Evaluating the effect of functionally graded materials on bone remodeling around dental implants.

OBJECTIVES: This study evaluates the potential for osseointegration and remodeling of customized dental implants made from Titanium-Hydroxyapatite Functionally Graded Material (Ti-HAP FGM) with optimized geometry, using the finite element method (FEM). METHODS: The study utilized CT scan images to model and assemble various geometrical designs of dental implants in a mandibular slice. The mechanical properties of Ti-HAP FGMs were computed by varying volume fractions (VF) of hydroxyapatite (0-20%), and a bone remodeling algorithm was used to evaluate the biomechanical characteristics of the ultimate bone configuration in the peri-implant tissue. RESULTS: The findings of the FEA reveal that osseointegration improves with changes in the density and mechanical properties of the bone surrounding Ti-HAP implants, which are influenced by the varying VF of hydroxyapatite in the FGM. SIGNIFICANCE: Increasing the hydroxyapatite fraction improves osseointegration, and appropriate length and diameter selection of Ti-HAP dental implants contribute to their stability and longevity.

Biomechanical performance of resin composite on dental tissue restoration: A finite element analysis.

This study investigates the biomechanical performance of various dental materials when filled in different cavity designs and their effects on surrounding dental tissues. Finite element models of three infected teeth with different cavity designs, Class I (occlusal), Class II mesial-occlusal (MO), and Class II mesio-occluso-distal (MOD) were constructed. These cavities were filled with amalgam, composites (Young's moduli of 10, 14, 18, 22, and 26 GPa), and glass carbomer cement (GCC). An occlusal load of 600 N was distributed on the top surface of the teeth to carry out simulations. The findings revealed that von Mises stress was higher in GCC material, with cavity Class I (46.01 MPa in the enamel, 23.61 MPa in the dentin), and for cavity Class II MO von Mises stress was 43.64 MPa, 39.18 MPa in enamel and dentin respectively, while in case of cavity Class II MOD von Mises stress was 44.67 MPa in enamel, 27.5 in the dentin. The results showed that higher stresses were generated in the non-restored tooth compared to the restored one, and increasing Young's modulus of restorative composite material decreases stresses in enamel and dentin. The use of composite material showed excellent performance which can be a good viable option for restorative material compared to other restorative materials.

Mechanical influence of tissue scaffolding design with different geometries using finite element study.

The mechanical properties of tissue scaffolds are essential in providing stability for tissue repair and growth. Thus, the ability of scaffolds to withstand specific loads is crucial for scaffold design. Most research on scaffold pores focuses on grids with pore size and gradient structure, and many research models are based on scaffolding with vertically arranged holes. However, little attention is paid to the influence of the distribution of holes on the mechanical properties of the scaffold. To address this gap, this research investigates the effect of pore distribution on the mechanical properties of tissue scaffolds. The study involves four types of scaffold designs with regular and staggered pore arrangements and porosity ranging from 30% to 80%. Finite element analysis (FEA) was used to compare the mechanical properties of different scaffold designs, with von-Mises stress distribution maps generated for each scaffold. The results show that scaffolds with regular vertical holes exhibit a more uniform stress distribution and better mechanical performance than those with irregular holes. In contrast, the scaffold with a staggered arrangement of holes had a higher probability of stress concentration. The study emphasized the importance of balancing porosity and strength in scaffold design.

Design and Development of Tantalum and Strontium Ion Doped Hydroxyapatite Composite Coating on Titanium Substrate: Structural and Human Osteoblast-like Cell Viability Studies.

In order to reduce the loosening of dental implants, surface modification with hydroxyapatite (HA) coating has shown promising results. Therefore, in this present study, the sol-gel technique has been employed to form a tantalum and strontium ion-doped hybrid HA layer coating onto the titanium (Ti)-alloy substrate. In this study, the surface modification was completed by using 3% tantalum pent oxide (Ta2O5), 3% strontium (Sr), and a combination of 1.5% Ta2O5 and 1.5% Sr as additives, along with HA gel by spin coating technique. These additives played a prominent role in producing a porous structure layer coating and further cell growth. The MG63 cell culture assay results indicated that due to the incorporation of strontium ions along with tantalum embedded in HA, cell proliferation increased significantly after a 48 h study. Therefore, the present results, including microstructure, crystal structure, binding energy, and cell proliferation, showed that the additives 1.5% Ta2O5 and 1.5% Sr embedded in HA on the Ti-substrate had an optimized porous coating structure, which will enhance bone in-growth in surface-modified Ti-implants. This material had a proper porous morphology with a roughness profile, which may be suitable for tissue in-growth between a surface-modified textured implant and bone interface and could be applicable for dental implants.

Biomechanical analysis of printable functionally graded material (FGM) dental implants for different bone densities.

The long-term success of a dental implant is related to the material and design of the implant, and bone density. Conventional implants cause stress-shielding due to a mismatch between the implant and bone stiffness. Functionally graded porous materials and designs are a great choice for the design of implants to control the local stiffness at a certain location to meet the biomechanical requirements. The purpose of this study is to analyze five designs of axial and radial functionally graded materials (FGM) implants besides the conventional implant and conical and cylindrical shapes that were simulated with five different bone densities. The results showed that strain in bone increased with a decrease in cancellous bone density. The shape of the implant did not play an important role in strain/stress distribution. Conventional implants showed optimal strain (1000-2240 µÎµ) in low-density (0.7-0.8 g/cm3) bone, however, FGM implants produced optimal strain (990-1280 µÎµ) in the high-density bone (0.9-1 g/cm3) as compared to conventional implants. The proposed designs of FGM implants have the potential to address the complications of conventional implants in high-density bone.

Biomechanical performance of Ti-PEEK dental implants in bone: An in-silico analysis.

Stress-shielding is caused by a significant mismatch in stiffness between bone tissue and Ti alloy dental implants. Therefore, in this study, a Ti-PEEK composite implant was examined and compared with conventional titanium, to determine the behavior of the host bone. Twelve 3D finite element models were modeled with two conditions of marginal cortical bone (with and without marginal bone loss). Six implant designs were constructed. Implant (A) was made with a conventional design (dense titanium), implants (B), (C) and (D) are designed with Ti-PEEK composite (outer layer made of PEEK and inner structures made of Ti with hexagonal, cylindrical, and cross shapes for implants (B), (C) and (D), respectively), the implant (E) is designed with Ti at the upper half section and PEEK at the bottom half section, and the implant (F) is designed with PEEK at the upper half section and Ti at the bottom half section. An axial load of 200 N was applied to the buccal cusp and central fossa of the occlusal surface. The displacements, stress, and equivalent strain were analyzed at the level of bone tissue. The mechanostat of Frost was used to determine the behavior of the cancellous bone under these biomechanical conditions. Results showed that strains were greater in cancellous bone with marginal bone loss than in healthy bone (w/o MBL). When compared to implants (B)-(F), conventional implant (A) did not produce as much strain. Thus, results and analyses suggest that the Ti-PEEK implants outperform compared with the implant (A) in the case of no marginal bone loss. However, the implants (A) and (E) perform equally in terms of bone loss.

Design of dental implant using design of experiment and topology optimization: A finite element analysis study.

Ever since the introduction of topology optimization into the industrial and manufacturing fields, it has been a top priority to maximize the performance of any system by optimizing its geometrical parameters to save material while keeping its functionality unaltered. The purpose of this study is to design a dental implant macro-geometry by removing expendable material using topology optimization and to evaluate its biomechanical function. Three-dimensional finite element models were created of an implant embedded in cortical and cancellous bone. Parameters like the length and diameter of the implant and the bone quality (±20% variation in Young's modulus, Poisson's ratio and density for both cortical and cancellous bone) were varied to evaluate their effect on the principal stresses induced on the peri-implant bone tissues and the micromotion of the implant at 150 N applied load. Design optimization is used to select one suitable implant for each material property combination with optimum parameters that experiences the least von Mises stress and axial deformation, out of twenty implants with different length and diameter for each material property combination. Topology optimization was then used on the selected implants to remove the redundant material. The biomechanical functions of the implants with optimized parameter and volume were then evaluated. The finite element analyses estimated that a reduction of 32% to 45% in the implant volume is possible with the implant still retaining all of its functionality.

Effect of supporting implants inclination on stability of fixed partial denture: A finite element study.

The aim of this finite element study was to analyze effect of supporting implants inclination on stress distribution in the bone for a four-unit fixed partial denture. A three-dimensional finite element model of mandibular molar section of the bone to receive implants was constructed. Three implant-supported fixed partial dentures, with null, moderate and wide tilting, of 0°, 15° and 30° implant inclinations, respectively, were modeled. A mechanical load of 10 MPa was applied in coronal-apical direction on bridge framework at the regions of crowns positions. The finite element analysis was performed, and von Mises stress levels were calculated. Peak stress concentration in the cortical bone was observed mostly around the implant necks, in inter-implants line. There was favorable stress distribution during loading, with peak stress being 90.04 MPa for 0°, which decreased to 54.33 MPa for 15° and 46.36 MPa for 30° inclination. The supporting implants inclination in fixed partial denture plays an important role in stress distribution and may be helpful in preventing bone loss and implant failure. This phenomenon is likely to be more pronounced in bones of poor quality. Within the limitation of this study, it seems that the inclination of implants in fixed partial denture has a favorable effect on stress distribution pattern values around the supporting implants.

Stress influence on orthodontic system components under simulated treatment loadings.

BACKGROUND AND OBJECTIVE: Mini-implants have been developed and effectively used by clinicians as anchorage for orthodontic tooth movement. The objective of this study was to elucidate the stress response of orthodontic forces on the periodontal system, bone tissues, mini-implant and the bracket-enamel interface. METHODS: Computer tomography images of a commercially available mini-implant, an orthodontic bracket bonded to a central incisor, and jawbone section models were used to reconstruct three dimensional computer models. These models were exported and meshed in an ABAQUSⓇ finite-element package. Material properties, multi-segment interactions, boundary and loading conditions were then applied to each component. Finite-element analyses were conducted to elucidate the effect of orthodontic force on the equivalent von Mises stress response within the simulated orthodontic system. RESULTS: The highest stress values in the orthodontic system were predicted at the mini-implant neck, at the interface of the cortical bone, and gradually decreased in the internal apical direction of the miniscrew. On the alveolar bone, the maximum stress values were located in the alveolar cortical bone near the cervical areas of the mini-implant, which is in line with clinical findings of area where bone loss was found post orthodontic tooth treatment. Another peak of von Mises stress response was found in the enamel bracket junction with a maximum up to 186.05 MPa. To ensure good bonding between the enamel and bracket, it is vital to select carefully the type and amount of bonding materials used in the bracket-enamel interface to assure an appropriate load distribution between the teeth and alveolar bone. The results also revealed the significance of the periodontal ligaments, acting as an intermediate cushion element, in the load transfer mechanism. CONCLUSIONS: This study is sought to identify the stress response in a simulated orthodontic system to minimize the failure rate of mini-implants and bracket loss during orthodontic treatment.

Finite-Element analysis of a lateral femoro-tibial impact on the total knee arthroplasty.

BACKGROUND AND OBJECTIVE: Total knee arthroplasty (TKA) is a routine surgery performed to treat patients with severe knee osteoarthritis. The success of a TKA depends strongly on the initial stability of the prosthetic components and its long-term osseointegration due to the optimal distribution of mechanical stresses in the surrounding bones under the effect of the different biomechanical loads applied to the Femur-TKA-Tibia system. The purpose of this study is to analyze the level and the distribution of the induced stresses in a Femur-TKA-Tibia system subjected to combined triaxial forces, which mimic a femoral mechanical shock. METHODS: In this study, complex TKA system implanted in both femoral and tibial bones has been analyzed numerically with a three-dimensional finite-element method. A virtual model is designed to examine in silico the effect of the combined triaxial forces acting on this prosthesis in femoral region. Anatomical three-dimensional finite-element models of both femoral and tibial bones were constructed to calculate the interfacial stresses around the TKA components. The 3D finite-element processing program ABAQUS was used to perform the analysis. RESULTS: The stresses propagated in the bone regions adjacent to the TKA osseointegrated components, and the decreased in their magnitude to the outer region. These stresses reached the highest level in the cortical bone areas that are right next to the proximal upper attachment portions of the TKA osseointegrated components. The magnitude of the stresses in the tibial component is higher than that in the femoral component. Finally, it is very important to emphasize the role of the polyethylene articulating spacer in the shock absorption of bone support sections. Thus, this component should be preserved mechanically from the impact of high shocks in order to maintain healthy TKA systems. CONCLUSIONS: Optimizing TKA model by controlling the biomechanical stresses distributed within its both components and supporting bones is a valid approach to achieving favorable long-term outcomes. The 3D finite-element analysis provides an effective pre-operative method for planning patient-specific TKA prostheses, and for designing future models that preserves the biomechanical function of the Femur-TKA-Tibia system.

A proposed health monitoring system using fuzzy inference system.

Due to the busy schedule of every human being in today's world, consciousness towards one's health has become quite alarming. A person suffering from any chronic disease needs a gradual, regular and close monitoring to recover from the disease or to be under control. Because of heavy work pressure, anxiety, change of weather and location or due to some other causes, the effect of the diseases can turn up into an appalling state. Two vital aspects of human diseases are blood pressure (hypertension) and blood sugar imbalance. Hypertension is one of the complications of prolonged untreated diabetes. Other organs like kidney, eye and peripheral nerves are also involved. The various gradations of hypertension and diabetes are required to understand for the progression of the disease and to make plan for the treatment. So these two aspects are considered in this article. The idea is to develop a logic, which could be incorporated in a pocket friendly device in future that would generate an alarm whenever there is imbalance in blood sugar or blood pressure levels. The concept of the fuzzy inference rule and first-order logic is implemented to develop this study.

Finite-Element Study of Biomechanical Explanations for Bone Loss around Dental Implants.

Since the advent of osteointegrated implantology and its precepts issued by the Swedish School, assessment of peri-implant bone loss criteria has often been debated by professionals in this field. Long-term success of dental implants is highly reliant on structural and functional osseointegration between implant and surrounding intraoral tissues. In this context, the current study aims to provide biomechanical explanations for causes of bone loss around the dental implant after osseointegration by computational analysis, using a three-dimensional finite-element (FE) method. We design an approximate virtual model that includes the smooth, cylindrical dental implant and alveolar bone. We use SolidWorks software and export to ABAQUS for computational stress analysis at the bone-implant interface. The numerical model is created and loaded with a compressive occlusal force that is applied at the top of the implant platform. We thoroughly investigate the generated FE results and stress responses of the bone-implant system. The developed model is extremely useful for indicating biomechanical phenomena in the bone-implant interface that play a key part in bone loss around the dental implant. In addition, obtained results tend to deliver an improved understanding to designers in the biomedical engineering field and in dentistry.

Stress distribution of overdenture using odd number implants - A Finite Element Study.

The objective of this study is to look at stress patterns actuated by locator connections when used to hold mandibular overdentures retained by odd number implants. Two 3D models were prepared to simulate mandibular Implant overdentures retained by three and five Implants. The geometric solid models were modelled in solid modelling software, the models were then assembled and analysed. Three different vertical loads 50N, 100N and 150N were applied on the overdenture. Stresses were assessed at the areas of implant and connection parts, Mucosa hidden overdentures, and cortical and cancellous bone adjoining the implants. The results of this examination demonstrated that the Von Mises stresses produced by applying vertical load differed by the number of Implants used to retain the overdenture. It has been observed that maximum von misses stress induced in the implant complex and the stress induced in the mucosa layer was very low. The adaptability of the overdenture material assumed a noteworthy job in circulating the load stress and twisting of all basic structure. Stress induced in overdenture is higher in three-implant when compared to five-implant retained overdenture. The stresses induced in overdenture in two models were investigated under different loading conditions, five different combinations of the bone quality and it was found that in all the cases the maximum stress has been concentrated in the implant complex, and stress induced in overdenture is low in the case of five implant retained overdenture.

Stress analysis in single molar tooth.

The human tooth faces different stresses under environments of different loading conditions, these loading produces major factors in weakness of the tooth and bone structure. The need to save natural teeth has prompted the development of novel and complex techniques in endodontology, prosthodontics and periodontology. Despite a poor long-term prognosis and some prejudice to local bone, considerable efforts have been exerted for the realization of these techniques. Nowadays, the 3D finite element analysis (FEA) is one of the more recently used techniques for stress analysis in single human tooth under different loading cases. The von Mises stress distribution indicated that the greatest effort area of tooth lies at the base of crown up to the gingival line with varying intensities in the different loading cases. The highest stress in the cortical bone was predominantly found around the cervical region of the tooth and lowest in the cancellous bone and periodontal ligament (PDL). The PDL is a soft tissue, and it could function as an intermediate cushion element which absorbs the impact force and uniformly transfers the occlusal forces into the surrounding bone.