1.
Am Surg
; 84(9): e375-e377, 2018 Sep 01.
Artículo
en Inglés
| MEDLINE
| ID: mdl-30269712
Asunto(s)
Fallo Renal Crónico/complicaciones , Trasplante de Riñón/métodos , Donadores Vivos , Obesidad/complicaciones , Receptores de Trasplantes , Salud Global , Supervivencia de Injerto , Humanos , Incidencia , Fallo Renal Crónico/cirugía , Obesidad/epidemiología , Factores de Riesgo , Resultado del Tratamiento
2.
Biol Chem
; 398(9): 995-1007, 2017 08 28.
Artículo
en Inglés
| MEDLINE
| ID: mdl-28095368
RESUMEN
Iron is an essential element required for many processes within the cell. Dysregulation in iron homeostasis due to iron overload is detrimental. This nutrient is postulated to contribute to the initiation of cancer; however, the mechanisms by which this occurs remain unclear. Defining how iron promotes the development of ovarian cancers from precursor lesions is essential for developing novel therapeutic strategies. In this review, we discuss (1) how iron overload conditions may initiate ovarian cancer development, (2) dysregulated iron metabolism in cancers, (3) the interplay between bacteria, iron, and cancer, and (4) chemotherapeutic strategies targeting iron metabolism in cancer patients.