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1.
Transfus Med ; 28(5): 346-356, 2018 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-29193548

RESUMEN

OBJECTIVES: To describe the 'Resuscitation with Pre-HospItaL bLood products' trial (RePHILL) - a multi-centre randomised controlled trial of pre-hospital blood product (PHBP) administration vs standard care for traumatic haemorrhage. BACKGROUND: PHBP are increasingly used for pre-hospital trauma resuscitation despite a lack of robust evidence demonstrating superiority over crystalloids. Provision of PHBP carries additional logistical and regulatory implications, and requires a sustainable supply of universal blood components. METHODS: RePHILL is a multi-centre, two-arm, parallel group, open-label, phase III randomised controlled trial currently underway in the UK. Patients attended by a pre-hospital emergency medical team, with traumatic injury and hypotension (systolic blood pressure <90 mmHg or absent radial pulse) believed to be due to traumatic haemorrhage are eligible. Exclusion criteria include age <16 years, blood product receipt on scene prior to randomisation, Advanced Medical Directive forbidding blood product administration, pregnancy, isolated head injury and prisoners. A total of 490 patients will be recruited in a 1 : 1 ratio to receive either the intervention (up to two units of red blood cells and two units of lyophilised plasma) or the control (up to four boluses of 250 mL 0.9% saline). The primary outcome measure is a composite of failure to achieve lactate clearance of ≥20%/h over the first 2 hours after randomisation and all-cause mortality between recruitment and discharge from the primary receiving facility to non-acute care. Secondary outcomes include pre-hospital time, coagulation indices, in-hospital transfusion requirements and morbidity. RESULTS: Pilot study recruitment began in December 2016. Approval to proceed to the main trial was received in June 2017. Recruitment is expected to continue until 2020. CONCLUSIONS: RePHILL will provide high-quality evidence regarding the efficacy and safety of PHBP resuscitation for trauma.


Asunto(s)
Transfusión de Componentes Sanguíneos , Soluciones Cristaloides/administración & dosificación , Resucitación , Heridas y Lesiones/terapia , Femenino , Humanos , Masculino , Reino Unido
2.
Br J Neurosurg ; 30(5): 529-35, 2016 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-27437912

RESUMEN

OBJECT: In recent conflicts, many UK personnel sustained head injuries requiring damage-control surgery and aeromedical transfer to the UK. This study aims to examine indications, complications and outcomes of UK military casualties undergoing craniectomy and cranioplasty from conflicts in Afghanistan and Iraq. METHODS: The UK military Joint Theatre Trauma Registry (JTTR) was searched for all UK survivors in Afghanistan and Iraq between 2004 and 2014 requiring craniectomy and cranioplasty resulting from trauma. RESULTS: Fourteen decompressive craniectomies and cranioplasties were performed with blast and gunshot wounds equally responsible for head injury. Ten survivors (71%) had an Injury Severity Score (ISS) of 75, normally designated as 'unsurvivable'. Most were operated on the day of injury. Seventy-one percent received a reverse question mark incision and 7% received a bicoronal incision. Seventy-nine percent had bone flaps discarded. Overall infection rate was 43%. Acinetobacter spp was the causative organism in 50% of cases. Median Glasgow Outcome Scale (GOS) at final follow-up was 4. All casualties had a GOS score greater than 3. CONCLUSIONS: Timely neurosurgical intervention is imperative for military personnel given high survival rates in those sustaining what are designated 'un-survivable' injuries. Early decompression facilitates safe aeromedical evacuation of casualties. Excellent outcomes validate the UK military trauma system and the stepwise performance gains throughout recent conflicts however trauma registers most evolving to have specific relevance to military casualties. In high-energy trauma with contamination and soft-tissue destruction, surgery should be conducted with regard for future soft tissue reconstruction. Bone flaps should be discarded and cranioplasty performed according to local preference. Facilities receiving military casualties should have specialist microbiological input mindful of the difficulties treating unusual microbes.


Asunto(s)
Craneotomía/métodos , Craniectomía Descompresiva/métodos , Personal Militar/estadística & datos numéricos , Adolescente , Adulto , Campaña Afgana 2001- , Traumatismos por Explosión/cirugía , Traumatismos Craneocerebrales/cirugía , Femenino , Estudios de Seguimiento , Escala de Consecuencias de Glasgow , Humanos , Guerra de Irak 2003-2011 , Masculino , Estudios Retrospectivos , Colgajos Quirúrgicos , Infección de la Herida Quirúrgica/epidemiología , Análisis de Supervivencia , Resultado del Tratamiento , Reino Unido , Heridas por Arma de Fuego/cirugía , Adulto Joven
3.
Ann R Coll Surg Engl ; 97(4): 262-8, 2015 May.
Artículo en Inglés | MEDLINE | ID: mdl-26263932

RESUMEN

INTRODUCTION: The concentration of major trauma experience at Camp Bastion has allowed continuous improvements to occur in the patient pathway from the point of wounding to surgical treatment. These changes have involved clinical management as well as alterations to the physical layout of the hospital, training and decision making. Consideration of the human factors has been a major part of these improvements. METHODS: We describe the Camp Bastion patient pathway with the communication template that focused decision making at various key moments during damage control resuscitation and damage control surgery (DCR-DCS). This system identifies four key stages: 'command huddle', 'snap brief', 'sit-reps' (situation reports) and 'sign-out/debrief'. The attitude of staff to communication and decision making is also evaluated. RESULTS: Twenty cases admitted to Camp Bastion with battlefield injuries were studied from 6 September to 6 October 2012. Qualitative responses from 115 members of staff were collected. All patients were haemodynamically shocked with a median pH of 7.25 (range: 6.83-7.40) and a median of 18 units of mixed red cells and plasma were transfused. In 89% of instances, theatre staff were aware of what was required of them at the beginning of the case, 86% felt there were regular updates and 93% understood what was required of them as the case progressed. CONCLUSIONS: The evolution of the hospital at Camp Bastion has been a unique learning experience in the field of major trauma. The Defence Medical Services have responded with continuous innovation to optimise DCR-DCS for seriously injured patients. Together with the improvements in clinical care, a communication and decision making matrix was developed. Staff evaluation showed a high degree of satisfaction with the quality of communication.


Asunto(s)
Traumatismos por Explosión/terapia , Toma de Decisiones , Médicos/estadística & datos numéricos , Guías de Práctica Clínica como Asunto , Heridas por Arma de Fuego/terapia , Campaña Afgana 2001- , Afganistán , Humanos , Masculino , Medicina Militar , Encuestas y Cuestionarios
4.
J R Army Med Corps ; 161(4): 341-4, 2015 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-25645698

RESUMEN

INTRODUCTION: Trauma care delivery in England has been transformed by the development of trauma networks, and the designation of trauma centres. A specialist trauma service is a key component of such centres. The aim of this survey was to determine to which extent, and how, the new major trauma centres (MTCs) have been able to implement such services. METHODS: Electronic questionnaire survey of MTCs in England. RESULTS: All 22 MTCs submitted responses. Thirteen centres have a dedicated major trauma service or trauma surgery service, and a further four are currently developing such a service. In 7 of these 17 centres, the service is or will be provided by orthopaedic surgeons, in 2 by emergency medicine departments, in another 2 by general or vascular surgeons, and in 6 by a multidisciplinary group of consultants. DISCUSSION: A large proportion of MTCs still do not have a dedicated major trauma service. Furthermore, the models which are emerging differ from other countries. The relative lack of involvement of surgeons in MTC trauma service provision is particularly noteworthy, and a potential concern. The impact of these different models of service delivery is not known, and warrants further study.


Asunto(s)
Atención a la Salud/organización & administración , Centros Traumatológicos , Inglaterra , Humanos , Encuestas y Cuestionarios , Recursos Humanos
5.
J R Army Med Corps ; 161(1): 36-41, 2015 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-24698844

RESUMEN

INTRODUCTION: Modern body armour clearly reduces injury incidence and severity, but evidence to actually objectively demonstrate this effect is scarce. Although the Joint Theatre Trauma Registry (JTTR) alone cannot relate injury pattern to body armour coverage, the addition of computerised Surface Wound Mapping (SWM) may enable this utility. METHOD: Surface wound locations of all UK and NATO coalition soldiers, Afghan National Army and Police and local nationals injured by explosively propelled fragments and treated in the Role 3 UK-led Field Hospital in Camp Bastion, Afghanistan, between 8 July and 20 October 2012 were prospectively recorded. The Abbreviated Injury Scores (AIS) and relative risk of casualties sustaining injuries under a type of body armour were compared with those that did not wear that armour. RESULTS: Casualties wearing a combat helmet were 2.7 times less likely to sustain a fragmentation wound to the head than those that were unprotected (mean AIS of 2.9 compared with 4.1). Casualties wearing a body armour vest were 4.1 times less likely to sustain a fragmentation wound to the chest or abdomen than those that were unprotected (mean AIS of 2.9 compared with 3.9). Casualties wearing pelvic protection were 10 times less likely to sustain a fragmentation wound to the pelvis compared with those that were unprotected (mean AIS of 3.4 compared with 3.9). DISCUSSION: Computerised SWM has objectively demonstrated the ability of body armour worn on current operations in Afghanistan to reduce wound incidence and severity. We recognise this technique is limited in that it only records the surface wound location and may be specific to this conflict. However, gathering electronic SWM at the same time as recording injuries for the JTTR was simple, required little extra time and therefore we would recommend its collection during future conflicts.


Asunto(s)
Traumatismos por Explosión/prevención & control , Diseño Asistido por Computadora , Personal Militar , Traumatismos Ocupacionales/prevención & control , Equipos de Seguridad , Escala Resumida de Traumatismos , Campaña Afgana 2001- , Diseño de Equipo , Explosiones , Humanos , Traumatismos Ocupacionales/epidemiología , Proyectos Piloto , Estudios Prospectivos , Reino Unido
6.
J R Army Med Corps ; 161(1): 9-13, 2015 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-24109105

RESUMEN

INTRODUCTION: Prevention against head wounds from explosively propelled fragments is currently the Mark 7 general service combat helmet, although only limited evidence exists to define the coverage required for the helmet to adequately protect against such a threat. The Royal Centre for Defence Medicine was tasked by Defence Equipment and Support to provide a framework for determining the optimum coverage of future combat helmets in order to inform the VIRTUS procurement programme. METHOD: A systematic review of the literature was undertaken to identify potential solutions to three components felt necessary to define the ideal helmet coverage required for protection against explosively propelled fragments. RESULTS: The brain and brainstem were identified as the structures requiring coverage by a helmet. No papers were identified that directly defined the margins of these structures to anatomical landmarks, nor how these could be related to helmet coverage. CONCLUSIONS: We recommend relating the margins of the brain to three identifiable anatomical landmarks (nasion, external auditory meatus and superior nuchal line), which can in turn be related to the coverage provided by the helmet. Early assessments using an anatomical mannequin indicate that the current helmet covers the majority of the brain and brainstem from projectiles with a horizontal trajectory but not from ones that originate from the ground. Protection from projectiles with ground-originating trajectories is reduced by helmets with increased stand-off from the skin. Future helmet coverage assessments should use a finite element numerical modelling approach with representative material properties assigned to intracranial anatomical structures to enable differences in projectile trajectory and helmet coverage to be objectively compared.


Asunto(s)
Traumatismos por Explosión/prevención & control , Traumatismos Penetrantes de la Cabeza/prevención & control , Dispositivos de Protección de la Cabeza , Traumatismos Ocupacionales/prevención & control , Diseño de Equipo , Explosiones , Humanos , Personal Militar , Reino Unido
8.
J R Nav Med Serv ; 100(2): 161-5, 2014.
Artículo en Inglés | MEDLINE | ID: mdl-25335311

RESUMEN

We present eleven years of prospectively-gathered data defining the full spectrum of the United Kingdom's (UK) Naval Service (Royal Navy and Royal Marines) casualties, and characterise the injury patterns, recovery and residual functional burden from the conflicts of the last decade. The UK Military Trauma Registry was searched for all Naval Service personnel injured between March 2003 and April 2013. These records were then cross-referenced with the records of the Naval Service Medical Board of Survey (NSMBOS), which evaluates injured Naval Service personnel for medical discharge, continued service in a reduced capacity or Return to Full Duty (RTD). Population at risk data was calculated from service records. There were 277 casualties in the study period: 63 (23%) of these were fatalities. Of the 214 survivors, 63 or 29% (23% of total) were medically discharged; 24 or 11% (9% of total) were placed in a reduced fitness category with medical restrictions placed on their continued military service. A total of 127 individuals (46% of the total and 59% of survivors) RTD without any restriction. The greatest number of casualties was sustained in 2007. There was a 3% casualty risk per year of operational service for Naval Service personnel. The most common reason cited by Naval Service Medical Board of Survey (NSMBOS) for medical downgrading or discharge was injury to the lower limb, with upper limb trauma the next most frequent. This study characterises the spectrum of injuries sustained by the Naval Service during recent conflicts with a very high rate of follow-up. Extremity injuries pose the biggest challenge to reconstructive and rehabilitative services striving to maximise the functional outcomes of injured service personnel.


Asunto(s)
Campaña Afgana 2001- , Costo de Enfermedad , Guerra de Irak 2003-2011 , Personal Militar/estadística & datos numéricos , Heridas y Lesiones/epidemiología , Extremidades/lesiones , Humanos , Puntaje de Gravedad del Traumatismo , Reino Unido/epidemiología , Heridas y Lesiones/mortalidad
9.
Injury ; 45(7): 1111-6, 2014 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-24485549

RESUMEN

INTRODUCTION: Recent conflicts have been characterised by the use of improvised explosive devices causing devastating injuries, including heavily contaminated wounds requiring meticulous surgical debridement. After being rendered surgical clean, these wounds are dressed and the patient transferred back to the UK for on-going treatment. A dressing that would prevent wounds from becoming colonised during transit would be desirable. The aim of this study was to establish whether using nanocrystalline silver dressings, as an adjunct to the initial debridement, would positively affect wound microbiology and wound healing compared to standard plain gauze dressings. METHODS: Patients were prospectively randomised to receive either silver dressings, in a nanocrystalline preparation (Acticoat™), or standard of care dressings (plain gauze) following their initial debridement in the field hospital. On repatriation to the UK microbiological swabs were taken from the dressing and the wound, and an odour score recorded. Wounds were followed prospectively and time to wound healing was recorded. Additionally, patient demographic data were recorded, as well as the mechanism of injury and Injury Severity Score. RESULTS: 76 patients were recruited to the trial between February 2010 and February 2012. 39 received current dressings and 37 received the trial dressings. Eleven patients were not swabbed. There was no difference (p=0.1384, Fishers) in the primary outcome measure of wound colonisation between the treatment arm (14/33) and the control arm (20/32). Similarly time to wound healing was not statistically different (p=0.5009, Mann-Whitney). Wounds in the control group were scored as being significantly more malodorous (p=0.002, Mann-Whitney) than those in the treatment arm. CONCLUSIONS: This is the first randomised controlled trial to report results from an active theatre of war. Performing research under these conditions poses additional challenges to military clinicians. Meticulous debridement of wounds remains the critical determinant in wound healing and infection and this study did not demonstrate a benefit of nanocrystaline silver dressing in respect to preventing wound colonisation or promoting healing, these dressings do however seem to significantly reduce the unpleasant odour commonly associated with battlefield wounds.


Asunto(s)
Vendajes , Traumatismos por Explosión/terapia , Nanopartículas del Metal/uso terapéutico , Personal Militar , Compuestos de Plata/uso terapéutico , Traumatismos de los Tejidos Blandos/terapia , Heridas por Arma de Fuego/terapia , Administración Tópica , Adulto , Traumatismos por Explosión/microbiología , Traumatismos por Explosión/patología , Desbridamiento/métodos , Humanos , Masculino , Estudios Prospectivos , Traumatismos de los Tejidos Blandos/microbiología , Traumatismos de los Tejidos Blandos/patología , Factores de Tiempo , Transporte de Pacientes , Resultado del Tratamiento , Cicatrización de Heridas , Infección de Heridas/prevención & control , Heridas por Arma de Fuego/microbiología , Heridas por Arma de Fuego/patología
10.
J R Army Med Corps ; 160(3): 220-5, 2014 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-24109106

RESUMEN

INTRODUCTION: Neck injuries sustained by UK service personnel serving on current operations from explosively propelled fragments result in significant mortality and long-term morbidity. Many of these injuries could potentially have been prevented had the soldiers been wearing their issued neck collars at the time of injury. The aim of this research is to develop an accurate method of predicting the resultant damage to cervical neurovascular structures from explosively propelled fragments. CURRENT STATUS: A finite element numerical model has been developed based on an anatomically accurate, anthropometrically representative 3D mathematical mesh of cervical neurovascular structures. Currently, the model simulates the passage of a fragment simulating projectile through all anatomical components of the neck using material models based upon 20% ballistic gelatin on the simplification that all tissue types act like homogenous muscle. FUTURE RESEARCH: The material models used to define the properties of each element within the model will be sequentially replaced by ones specific to each individual tissue within an anatomical structure. However, the cumulative effect of so many additional variables will necessitate experimental validation against both animal models and post-mortem human subjects to improve the credibility of any predictions made by the model. We believe this approach will in the future have the potential to enable objective comparisons between the mitigative effects of different body armour systems to be made with resultant time and financial savings.


Asunto(s)
Traumatismos por Explosión/patología , Análisis de Elementos Finitos , Medicina Militar/instrumentación , Personal Militar , Traumatismos del Cuello/patología , Heridas Penetrantes/patología , Algoritmos , Traumatismos por Explosión/etiología , Traumatismos por Explosión/prevención & control , Humanos , Modelos Biológicos , Traumatismos del Cuello/etiología , Traumatismos del Cuello/prevención & control , Ropa de Protección , Reproducibilidad de los Resultados , Heridas Penetrantes/etiología , Heridas Penetrantes/prevención & control
11.
Transfus Med ; 24(3): 154-61, 2014 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-24372770

RESUMEN

OBJECTIVE: To document blood component usage in the UK medical treatment facility, Afghanistan, over a period of 4 years; and to examine the relationship with transfusion capability, injury pattern and survival. BACKGROUND: Haemostatic resuscitation is now firmly established in military medical practice, despite the challenges of providing such therapy in austere settings. MATERIALS AND METHODS: Retrospective study of blood component use in service personnel admitted for trauma. Data were extracted from the UK Joint Theatre Trauma Registry. RESULTS: A total of 2618 patients were identified. Survival increased from 76 to 84% despite no change in injury severity. The proportion of patients receiving blood components increased from 13 to 32% per annum; 417 casualties received massive transfusion (≥10 units of RCC), the proportion increasing from 40 to 62%. Use of all blood components increased significantly in severely injured casualties, to a median (IQR) of 16 (9-25) units of red cell concentrate (P = 0·006), 15 (8-24) of plasma (P = 0·002), 2 (0-5) of platelets (P < 0·001) and 1 (0-3) of cryoprecipitate (P < 0·001). Cryoprecipitate (P = 0·009) and platelet use (P = 0·005) also increased in moderately injured casualties. CONCLUSIONS: The number of blood components transfused to individual combat casualties increased during the 4-year period, despite no change in injury severity or injury pattern. Survival also increased. Combat casualties requiring massive transfusion have a significantly higher chance of survival than civilian patients. Survival is the product of the entire system of care. However, we propose that the changes in military transfusion practice and capability have contributed to increased combat trauma survival.


Asunto(s)
Campaña Afgana 2001- , Transfusión Sanguínea/métodos , Medicina Militar/métodos , Medicina Militar/organización & administración , Sistema de Registros , Afganistán , Femenino , Humanos , Masculino , Estudios Retrospectivos , Reino Unido
12.
Anaesthesia ; 68(8): 846-50, 2013 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-23724784

RESUMEN

We assessed acidosis, coagulopathy and hypothermia, before and after surgery in 51 combat troops operated on for severe blast injury. Patients were transfused a median (IQR [range]) of 27 (17-38 [5-84]) units of red cell concentrate, 27 (16-38 [4-83]) units of plasma, 2.0 (0.5-3.5 [0-13.0]) units of cryoprecipitate and 4 (2-6 [0-17]) pools of platelets. The pH, base excess, prothrombin time and temperature increased: from 7.19 (7.10-7.29 [6.50-7.49]) to 7.45 (7.40-7.51 [7.15-7.62]); from -9.0 (-13.5 to -4.5 [-28 to -2]) mmol.l⁻¹ to 4.5 (1.0-8.0 [-7 to +11]) mmol.l⁻¹; from 18 (15-21 [9-24]) s to 14 (11-18 [9-21]) s; and from 36.1 (35.1-37.1 [33.0-38.1]) °C to 37.4 (37.0-37.9 [36.0-38.0]) °C, respectively. Contemporary intra-operative resuscitation strategies can normalise the physiological derangements caused by haemorrhagic shock.


Asunto(s)
Acidosis/terapia , Traumatismos por Explosión/terapia , Trastornos de la Coagulación Sanguínea/terapia , Hipotermia/terapia , Choque Hemorrágico/terapia , Acidosis/etiología , Adolescente , Adulto , Campaña Afgana 2001- , Ambulancias Aéreas , Amputación Quirúrgica , Traumatismos por Explosión/complicaciones , Trastornos de la Coagulación Sanguínea/etiología , Temperatura Corporal , Transfusión de Eritrocitos , Humanos , Concentración de Iones de Hidrógeno , Hipotermia/etiología , Periodo Intraoperatorio , Traumatismos de la Pierna/terapia , Masculino , Persona de Mediana Edad , Plasma , Transfusión de Plaquetas , Tiempo de Protrombina , Resucitación , Estudios Retrospectivos , Choque Hemorrágico/complicaciones , Resultado del Tratamiento , Adulto Joven
13.
Bone Joint J ; 95-B(2): 224-9, 2013 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-23365033

RESUMEN

This is a case series of prospectively gathered data characterising the injuries, surgical treatment and outcomes of consecutive British service personnel who underwent a unilateral lower limb amputation following combat injury. Patients with primary, unilateral loss of the lower limb sustained between March 2004 and March 2010 were identified from the United Kingdom Military Trauma Registry. Patients were asked to complete a Short-Form (SF)-36 questionnaire. A total of 48 patients were identified: 21 had a trans-tibial amputation, nine had a knee disarticulation and 18 had an amputation at the trans-femoral level. The median New Injury Severity Score was 24 (mean 27.4 (9 to 75)) and the median number of procedures per residual limb was 4 (mean 5 (2 to 11)). Minimum two-year SF-36 scores were completed by 39 patients (81%) at a mean follow-up of 40 months (25 to 75). The physical component of the SF-36 varied significantly between different levels of amputation (p = 0.01). Mental component scores did not vary between amputation levels (p = 0.114). Pain (p = 0.332), use of prosthesis (p = 0.503), rate of re-admission (p = 0.228) and mobility (p = 0.087) did not vary between amputation levels. These findings illustrate the significant impact of these injuries and the considerable surgical burden associated with their treatment. Quality of life is improved with a longer residual limb, and these results support surgical attempts to maximise residual limb length.


Asunto(s)
Amputación Quirúrgica/estadística & datos numéricos , Traumatismos de la Pierna/cirugía , Extremidad Inferior/cirugía , Personal Militar , Adulto , Femenino , Estudios de Seguimiento , Humanos , Puntaje de Gravedad del Traumatismo , Masculino , Estudios Prospectivos , Calidad de Vida , Encuestas y Cuestionarios , Resultado del Tratamiento , Reino Unido
14.
Bone Joint J ; 95-B(1): 101-5, 2013 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-23307681

RESUMEN

The aim of this study was to report the pattern of severe open diaphyseal tibial fractures sustained by military personnel, and their orthopaedic-plastic surgical management.The United Kingdom Military Trauma Registry was searched for all such fractures sustained between 2006 and 2010. Data were gathered on demographics, injury, management and preliminary outcome, with 49 patients with 57 severe open tibial fractures identified for in-depth study. The median total number of orthopaedic and plastic surgical procedures per limb was three (2 to 8). Follow-up for 12 months was complete in 52 tibiae (91%), and half the fractures (n = 26) either had united or in the opinion of the treating surgeon were progressing towards union. The relationship between healing without further intervention was examined for multiple variables. Neither the New Injury Severity Score, the method of internal fixation, the requirement for vascularised soft-tissue cover nor the degree of bone loss was associated with poor bony healing. Infection occurred in 12 of 52 tibiae (23%) and was associated with poor bony healing (p = 0.008). This series characterises the complex orthopaedic-plastic surgical management of severe open tibial fractures sustained in combat and defines the importance of aggressive prevention of infection.


Asunto(s)
Fijación Interna de Fracturas , Fracturas Abiertas/cirugía , Procedimientos de Cirugía Plástica , Fracturas de la Tibia/cirugía , Guerra , Adulto , Estudios de Seguimiento , Fijación Interna de Fracturas/métodos , Fijación Interna de Fracturas/estadística & datos numéricos , Fracturas Abiertas/etiología , Humanos , Puntaje de Gravedad del Traumatismo , Procedimientos de Cirugía Plástica/métodos , Procedimientos de Cirugía Plástica/estadística & datos numéricos , Sistema de Registros , Infección de la Herida Quirúrgica/epidemiología , Fracturas de la Tibia/etiología , Resultado del Tratamiento , Reino Unido , Cicatrización de Heridas
15.
Injury ; 44(1): 36-9, 2013 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-22204772

RESUMEN

BACKGROUND: Rotational thromboelastometry (ROTEM(®)) relies on citrated blood samples, which are regarded as biologically stable for up to 4 h after venepuncture. However, this recommendation is based on data from normal volunteers. The aim of this study was to evaluate possible temporal changes in the coagulability of blood samples from coagulopathic trauma patients. PATIENTS AND METHODS: This is a prospective series of 10 coagulopathic (maximum clot firmness, MCF<40 mm) trauma patients. ROTEM(®) EXTEM (tissue factor activated) and FIBTEM (tissue factor activated, cytochalasin D inhibited) analyses were performed on samples obtained on admission, and after approximately 60 min of storage in an incubator, at 37°C. RESULTS: There were statistically significant differences between the median EXTEM MCF (22 mm vs 54 mm, p<0.001) and α angle (30.5 vs 59.5°, p=0.004) of the analyses performed immediately after sampling, and 51 min (median) subsequently, but not coagulation time (CT, p=0.133), clot formation time (p=0.0625) or maximum lysis (ML, p=0.154). There were also no differences in median FIBTEM MCF (p=1.00) or CT (p=0.877) between the immediate and delayed analyses. CONCLUSIONS: Repeated ROTEM(®) EXTEM analysis of citrated samples from coagulopathic trauma patients shows a spontaneous improvement in coagulability with time. The absence of parallel changes on FIBTEM analysis suggests that this effect may be due to a change in platelet function.


Asunto(s)
Traumatismos por Explosión/sangre , Trastornos de la Coagulación Sanguínea/sangre , Pruebas de Coagulación Sanguínea/métodos , Tromboelastografía , Heridas Penetrantes/sangre , Adulto , Campaña Afgana 2001- , Coagulación Sanguínea , Trastornos de la Coagulación Sanguínea/terapia , Femenino , Hemostasis , Humanos , Masculino , Proyectos Piloto , Recuento de Plaquetas , Sistemas de Atención de Punto , Valor Predictivo de las Pruebas , Estudios Prospectivos , Factores de Tiempo
16.
Br J Oral Maxillofac Surg ; 51(1): 47-51, 2013 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-22459006

RESUMEN

The number of neck injuries has increased during the war in Afghanistan, and they have become an appreciable source of mortality and long-term morbidity for UK servicemen. A three-dimensional numerical model of the neck is necessary to allow simulation of penetrating injury from explosive fragments so that the design of body armour can be optimal, and a framework is required to validate and describe the individual components of this program. An interdisciplinary consensus group consisting of military maxillofacial surgeons, and biomedical, physical, and material scientists was convened to generate the components of the framework, and as a result it incorporates the following components: analysis of deaths and long-term morbidity, assessment of critical cervical structures for incorporation into the model, characterisation of explosive fragments, evaluation of the material of which the body armour is made, and mapping of the entry sites of fragments. The resulting numerical model will simulate the wound tract produced by fragments of differing masses and velocities, and illustrate the effects of temporary cavities on cervical neurovascular structures. Using this framework, a new shirt to be worn under body armour that incorporates ballistic cervical protection has been developed for use in Afghanistan. New designs of the collar validated by human factors and assessment of coverage are currently being incorporated into early versions of the numerical model. The aim of this paper is to describe this developmental framework and provide an update on the current progress of its individual components.


Asunto(s)
Traumatismos por Explosión/fisiopatología , Diseño de Equipo/métodos , Personal Militar , Traumatismos del Cuello/prevención & control , Ropa de Protección , Heridas Penetrantes/prevención & control , Simulación por Computador , Diseño Asistido por Computadora , Humanos , Traumatismos del Cuello/clasificación , Heridas Penetrantes/clasificación
17.
J Trauma Acute Care Surg ; 73(6 Suppl 5): S479-82, 2012 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-23192073

RESUMEN

BACKGROUND: The selective nonoperative management of ballistic abdominal injury remains contentious, particularly in the military setting. The exigencies of military practice have traditionally favored a more liberal approach to abdominal exploration. The driver for selective nonoperative management is the avoidance of morbidity incurred by nontherapeutic intervention. However, the incidence and complications of nontherapeutic laparotomy (NTL) in the military setting are not known. METHODS: All UK military patients undergoing a laparotomy following battlefield trauma were identified from the UK Joint Theatre Trauma Registry. Procedures were classed as therapeutic laparotomy (TL) or NTL. Demographics, admission physiology, injury pattern, and mortality were compared, and complications in the NTL group were determined by Joint Theatre Trauma Registry and case record review. RESULTS: Between March 2003 and March 2011, 130 (7.2%) of 1,813 combat wounded UK service personnel underwent a laparotomy. A total of 103 (79.2%) were considered TL, and 27 (20.8%) were NTL. There was no difference in demographic distribution or mechanism of injury. Patients undergoing TL were more likely to be hypotensive (systolic blood pressure, <90 mm Hg; p = 0.015) and have a reduced consciousness level (Glasgow Coma Scale [GCS] score ≤ 8; p = 0.006). There was a greater abdominal injury burden in the TL group (p < 0.001). There was no difference in severe extra-abdominal injury (Abbreviated Injury Scale [AIS] score ≥ 3), overall Injury Severity Score (ISS) and New ISS (NISS) scores, or mortality. Of the 27 patients who underwent NTL, 7 (25.9%) developed complications. CONCLUSION: During the past decade, trauma laparotomy has become a relatively uncommon procedure. The NTL rate is also relatively low. This finding could be explained by the fact that selective nonoperative management is used more widely in the military setting than previously thought or that very few military injuries are amenable to nonoperative management. NTL is associated with a significant risk of complications and should therefore be minimized but not at the expense of missing a life-threatening intra-abdominal injury. LEVEL OF EVIDENCE: Therapeutic study, level IV.


Asunto(s)
Traumatismos Abdominales/cirugía , Traumatismos por Explosión/cirugía , Laparotomía/métodos , Incidentes con Víctimas en Masa/estadística & datos numéricos , Guerra , Traumatismos Abdominales/epidemiología , Traumatismos Abdominales/etiología , Adulto , Campaña Afgana 2001- , Traumatismos por Explosión/complicaciones , Femenino , Humanos , Incidencia , Puntaje de Gravedad del Traumatismo , Guerra de Irak 2003-2011 , Laparotomía/estadística & datos numéricos , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias/epidemiología , Complicaciones Posoperatorias/fisiopatología , Sistema de Registros , Estudios Retrospectivos , Medición de Riesgo , Análisis de Supervivencia , Resultado del Tratamiento , Reino Unido , Adulto Joven
19.
J R Army Med Corps ; 158(2): 82-4, 2012 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-22860495

RESUMEN

Damage Control Resuscitation and Damage Control Surgery (DCR-DCS) is an approach to managing severely injured patients according to their physiological needs, in order to optimise outcome. Key to delivering DCR-DCS is effective communication between members of the clinical team and in particular between the surgeon and anaesthetist, in order to sequence and prioritise interventions. Although the requirement for effective communication is self-evident, the principles to achieving this can be forgotten and sub-optimal when unexpected problems arise at critical points during management of challenging cases. A system is described which builds on the 'World Health Organisation (WHO) safer surgery checklist' and formalises certain stages of communication in order to assure the effective passage of key points. We have identified 3 distinct phases: (i) The Command Huddle, once the patient has been assessed in the Emergency room; (ii) The Snap Brief, once the patient has arrived in the Operating Room but before the start of surgery; and (iii) The Sit-Reps, every 10 minutes for the entire theatre team to maintain situational awareness and allow effective anticipation and planning.


Asunto(s)
Comunicación , Medicina Militar/métodos , Grupo de Atención al Paciente , Heridas y Lesiones/cirugía , Concienciación , Humanos , Comunicación Interdisciplinaria , Resucitación , Reino Unido
20.
Ann R Coll Surg Engl ; 94(1): 52-7, 2012 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-22524930

RESUMEN

INTRODUCTION: International humanitarian law requires emergency medical support for both military personnel and civilians, including children. Here we present a detailed review of paediatric admissions with the pattern of injury and the resources they consume. METHODS: All paediatric admissions to the hospital at Camp Bastion between 1 January and 29 April 2011 were analysed prospectively. Data collected included time and date of admission, patient age and weight, mechanism of injury, extent of wounding, treatment, length of hospital stay and discharge destination. RESULTS: Eighty-five children (65 boys and 17 girls, median age: 8 years, median weight: 20 kg) were admitted. In 63% of cases the indication for admission was battle related trauma and in 31% non-battle trauma. Of the blast injuries, 51% were due to improvised explosive devices. Non-battle emergencies were mainly due to domestic burns (46%) and road traffic accidents (29%). The most affected anatomical area was the extremities (44% of injuries). Over 30% of patients had critical injuries. Operative intervention was required in 74% of cases. The median time to theatre for all patients was 52 minutes; 3 patients with critical injuries went straight to theatre in a median of 7 minutes. A blood transfusion was required in 27 patients; 6 patients needed a massive transfusion. Computed tomography was performed on 62% of all trauma admissions and 40% of patients went to the intensive care unit. The mean length of stay was 2 days (range: 1-26 days) and there were 7 deaths. CONCLUSIONS: Paediatric admissions make up a small but significant part of admissions to the hospital at Camp Bastion. The proportion of serious injuries is very high in comparison with admissions to a UK paediatric emergency department. The concentration of major injuries means that lessons learnt in terms of teamwork, the speed of transfer to theatre and massive transfusion protocols could be applied to UK paediatric practice.


Asunto(s)
Hospitalización/estadística & datos numéricos , Hospitales Militares/estadística & datos numéricos , Heridas y Lesiones/epidemiología , Adolescente , Campaña Afgana 2001- , Afganistán/epidemiología , Distribución por Edad , Traumatismos por Explosión/epidemiología , Traumatismos por Explosión/terapia , Transfusión Sanguínea/estadística & datos numéricos , Quemaduras/epidemiología , Quemaduras/terapia , Niño , Preescolar , Tratamiento de Urgencia/estadística & datos numéricos , Femenino , Recursos en Salud/estadística & datos numéricos , Humanos , Lactante , Masculino , Auditoría Médica , Heridas y Lesiones/terapia , Heridas por Arma de Fuego/epidemiología , Heridas por Arma de Fuego/terapia
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