1.
Bioorg Med Chem Lett
; 11(4): 451-2, 2001 Feb 26.
Artículo
en Inglés
| MEDLINE
| ID: mdl-11229745
RESUMEN
A modified procedure for the synthesis of Linomide is described. The synthesized drug was characterized and assessed for its in vivo antiangiogenic activity. In a murine angiogenesis assay Linomide treatment inhibited new blood vessel formation as documented by reduced microvessel area and blood volume.
