RESUMEN
A dor abdominal no paciente com lúpus eritematoso sistêmico tem amplo espectro clínico, variando desde condições inespecí- ficas, como diarreia e vômitos, até eventos de importante morbi- mortalidade, como o abdome agudo inflamatório e/ou perfura- tivo. A seguir, descreve-se um caso de paciente do sexo feminino, de 23 anos, internada por dor abdominal associada a vômitos e à diarreia crônica e progressiva. Foi diagnosticada com lúpus eritematoso sistêmico há 2 anos. Durante a internação, evoluiu com quadro de abdome agudo, e foi realizada tomografia compu- tadorizada de abdome, revelando importante edema de parede intestinal difuso. Isso, somado a alterações clínico-laboratoriais, permitiu o diagnóstico de enterite lúpica. Foi realizado tratamen- to conservador, com corticoterapia e terapia de suporte com correção de distúrbios eletrolíticos severos, sendo iniciado ciclo- fosfamida, com resolução dos sintomas gastrintestinais.
Abdominal pain in patients with systemic lupus erythematosus has a broad clinical spectrum, ranging from nonspecific symp- toms, such as diarrhea and vomiting, to events of significant morbidity and mortality, such as acute inflammatory and/or per- forating abdomen. This article describes a case of a 23-year-old female patient hospitalized for abdominal pain, associated with vomiting and progressive chronic diarrhea. She was diagnosed with systemic lupus erythematosus 2 years ago. During hospita- lization, the patient progressed with acute abdomen, and an ab- dominal computed tomography scan was performed, revealing major diffuse intestinal wall edema. This, added to clinical and laboratories alterations, allowed the diagnosis of lupus enteritis. A conservative treatment with corticotherapy and supportive therapy with correction of severe electrolyte disturbances were initiated, as well as the prescription of cyclophosphamide, with resolution of gastrointestinal symptoms.
Asunto(s)
Humanos , Femenino , Adulto Joven , Enteritis/etiología , Lupus Eritematoso Sistémico/complicaciones , Vómitos/etiología , Desequilibrio Hidroelectrolítico/terapia , Tomografía Computarizada por Rayos X , Dolor Abdominal/etiología , Ultrasonografía , Corticoesteroides/uso terapéutico , Enfermedades Raras/etiología , Diarrea/etiología , Enteritis/diagnóstico , Enteritis/tratamiento farmacológico , Administración Intravenosa , Combinación Piperacilina y Tazobactam/uso terapéutico , Antiinflamatorios/uso terapéutico , Antibacterianos/uso terapéuticoRESUMEN
Pitted keratolysis is a skin disorder that affects the stratum corneum of the plantar surface and is caused by Gram-positive bacteria. A 30-year-old male presented with small punched-out lesions on the plantar surface. A superficial shaving was carried out for scanning electron microscopy. Hypokeratosis was noted on the plantar skin and in the acrosyringium, where the normal elimination of corneocytes was not seen. At higher magnification (x 3,500) bacteria were easily found on the surface and the described transversal bacterial septation was observed.
Asunto(s)
Infecciones por Corynebacterium/patología , Dermatosis del Pie/microbiología , Dermatosis del Pie/patología , Enfermedades Cutáneas Bacterianas/patología , Adulto , Epidermis/patología , Humanos , Queratosis/microbiología , Queratosis/patología , Masculino , Microscopía Electrónica de RastreoRESUMEN
Introdução: os cânceres de pele são reconhecidamente relacionados à exposição solar que, associada à suscetibilidade individual à radiação ultravioleta, constitui o fator de risco mais importante para o desenvolvimento da doença. Objetivos: relacionar o uso de protetor solar diário ou eventual com conhecimento da relação causal entre o sol e o câncer de pele, tal como a presença ou ausência de lesão de pele suspeita de neoplasia maligna em relação ao conhecimento sobre a relação supracitada. Métodos: um estudo analítico transversal foi realizado através da aplicação de 107 questionários aos participantes da Campanha de Prevenção ao câncer de pele realizada em Morro Redondo-RS. Resultados: uso diário de fotoprotetor foi mais frequente entre as mulheres (21,49%) e a prevalência de lesão suspeita de malignidade nesse grupo foi nula, enquanto que 20,55% dos homens referiram nunca se proteger, e dentre eles o predomínio de lesões suspeitas foi de 7,47%. Observouse que 67% dos entrevistados que tem conhecimento da exposição solar como fator de risco para câncer de pele usam fotoprotetor e, entre os que desconhecem a relação, 56% nunca se protegem. Foi demonstrado que 17% dos que conhecem tal relação tiveram lesão de pele suspeita e, entre os que desconhecem, apenas 1% obteve o mesmo diagnóstico. Conclusão: o uso de fotoprotetor mostrou-se indispensável para prevenção de lesão de pele e este deve ser orientado corretamente. Portanto, campanhas de prevenção ao câncer de pele são importantes para a conscientização da população sobre proteção solar, devendo ser estimuladas.
Introduction: Skin cancers are known to be related to sun exposure, which, associated with individual susceptibility to ultraviolet radiation, is the major risk factor for developing the disease. Aims: To relate the daily or occasional use of sunscreen with awareness of the causal relationship between sun and skin cancer, such as the presence or absence of skin lesions suspected of malignancy in relation to the knowledge of the above-mentioned relationship. Methods: A cross-sectional analytical study was carried out by administering 107 questionnaires to participants of the Skin Cancer Prevention Campaign held in Morro Redondo, RS. Results: Daily use of sunscreen was more frequent among women (21.49%) and the prevalence of suspected malignant lesions in this group was zero, while 20.55% of men reported they never used it, and among them the predominance of suspicious lesions was 7.47%. It was found that 67% of respondents who are aware of sun exposure as a risk factor for skin cancer use sunscreen, and among those who are unaware of the relationship, 56% never protect themselves. It has been shown that 17% of those who are aware of this relationship did have a suspicious skin lesion, and among those who are unaware only 1% got the same diagnosis. Conclusion: Sunscreen use was shown to be essential for preventing skin damage and must be correctly oriented. Therefore, skin cancer prevention campaigns are important for raising public awareness about sun protection and should be encouraged.
Asunto(s)
Humanos , Masculino , Femenino , Neoplasias Cutáneas/prevención & control , Promoción de la SaludRESUMEN
Abstract Pitted keratolysis is a skin disorder that affects the stratum corneum of the plantar surface and is caused by Gram-positive bacteria. A 30-year-old male presented with small punched-out lesions on the plantar surface. A superficial shaving was carried out for scanning electron microscopy. Hypokeratosis was noted on the plantar skin and in the acrosyringium, where the normal elimination of corneocytes was not seen. At higher magnification (x 3,500) bacteria were easily found on the surface and the described transversal bacterial septation was observed.