ; 14: 8, 2014 Jan 25.
Artículo en Inglés | MEDLINE | ID: mdl-24460663

RESUMEN

BACKGROUND: Chronic orofacial pain (OFP) is common in general adult populations worldwide. High levels of psychological distress and impaired coping abilities are common among Western people with chronic OFP but limited information was found in southern Chinese people. This study aimed to explore the perceptions and experiences of community dwelling elderly people with chronic OFP symptoms and their treatment seeking behaviour in Hong Kong. METHODS: An exploratory qualitative interview study was conducted. Elderly people experiencing chronic OFP symptoms were invited to take part in an individual semi-structured interview. A total of 25 semi-structured interviews were performed for 25 participants. RESULTS: Pertinent issues relating to the treatment seeking behaviour emerged from the interviews, many of which were inter-related and overlapping. They were organized into three major themes: (i) Impact of chronic OFP on daily life; (ii) Personal knowledge and feeling of chronic OFP; (iii) Management of chronic OFP. The participants were found to have the intention to seek professional treatment, but there were barriers which discouraged them continuing to seek professional treatment. They also received complementary treatment for chronic OFP, such as acupuncture, massage and "chi kung". Moreover, a wide range self-management techniques were also mentioned. On the other hand, those who did not seek professional treatment for the chronic OFP claimed that they had accepted or adapted to the pain as part of their lives. CONCLUSIONS: This qualitative study observed that elderly people affected by chronic OFP symptoms in Hong Kong sought many different ways to manage their pain including traditional and complementary approaches. The role of the dentist in dealing with chronic OFP is unclear. Multiple barriers exist to accessing care for chronic OFP. The findings may be used to inform future chronic OFP management strategies in Hong Kong.


Asunto(s)
Dolor Crónico/psicología , Dolor Facial/psicología , Aceptación de la Atención de Salud , Actividades Cotidianas , Terapia por Acupuntura , Afecto , Anciano , Anciano de 80 o más Años , Actitud Frente a la Salud , China/etnología , Dolor Crónico/terapia , Dolor Facial/terapia , Relaciones Familiares , Femenino , Conocimientos, Actitudes y Práctica en Salud , Accesibilidad a los Servicios de Salud , Hong Kong , Humanos , Vida Independiente , Intención , Relaciones Interpersonales , Masculino , Masaje , Medicina Tradicional China , Persona de Mediana Edad , Investigación Cualitativa , Autocuidado , Apoyo Social
3.
Am J Infect Control ; 41(2): 149-54, 2013 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-22818804

RESUMEN

BACKGROUND: Despite the role of the oral cavity as a reservoir of opportunistic pathogens for infection in patients following stroke, the evaluation of the effects of oral hygiene interventions has been largely neglected. METHODS: This randomized clinical trial included 102 patients undergoing hospital-based rehabilitation for stroke. Patients were randomized to one of 3 groups: oral hygiene instruction (OHI) only; OHI and 0.2% chlorhexidine mouth rinse twice daily; or OHI, 0.2% chlorhexidine mouth rinse twice daily, and assisted brushing twice weekly. Oral samples were obtained at baseline and after 3 weeks for detection of Staphylococcus aureus, aerobic and facultatively anaerobic gram-negative bacilli, and yeasts. RESULTS: Almost three-quarters (72.8%) of the patients harbored oral anaerobic gram-negative bacilli at baseline, and more than half had detectable S aureus (56.8%) and yeasts (59.3%). Percentage frequencies and viable counts of pathogens remained relatively stable during the course of the clinical trial, and no significant differences were observed among the 3 patient groups. CONCLUSIONS: In our study cohort, there was no significant difference in the effectiveness of the 3 different oral hygiene interventions on the prevalence or viable counts of oral opportunistic pathogens.


Asunto(s)
Control de Enfermedades Transmisibles/métodos , Infecciones Oportunistas/prevención & control , Higiene Bucal/métodos , Accidente Cerebrovascular/complicaciones , Antiinfecciosos Locales/administración & dosificación , Clorhexidina/administración & dosificación , Bacterias Anaerobias Gramnegativas/aislamiento & purificación , Humanos , Boca/microbiología , Staphylococcus aureus/aislamiento & purificación , Resultado del Tratamiento , Levaduras/aislamiento & purificación
4.
Arch Phys Med Rehabil ; 94(3): 435-43, 2013 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-23127306

RESUMEN

OBJECTIVE: To evaluate the effectiveness of oral health promotion interventions on clinical oral health. DESIGN: Single-blind randomized controlled trial conducted over 3 weeks of in-hospital rehabilitation. SETTING: Stroke rehabilitation ward in Hong Kong. PARTICIPANTS: Patients with stroke (N=102) admitted to the rehabilitation ward. INTERVENTIONS: Patients were randomly assigned either: (1) oral hygiene instruction, (2) oral hygiene instruction and chlorhexidine mouthrinse, or (3) oral hygiene instruction, chlorhexidine mouthrinse, and assisted brushing. MAIN OUTCOME MEASURES: Dental plaque, gingival bleeding, and oral functional status were assessed at baseline and review. Development of infectious complications were also monitored during the clinical trial. RESULTS: Poor oral hygiene and an overall neglect of oral hygiene practices were observed at baseline. Reductions in dental plaque were significantly greater in the 2 groups receiving chlorhexidine compared with the group receiving oral hygiene instruction alone (P<.001). Reductions in gingival bleeding scores were 3- to 4-fold greater in groups receiving chlorhexidine. No cases of pneumonia were observed during the course of the clinical trial. CONCLUSIONS: The oral health condition of patients may be safeguarded after acute stroke with the use of chlorhexidine mouthrinse in conjunction with a standard mechanical plaque removal tool, such as an electric toothbrush. These interventions are acceptable to the majority of patients, and their administration poses a minimal burden to rehabilitation ward staff.


Asunto(s)
Promoción de la Salud/métodos , Higiene Bucal , Rehabilitación de Accidente Cerebrovascular , Anciano , Distribución de Chi-Cuadrado , Clorhexidina/administración & dosificación , Índice de Placa Dental , Evaluación de la Discapacidad , Femenino , Hong Kong , Humanos , Modelos Lineales , Masculino , Persona de Mediana Edad , Antisépticos Bucales/administración & dosificación , Método Simple Ciego , Estadísticas no Paramétricas , Accidente Cerebrovascular/fisiopatología , Resultado del Tratamiento
5.
J Prosthet Dent ; 104(1): 1-5, 2010 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-20620364

RESUMEN

Prosthodontic rehabilitation of a surgically resected/reconstructed jaw with a conventional tissue-borne dental prosthesis is often challenging, if not impossible, because of the suboptimal conditions of the soft and hard tissue topography/architecture of the reconstructed site. Placing dental implants in grafted bone to provide appropriate support, stability, and retention for prosthodontic rehabilitation offers the potential for improved oral function. There are, however, some clinical conditions for which an implant-supported removable prosthesis may be preferred to a fixed implant prosthesis. This clinical report describes the design and fabrication of a milled bar and a tooth- and implant-supported removable dental prosthesis for oral rehabilitation of a reconstructed mandible, which considers patient factors associated with oral and financial conditions, ease of oral hygiene procedures, and long-term maintenance.


Asunto(s)
Trasplante Óseo/métodos , Pilares Dentales , Implantes Dentales , Prótesis Dental de Soporte Implantado , Diseño de Dentadura , Dentadura Parcial Removible , Mandíbula/cirugía , Procedimientos de Cirugía Plástica/métodos , Anciano , Ameloblastoma/cirugía , Retención de Dentadura/instrumentación , Humanos , Magnetismo/instrumentación , Masculino , Neoplasias Mandibulares/cirugía , Osteogénesis por Distracción/métodos , Vestibuloplastia/métodos
6.
J Orofac Pain ; 24(2): 181-8, 2010.
Artículo en Inglés | MEDLINE | ID: mdl-20401356

RESUMEN

AIMS: To investigate key factors associated with treatment-seeking for orofacial pain symptoms in community-dwelling adult Chinese people in Hong Kong. METHODS: A cross-sectional study was conducted using a Hong Kong Hospital Authority Family Medicine Clinic as the sampling frame. People aged 35 to 70 years with recent orofacial pain symptoms participated. Standard questions were asked about orofacial pain symptoms and characteristics in the previous month, Oral Health Impact Profile (OHIP-14), General Health Questionnaire (GHQ-12), Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) depression/nonspecific physical symptoms (NPS) scales, sleep and illness behavior measures, and questions on pain disability, professional treatment-seeking, pain medication usage, and dental attendance were administered prior to a standard clinical assessment. Multiple logistic regression with a forward stepwise selection method was used for data analysis. RESULTS: Two hundred people with orofacial pain symptoms participated in the definitive study. Twenty-seven percent had sought professional advice. The majority had consulted a medical practitioner (66.7%) or dentist (40.7%), 16.7% had consulted a traditional Chinese medicine (TCM) practitioner, and the majority (60%) had taken pain medication. There was no significant association between different orofacial pain diagnoses and professional treatment-seeking (P = .602). Four independent factors were significantly related to an increased likelihood of treatment-seeking (P < .05): more frequent dental attendance for check-up (odds ratio [OR] > 3), time when pain was experienced during the past month (days) (OR > 5), multiple pain symptoms (OR = 4.99), and use of TCM when ill (OR = 3.31). CONCLUSION: Professional treatment-seeking for orofacial pain was low in this ethnic group. The strongest predictor of treatment-seeking for orofacial pain was an increase in the number of days when pain was experienced during the past month. Key factors associated with treatment-seeking should be considered when formulating community health outreach programs. A further validation study with a larger sample size is recommended to confirm the present findings.


Asunto(s)
Dolor Facial/terapia , Aceptación de la Atención de Salud , Adulto , Anciano , Analgésicos/uso terapéutico , Actitud Frente a la Salud , Síndrome de Boca Ardiente/diagnóstico , Estudios Transversales , Atención Odontológica , Depresión/diagnóstico , Dolor Facial/psicología , Femenino , Estado de Salud , Hong Kong , Humanos , Conducta de Enfermedad , Masculino , Medicina Tradicional China , Persona de Mediana Edad , Salud Bucal , Calidad de Vida , Trastornos del Sueño-Vigilia/diagnóstico , Trastornos de la Articulación Temporomandibular/diagnóstico , Factores de Tiempo , Odontalgia/diagnóstico
7.
Eur J Orthod ; 31(3): 300-5, 2009 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-19193707

RESUMEN

The association between craniofacial morphology and congenitally missing teeth is at present unclear. The aims of this study were to investigate whether hypodontia is associated with changes in the sagittal skeletal profile and to identify putative relationships between the skeletal profile and the severity of hypodontia. In a cross-sectional analytical study, the craniofacial structure and profile based on two-dimensional lateral cephalograms of Southern Chinese hypodontia patients (n = 49, 24 males, 25 females, mean age 16.4 years) and a comparison group without hypodontia (n = 41, 15 males, 26 females, mean age 16.7 years) were compared. The hypodontia patients were divided into three subgroups according to the severity of hypodontia (mild: < or =5, moderate: 6-9, and severe: > or =10 congenitally missing permanent teeth). All hypodontia patients had a significantly reduced mandibular plane, ANB, and face height compared with the control group (P < 0.05). A significant increase in chin thickness was also observed in the hypodontia patients (P < 0.05). As the severity of hypodontia increased from moderate to severe, a tendency to develop a retrognathic maxilla and a Class III skeletal relationship was noted in addition to the above features, making the already thick chin even more prominent. Statistically significant correlations (Pearson's correlation coefficient) were found between the number of missing teeth and SNA, NAFH, and ANB angles, the mandibular plane, chin thickness, and face height. In Southern Chinese subjects, hypodontia was associated with a shorter face, a flatter mandibular plane, a more pronounced chin, and a Class III skeletal profile. In severe hypodontia subjects, the maxilla was more retrognathic with a greater predilection to a Class III skeletal relationship.


Asunto(s)
Anodoncia/patología , Cara , Huesos Faciales/patología , Cráneo/patología , Adolescente , Adulto , Anodoncia/clasificación , Cefalometría/métodos , Niño , Mentón/patología , China , Estudios Transversales , Oído Externo/patología , Femenino , Humanos , Procesamiento de Imagen Asistido por Computador/métodos , Masculino , Maloclusión de Angle Clase III/patología , Mandíbula/patología , Maxilar/patología , Desarrollo Maxilofacial , Hueso Nasal/patología , Órbita/patología , Silla Turca/patología , Dimensión Vertical , Adulto Joven
8.
J Prosthet Dent ; 101(1): 66-72, 2009 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-19105993

RESUMEN

STATEMENT OF PROBLEM: Early loss of magnetic keepers in cast gold posts is seen in clinical practice. PURPOSE: The purpose of this vitro study was to investigate the effect of burn-out temperature on the retention of magnetic keepers in cast gold alloy and on the thickness of the oxide layer at the keeper-alloy interface. MATERIAL AND METHODS: One hundred and five keepers (Magfit EX) were cast with gold alloy (Protor 3) at 3 different burn-out temperatures: 500 degrees C, 600 degrees C, or 700 degrees C (n=35). To test for retention of keepers, 60 specimens (n=20) were tested to failure in tension mode in a universal testing machine (UTM); 45 specimens (n=15) were sectioned, and the interface was evaluated under a scanning electron microscope (SEM). Tensile force data were analyzed with 1-way ANOVA, and SEM data were analyzed with 1-way repeated measures ANOVA. Bonferroni multiple comparisons were performed for post hoc analysis (alpha=.05). RESULTS: Retention of the keepers was significantly higher at lower burn-out temperatures (P<.001). The retention of the keepers became unpredictable and immediate failures were observed at a burn-out temperature of 700 degrees C. Oxide formation at the keeper-alloy interface was significantly less at lower burn-out temperatures (P<.001). CONCLUSIONS: A burn-out temperature of 500 degrees C for casting the Magfit EX keeper with type IV high-strength gold alloy is recommended.


Asunto(s)
Técnica de Colado Dental , Fracaso de la Restauración Dental , Retención de Dentadura/instrumentación , Aleaciones de Oro , Magnetismo/instrumentación , Técnica de Perno Muñón , Sulfato de Calcio , Aleaciones Dentales , Revestimiento para Colado Dental , Análisis del Estrés Dental , Prótesis de Recubrimiento , Aleaciones de Oro/química , Calor , Óxidos , Acero Inoxidable , Resistencia a la Tracción
9.
J Orofac Pain ; 22(4): 307-16, 2008.
Artículo en Inglés | MEDLINE | ID: mdl-19090403

RESUMEN

This tribute article to Professor Alan G. Hannam is based on 7 presentations for him at the July 1, 2008 symposium honoring 3 "giants" in orofacial neuroscience: Professors B. J. Sessle, J. P. Lund, and A. G. Hannam. This tribute to Hannam's outstanding career draws examples from his 40-year academic career and spans topics from human evolution to complex modeling of the craniomandibular system. The first presentation by W. Hylander provides a plausible answer to the functional and evolutionary significance of canine reduction in hominins. The second presentation, by A. McMillan, describes research activities in the field of healthy aging, including findings that intensity-modulated radiotherapy improves the health condition and quality of life of people with nasopharyngeal carcinoma in comparison to conventional radiotherapy. The developments in dental imaging are summarized in the third paper by E. Lam, and an overview of the bite force magnitude and direction while clenching is described in the fourth paper by M. Watanabe. The last 3 contributions by G. Langenbach, I. Staveness, and C. Peck deal with the topic of bone remodeling as well as masticatory system modeling, which was Hannam's main research interest in recent years. These contributions show the considerable advancements that have been made in the last decade under Hannam's drive, in particular the development of an interactive model comprising, in addition to the masticatory system, also the upper airways. The final section of the article includes a final commentary from Professor Hannam.


Asunto(s)
Músculos Faciales/fisiología , Fenómenos Fisiológicos del Sistema Nervioso , Animales , Evolución Biológica , Fuerza de la Mordida , Remodelación Ósea , Humanos , Imagenología Tridimensional , Maxilares/fisiología , Masticación , Músculos Masticadores/fisiología , Modelos Biológicos , Movimiento , Neoplasias Nasofaríngeas/radioterapia , Prostodoncia
10.
J Orofac Pain ; 22(4): 323-30, 2008.
Artículo en Inglés | MEDLINE | ID: mdl-19090405

RESUMEN

AIMS: To investigate chronic orofacial pain experience, psychosocial impact, and help-seeking response in adult Chinese people in Hong Kong. METHODS: A cross-sectional population-based telephone interview survey identified 1352 randomly selected people aged > or =18 years. Standard questions were asked about current or episodic and prior (> or = 6 months) experience of 7 orofacial pain symptoms. Pain intensity and psychosocial impact were assessed through the Graded Chronic Pain Scale, and the help-seeking response was assessed using the 4-item Level of Expressed Need (LEN) measure. RESULTS: Current or episodic symptoms of orofacial pain were reported by 57.0% of respondents, and 13.2% of this group reported symptoms that had lasted for a 6 months (chronic subgroup). In the chronic subgroup, toothache was the most common symptom (42.2%) and oral sores the least common (7.8%). The mean pain intensity in the chronic pain subgroup was 46.6 (SD 21.7) with no age or gender differences (P > .05); 88.2% had low disability levels and 11.8% had high levels. 81.4% had low LEN scores and 18.6% had high scores, with no age/gender differences (P > .05). CONCLUSION: The prevalence of current/episodic orofacial pain was relatively high, whereas chronic orofacial pain was much less common. Although the intensity of chronic orofacial pain was significant, associated psychosocial disability was low, as was the level of perceived need for treatment. These findings may be related to more effective pain-coping strategies and greater acceptance of pain in this ethnic group compared to other ethnic groups.


Asunto(s)
Dolor Facial/epidemiología , Dolor Facial/psicología , Aceptación de la Atención de Salud , Perfil de Impacto de Enfermedad , Adaptación Psicológica , Adolescente , Adulto , Pueblo Asiatico/estadística & datos numéricos , Distribución de Chi-Cuadrado , Enfermedad Crónica , Estudios Transversales , Femenino , Necesidades y Demandas de Servicios de Salud , Hong Kong/epidemiología , Humanos , Masculino , Persona de Mediana Edad , Dimensión del Dolor , Prevalencia , Clase Social , Encuestas y Cuestionarios , Odontalgia/epidemiología , Odontalgia/psicología , Adulto Joven
11.
Community Dent Oral Epidemiol ; 36(5): 417-24, 2008 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-18284432

RESUMEN

OBJECTIVES: To investigate the impacts associated with orofacial pain symptoms among adult Chinese people in Hong Kong. Associations between impacts, pain characteristics and professional treatment seeking behaviour were explored. METHODS: A cross-sectional, population-based study was conducted using a telephone survey method. A sample of Cantonese-speaking Chinese people aged 18 years and over living in Hong Kong was interviewed. The questionnaire incorporated questions on recent orofacial pain experience and characteristics. Respondents with orofacial pain symptoms were asked about the consequences of the pain on various aspects of daily life and whether they had sought treatment for the pain. RESULTS: Of the 1222 survey respondents, 41.6% reported some form of orofacial pain. 79.3% of those who reported orofacial pain and about one-third of the total sample had experienced at least one impact. The most common impact was worried about oral and dental health (59.8%) followed by avoided certain food (50.4%). Respondents with toothache were found to be more likely to have experienced all the impacts investigated (OR range: 2.048-3.309). People who had stayed in bed more than usual (OR = 2.342), experienced sleep disturbance (OR = 2.149), and worried about their oral and dental health (OR = 2.851) were more likely to seek professional treatment. CONCLUSIONS: The adverse impact of orofacial pain on the well-being of the adult population of Hong Kong was substantial. Despite this, treatment seeking was low with a high level of untreated orofacial pain symptoms.


Asunto(s)
Dolor Facial/complicaciones , Aceptación de la Atención de Salud/estadística & datos numéricos , Perfil de Impacto de Enfermedad , Actividades Cotidianas , Adolescente , Adulto , Ansiedad/etiología , Reposo en Cama/efectos adversos , Estudios Transversales , Escolaridad , Femenino , Preferencias Alimentarias , Hong Kong , Humanos , Renta , Modelos Logísticos , Masculino , Persona de Mediana Edad , Trastornos del Sueño-Vigilia/etiología , Encuestas y Cuestionarios , Adulto Joven
12.
J Orofac Pain ; 21(1): 63-71, 2007.
Artículo en Inglés | MEDLINE | ID: mdl-17312643

RESUMEN

AIMS: To determine orofacial pain (OFP) characteristics, associated disability, and effect on quality of life in elderly community-dwelling Chinese people. METHODS: A cross-sectional survey involving elderly people registered with the Family Medicine Unit of the University of Hong Kong served as the sampling frame. Elderly people with recent OFP symptoms and a comparison control group without OFP participated. Standard questions were asked about OFP conditions in the previous month and the Oral Health Impact Profile (OHIP-14), General Health Questionnaire (GHQ-12), and pain-related disability questions were administered prior to a standard clinical examination. RESULTS: Ninety-five people with OFP and 100 people without OFP participated. The median number of pain symptoms per subject was 2.0. Toothache was the most common symptom (58.9%); shooting pain across the face and muscle tenderness were the least common (6.3%). More than half of the pain participants described moderate to severe OFP. The prevalences of patients with neurological/vascular (NV), musculoligamentous/soft tissue (MST), or dentoalveolar (DA) OFP were 35.8%, 33.7%, and 30.5%, respectively. Chronic OFP was common (80%). The mean OHIP-14 summary score was significantly higher in OFP subjects than controls (P < .001) and significantly higher in the MST and DA subgroups than in the NV subgroup (P < .001). GHQ scores of > or = 4, indicating greater psychological distress, were more common in OFP subjects than controls (P < .01). Twenty percent of OFP subjects indicated that their conditions interfered with daily life activities, and in 9.9% it affected ability to work. CONCLUSION: OFP had a substantial detrimental impact on daily life activities, psychological distress level, and quality of life in Chinese elders. MST and DA conditions had the greatest adverse impact on quality of life.


Asunto(s)
Dolor Facial/clasificación , Calidad de Vida , Actividades Cotidianas , Anciano , Actitud Frente a la Salud , China/etnología , Estudios Transversales , Músculos Faciales/fisiopatología , Dolor Facial/psicología , Femenino , Cefalea/clasificación , Cefalea/psicología , Hong Kong , Humanos , Masculino , Persona de Mediana Edad , Enfermedades de la Boca/clasificación , Enfermedades de la Boca/psicología , Dimensión del Dolor , Parestesia/clasificación , Parestesia/psicología , Características de la Residencia , Estrés Psicológico/clasificación , Estrés Psicológico/psicología , Trastornos de la Articulación Temporomandibular/clasificación , Trastornos de la Articulación Temporomandibular/psicología , Enfermedades Dentales/clasificación , Enfermedades Dentales/psicología , Odontalgia/clasificación , Odontalgia/psicología , Trabajo
13.
Cancer ; 109(7): 1344-54, 2007 Apr 01.
Artículo en Inglés | MEDLINE | ID: mdl-17326045

RESUMEN

BACKGROUND: Radiotherapy (RT) promises optimistic results in the treatment of nasopharyngeal cancer (NPC). The objective of the current study was to map out prospectively the impact of NPC and RT on patients from diagnosis to 1 year posttreatment. METHODS: For this study, 67 Chinese patients (46 men and 21 women) with newly diagnosed stage I or II NPC who received primary RT were recruited. Physical and psychosocial adjustments were measured by using the Rotterdam Symptom Checklist, Beck Anxiety Inventory, Beck Depression Inventory, Perceived Stress Scale, and the 36-item Short-Form Health Survey (SF-36). Semistructured clinical interviews were conducted at bimonthly intervals from pre-RT to 1 year post-RT. RESULTS: Physical and psychosocial adjustments were poorest from pre-RT to the end of RT. Rapid improvements in all areas were noted in the first 2 months post-RT and reached a plateau at around the 6th month. At 1 year, except for physical symptoms and perceived stress, patient measures recovered to their pre-RT levels. At 1 year, patients had more physical complaints (P < .001) but less perceived stress (P = .002). The percentage of patients who expressed fear of dying dropped from 28% pre-RT to 2% at 1 year. However, patients who expressed "fear of the worst happening" increased from 51% pre-RT to 57% at 1 year. CONCLUSIONS: Different periods in treatment of NPC imposed different psychosocial demands on patients. The current results indicated that the period from diagnosis to 2-month post-RT was a high-risk period both physically and emotionally. After treatment, most patients showed resilience despite persistent side effects of RT and successfully resumed their pretreatment level of functioning by the end of the year. Despite resuming a normal or near-normal living, patients still noted a subdued fear of recurrence.


Asunto(s)
Carcinoma de Células Escamosas/psicología , Carcinoma de Células Escamosas/radioterapia , Neoplasias Nasofaríngeas/psicología , Neoplasias Nasofaríngeas/radioterapia , Calidad de Vida/psicología , Adulto , Anciano , China/epidemiología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Satisfacción del Paciente , Estudios Prospectivos
14.
Int J Radiat Oncol Biol Phys ; 66(4): 981-91, 2006 Nov 15.
Artículo en Inglés | MEDLINE | ID: mdl-17145528

RESUMEN

PURPOSE: To compare directly the effect of intensity-modulated radiotherapy (IMRT) vs. conventional radiotherapy (CRT) on salivary flow and quality of life (QoL) in patients with early-stage nasopharyngeal carcinoma (NPC). METHODS AND MATERIALS: Fifty-one patients with T2, N0/N1, M0 NPC took part in a randomized controlled clinical study and received IMRT or CRT. Stimulated whole (SWS) and parotid (SPS) saliva flow were measured and Medical Outcomes Short Form 36 (SF-36), European Organization for Research and Treatment of Cancer (EORTC) core quetionnaire, and EORTC head-and-neck module (QLQ-H&N35) were completed at baseline and 2, 6, and 12 months after radiotherapy. RESULTS: Forty-six patients (88%) were in disease remission 12 months after radiotherapy. At 12 months postradiotherapy, 12 (50.0%) and 20 patients (83.3%) in the IMRT group had recovered at least 25% of preradiotherapy SWS and SPS flow respectively, compared with 1 (4.8%) and 2 patients (9.5%), respectively, in the CRT group. Global health scores showed continuous improvement in QoL after both treatments (p < 0.001). However, after 12 months subscale scores for role-physical, bodily pain, and physical function were significantly higher in the IMRT group, indicating a better condition (p < 0.05). Dry mouth and sticky saliva were problems in both groups 2 months after treatment. In the IMRT group, there was consistent improvement over time with xerostomia-related symptoms significantly less common than in the CRT group at 12 months postradiotherapy. CONCLUSIONS: IMRT was significantly better than CRT in terms of parotid sparing and improved QoL for early-stage disease. The findings support the case for assessment of health-related QoL in relation to head-and-neck cancer using a site-specific approach.


Asunto(s)
Neoplasias Nasofaríngeas/radioterapia , Calidad de Vida , Traumatismos por Radiación/etiología , Traumatismos por Radiación/prevención & control , Radioterapia Conformacional/efectos adversos , Xerostomía/etiología , Xerostomía/prevención & control , Adulto , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Neoplasias Nasofaríngeas/complicaciones , Proyectos Piloto , Medición de Riesgo , Factores de Riesgo , Resultado del Tratamiento
15.
J Orofac Pain ; 20(3): 218-25, 2006.
Artículo en Inglés | MEDLINE | ID: mdl-16913431

RESUMEN

AIMS: To estimate the prevalence and pattern of self-reported orofacial pain symptoms and treatment-seeking behavior in adult Cantonese-speaking Chinese people in Hong Kong. METHODS: A cross-sectional population survey involving a telephone survey technique was used to identify 1,222 randomly selected Cantonese-speaking people aged at least 18 years. Standard questions were asked on the experience of 8 orofacial pain symptoms in the previous month and on treatment-seeking behavior. RESULTS: Orofacial pain symptoms were reported by 41.6% of respondents when tooth sensitivity was included and by 24.2% when it was excluded. There was no gender- or age-related difference in pain prevalence (P > .010). Tooth sensitivity was the most common symptom (27.7%), followed by toothache (12.5%), and shooting pain in the face was the least common (1.1%). Almost half those with symptoms reported the pain as moderate to severe, and a fifth had frequent pain. Only 20.3% with pain symptoms sought professional treatment, and use of self-prescribed medication was very low (12.4%). CONCLUSION: Orofacial pain symptoms appear to affect more than a quarter of the adult population in Hong Kong, and prevalence estimates were consistent with those in Western countries. A substantial proportion of the pain symptoms were frequent and of moderate to severe intensity, with the potential for significant morbidity. Professional treatment seeking was very low and may be related to specific pain behaviors and effective coping strategies in this ethnic group.


Asunto(s)
Dolor Facial/epidemiología , Aceptación de la Atención de Salud/estadística & datos numéricos , Adolescente , Adulto , Distribución por Edad , Pueblo Asiatico/estadística & datos numéricos , Dolor Facial/terapia , Femenino , Hong Kong/epidemiología , Humanos , Masculino , Persona de Mediana Edad , Distribución por Sexo , Odontalgia/epidemiología , Odontalgia/terapia
16.
Head Neck ; 28(8): 712-22, 2006 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-16475203

RESUMEN

BACKGROUND: Xerostomia is a ubiquitous complication after conventional radiotherapy for nasopharyngeal carcinoma (NPC) that seriously impairs patient quality of life (QOL). The effect on QOL of parotid-sparing intensity-modulated radiotherapy (IMRT) for early-stage NPC was assessed prospectively. METHODS: Thirty-two patients with T1-2,N0-1,M0 NPC received IMRT. Saliva flow was measured, and the Medical Outcomes Short Form 36 (SF-36), European Organization for Research and Treatment of Cancer (EORTC) core, and EORTC head and neck module (QLQ-H&N35) questionnaires were completed at baseline and 2, 6, and 12 months after IMRT. RESULTS: Saliva flow recovered to at least 25% of baseline in most cases after 1 year. Physical function, fatigue, and vitality were problems at 2 months and then resolved (p < or = .002). Global health scales showed continuous improvement in QOL after treatment (p < or = .004). Xerostomia and sticky saliva were problems 2 months after treatment; thereafter, continuous improvement occurred (p < or = .001). Xerostomia scores correlated with general aspects of QOL (p < or = .044). CONCLUSION: IMRT for early-stage disease preserved key aspects of QOL, and a reduction in xerostomia symptoms enhanced broader aspects of QOL.


Asunto(s)
Neoplasias Nasofaríngeas/radioterapia , Calidad de Vida , Radioterapia de Intensidad Modulada , Adulto , Femenino , Indicadores de Salud , Humanos , Persona de Mediana Edad , Neoplasias Nasofaríngeas/patología , Neoplasias Nasofaríngeas/cirugía , Estadificación de Neoplasias , Glándula Parótida/efectos de la radiación , Estudios Prospectivos , Dosificación Radioterapéutica , Salivación/efectos de la radiación , Xerostomía/prevención & control
17.
Oral Oncol ; 42(8): 842-8, 2006 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-16455288

RESUMEN

A comparison was made of Oral Balance gel delivered by slow release via a novel intra-oral device versus an oral bolus of gel on the oral health condition and oral health-related quality of life (OHRQoL) in patients who had received standard head and neck irradiation for nasopharyngeal carcinoma. Twenty-two participants took part in a randomized single-blind crossover clinical study. Each treatment lasted 4 weeks with an intervening 4 weeks washout period. The GOHAI, Xerostomia Inventory and patient satisfaction measures were self-completed and oral health condition assessed objectively at baseline (week 0) and weeks 4, 8 and 12. Oral Balance gel, in bolus and slow-release forms, was effective in improving aspects of oral health, notably a reduction in oral cariogenic micro-organisms. Slow release of gel via the intra-oral device did not appear to improve OHRQoL whereas gel alone reduced the severity of xerostomia symptoms and was the treatment of choice.


Asunto(s)
Neoplasias Nasofaríngeas/radioterapia , Polímeros/administración & dosificación , Traumatismos por Radiación/terapia , Saliva Artificial/administración & dosificación , Xerostomía/terapia , Adulto , Anciano , Estudios Cruzados , Preparaciones de Acción Retardada , Femenino , Geles , Indicadores de Salud , Humanos , Masculino , Persona de Mediana Edad , Satisfacción del Paciente , Calidad de Vida , Traumatismos por Radiación/etiología , Traumatismos por Radiación/fisiopatología , Salivación , Índice de Severidad de la Enfermedad , Método Simple Ciego , Resultado del Tratamiento , Xerostomía/etiología , Xerostomía/fisiopatología
18.
Int Dent J ; 55(5): 319-24, 2005 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-16245468

RESUMEN

AIM: To investigate the oral health of elderly stroke survivors on discharge from hospital into the community after rehabilitation and six months later compared with community dwelling elderly people without stroke. METHOD: The study took place in the rehabilitation unit of a general medical hospital in Hong Kong. It was a longitudinal study involving 43 elderly survivors of mild to moderate stroke about to be discharged from hospital after rehabilitation and a comparison group of 43 community-dwelling elderly people. Verified clinical examination techniques and measures were used to assess dental caries, periodontal disease, oral hygiene, oral candidiasis, prosthetic status/need and functional disability (Barthel Index [BI]). Socio-demographic information was also collected. RESULTS: Stroke survivors had significantly higher plaque and bleeding scores on hospital discharge and after six months compared with the control group (p<0.01). On hospital discharge, the stroke group also had a poorer periodontal condition with more 4-5mm pockets. The mean BI on hospital admission was 71 and 91 on discharge. Stroke survivors with a higher BI on discharge had lower plaque scores after six months. The tooth condition, number of functional tooth pairs, prosthetic status, presence of oral candidiasis and oral yeast carriage were similar between stroke and comparison groups. CONCLUSIONS: Despite significant objective improvement in functional ability after stroke, elderly survivors returning to the community had significantly poorer periodontal health compared with community dwelling elderly without stroke, and the situation did not improve dramatically over six months. The protracted recovery of hand, arm and oral sensori-motor function is the most likely cause.


Asunto(s)
Salud Bucal , Accidente Cerebrovascular/complicaciones , Sobrevivientes , Anciano , Índice de Placa Dental , Métodos Epidemiológicos , Femenino , Humanos , Masculino , Rehabilitación de Accidente Cerebrovascular
19.
Community Dent Health ; 22(3): 156-61, 2005 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-16161879

RESUMEN

OBJECTIVES: To investigate the relationship between tooth loss, denture wearing and oral health-related quality of life (OHQoL) among community-dwelling elderly people in Hong Kong. METHODS: A questionnaire study of elderly people aged 60-80 years who were recruited at neighborhood social centres for the elderly. The Chinese version of the General Oral Health Assessment Index (GOHAI) was used and information about natural tooth number and denture wearing were obtained. RESULTS: 233 elderly subjects were recruited and interviewed. Around 20% of the partially dentate subjects had their last tooth loss within the previous year and a quarter within the last five years. Significantly fewer edentulous subjects had their last tooth loss within the previous year (3%) and within the last five years (12%, p < 0.001). Twenty two percent of the subjects had difficulty in accepting tooth loss. More edentulous subjects (69%) were satisfied with their dentures than partially dentate denture wearers (37%, p < 0.001). Edentulous elderly subjects had a higher mean GOHAI score (53.0) than partially dentate denture wearers (49.1, p < 0.001). Results from a multiple factor ANOVA revealed that elderly subjects who had loose teeth, difficulty in accepting tooth loss and were not satisfied with their removable dentures had a lower mean GOHAI score. CONCLUSIONS: In general, tooth loss and denture wearing did not have a major impact on OHQoL in elderly Chinese people. However, partially dentate denture wearers experienced a greater adverse impact on OHQoL than edentulous subjects most probably due to less satisfaction with their dentures and discomfort associated with loose teeth.


Asunto(s)
Dentaduras/psicología , Calidad de Vida , Pérdida de Diente/psicología , Anciano , Anciano de 80 o más Años , Análisis de Varianza , Femenino , Hong Kong , Humanos , Masculino , Persona de Mediana Edad , Salud Bucal , Perfil de Impacto de Enfermedad , Estadísticas no Paramétricas
20.
Clin Oral Investig ; 9(3): 148-53, 2005 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-15895267

RESUMEN

Management of radiotherapy-related xerostomia is difficult. Saliva substitutes are helpful but the effects are short-lived. The purpose of the study was to develop a prototype intra-oral lubricating device for the management of radiotherapy-related xerostomia and to evaluate patient acceptance. An intra-oral lubricating device was fabricated that incorporated a reservoir in the palatal vault and permitted slow release of saliva substitute by the patient. Preliminary clinical testing was done in five patients with radiotherapy-related xerostomia. A measure incorporating seven questions was used to explore patient acceptance. The device was simple to fabricate using materials available in a technical laboratory. All patients were able to wear the device for at least 4 h per day throughout the test period. The device was considered easy to use and clean. Some impairment of speech and chewing was noted although this appeared to be related to the bulkiness of the reservoir. General oral comfort was improved due to the lubricating effect. The bulk of the reservoir was reduced as a consequence of patient feedback. The design addressed key problems associated with previous lubricating systems. Patient reports on oral functioning with the device in situ provided pivotal information on the device's utility.


Asunto(s)
Irradiación Craneana/efectos adversos , Sistemas de Liberación de Medicamentos/instrumentación , Saliva Artificial/administración & dosificación , Xerostomía/terapia , Diseño de Equipo , Femenino , Humanos , Lubrificación , Masculino , Persona de Mediana Edad , Satisfacción del Paciente , Proyectos Piloto , Encuestas y Cuestionarios , Xerostomía/etiología
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