Thermal stratification effect on gravity driven transport of hybrid CNTs down a stretched surface through porous medium.

The purpose of the current article is to explore the impact of thermal stratification and medium porosity on gravity-coerced transport of hybrid carbon nanotubes down an upright extending sheet inspired by a constant applied magnetic field along with heat transfer investigation in existence of thermal radiation, viscous dispersal, and joule heating effect. Rectangular coordinates are chosen for the mathematical interpretation of the governing flow problem. Homothetic analysis is employed for the sake of simplification process. The reduced system of coupled nonlinear differential equations is dealt numerically by dint of computational software MATLAB inbuilt routine function Bvp4c. The numerical investigation is carried out for the distinct scenarios namely, ( i ) Presence of favorable buoyancy force, ( i i ) Case of purely forced convection and ( i i i ) Presence of opposing buoyancy force. Significant Findings: The key findings include that the presence of hybrid carbon nanotubes and medium porosity contributes significantly to upsurging surface shear stress magnitude whereas, external magnetic field and velocity slip effects in an altered manner. The present study may be a benchmark in study of fueling process in space vehicles and space technology.

Heat transport in inclined flow towards a rotating disk under MHD.

Flow towards a rotating disk is of highly practical significance in numerous engineering applications such as Turbine disks, rotary type machine systems and many more. In light of this, the current work is an attempt to explore MHD oblique flow towards a rotating disk. Hydromagnetic effects in addition to heat transfer is taken into consideration. The flow governing Partial Differential Equations are altered to a system to coupled non-linear Ordinary Differential Equations through scaling group of transformations which afterwards are tackled using Shooting Algorithm. The impact of obliqueness parameter γ, rotation ratio parameter [Formula: see text] and magnetic field parameter M on 2-dimensional and 3-dimensional stream contours are presented. Location of the shear center varies with magnetic field parameter. Heat flow at the disk surface boosts with magnet field parameter M and rotation ratio parameter [Formula: see text].

MicroRNA Regulation Along the Course of Cellular Reprogramming to Pluripotency.

Generation of patient-specific stem cells has been a long-held aim of many developmental biologists. Apart from providing a source for stem cell therapies, these cells have the potential to be utilized in a number of scenarios like disease modeling, drug screening and studying normal development. Various approaches have been used to reprogram terminally differentiated cells to a pluripotent state with varying efficiencies and limitations. The nuclear transfer had been the most successful method for reprogramming until recently. Shinya Yamanaka in 2006 published a seminal study wherein, by using a cocktail of stem cell transcription factors famously called Yamanaka factors, the differentiated cells were reprogrammed to a pluripotent state. These cells, called induced pluripotent stem (iPS) cells, were later generated by various laboratories using a different combination of molecules. Importantly, induced pluripotency is a state that is achieved in a stepwise manner with landmark steps. Various molecules including microRNAs (miRNAs) are activated or repressed at these steps to ensure a successful transition to pluripotency. The precise regulation of miRNAs is important as they collectively regulate myriads of mRNAs representing specific pathways important for steering cellular fate towards stemness. Owing to their significance, miRNAs have been constituents of cocktails used for iPSCs generation. This review aims at discussing the stepwise regulation of miRNAs and their significance along the path to reprogramming.

Impact of viscosity variation and micro rotation on oblique transport of Cu-water fluid.

This study inspects the influence of temperature dependent viscosity on Oblique flow of micropolar nanofluid. Fluid viscosity is considered as an exponential function of temperature. Governing equations are converted into dimensionless forms with aid of suitable transformations. Outcomes of the study are shown in graphical form and discussed in detail. Results revealed that viscosity parameter has pronounced effects on velocity profiles, temperature distribution, micro-rotation, streamlines, shear stress and heat flux. It is found that viscosity parameter enhances the temperature distribution, tangential velocity profile, normal component of micro-rotation and shear stress at the wall while it has decreasing effect on tangential component of micro-rotation and local heat flux.