1.
Org Lett
; 26(15): 3241-3246, 2024 Apr 19.
Artículo
en Inglés
| MEDLINE
| ID: mdl-38578088
RESUMEN
Herein, we report an electrochemical protocol for the dicarboxylation of aryl alkynes using CO2. With a graphite rod as the cathode and Al as the sacrificial anode, a series of valuable butenedioic acids are obtained in moderate to excellent yields with an E/Z ratio up to 50:1. This method features high E-selectivity, high step and atom economy, easy scalability, and a nice substrate scope, which renders it appealing for promising applications in organic synthesis and materials chemistry.