[Usefulness of examining gonadotropin hormones and testosterone in men with abnormal semen]. / Przydatnosc badan hormonów gonadotropowych i testosteronu u mezczyan o nieprawidlowym nasieniu.

The aim of the study was to estimate the usefulness of some hormonal investigations in cases of males with abnormalities in semen analysis in the diagnosis of the male factor in the infertile couple. 107 males with the abnormalities in spermiogram underwent the analysis of the blood serum hormonal levels. Estimated was the level of FSH, LH, prolactin and testosterone. The control group consisted of 31 males with normospermia. The study group was divided according to terminology. In all four groups of infertility the mean values of FSH were significantly higher than in control group. There was no significant differences in LH levels between the groups. The mean values of prolactin level were not significantly higher in the cases of hypospermia than in normospermia group, but significantly higher in the other groups of infertility. The mean level of testosterone was significantly lower in all four groups of infertility in comparison with it's mean level in normospermia group. It was found that the FSH is the most discriminatory hormone in respect of infertility classification and therefore it's diagnostic value is the highest among the four hormones investigated.

[Detection and treatment of hyperprolactinemia in male infertility]. / Wykrywanaie i leczenie hiperprolaktynemii w czynniku meskim.

The role of prolactin in males has not been satisfactorily explained. It has been proved that hyperprolactinemia has a negative effect both on spermiogenesis and spermatogenesis. It is widely known that the secretion of the pituitary hormones is of a pulsating character and occurs in the diurnal rhythm. Therefore, in order to select a group of patients with hyperprolactinemia qualified for Bromocriptine treatment it was necessary to test them for prolactin. 3 morning tests were taken at 15 minute intervals. The selected male group was later treated with Bromocriptine, following the method of administration recommended by the producer. Next the level of prolactin in patients serum was again determined. It has been determined that a single prolactin test is sufficient to diagnose hyperprolactinemia. In most males 3 prolactin tests were always either pathologic or normal. Most of the selected hyperprolactinemia--affected males after Bromocriptine treatment displayed positive therapeutic effects. The level of prolactin has dropped considerably and the potency has increased. The improvement in the semen picture varied from patient to patient.

[Histologic evaluation of testis in men with azoospermia in light of hormonal determination]. / Ocena histologiczna jader u mzczyzn z azoospermia w swietle badan hormonalnych.

The causes of azoospermia may be of varied nature and are often difficult to determine. Generally, there are two morphological-clinical types of azoospermia. The first is due to the occlusion of the outgoing seminal tracts. The second is manifested by the lack of seminiferous epithelium, diagnosed on microscopic examination as acquired or primary Sertoli Cell Syndrome. In order to establish the distinctive features of both types of azoospermia a group of azoospermia--affected males underwent a morphological-biochemical analysis. 38 patients with azoospermia had surgical biopsy of testes, and hormonal determination of the pituitary gland and testis i.e. prolactin, LH, FSH, testosterone. Microscopic examination helped to select a group with Sertoli Cell Syndrome. This group exhibited statistically significant thickening of the basement membrane and FSH--levels markedly elevated in relation to both the norm and other azoospermia--affected patients. The above findings are in conformity with the recent research on the increase of FSH--level in azoospermia, and particular in Sertoli Cell Syndrome. They also confirm the validity of carrying out biopsies in the aforementioned clinical group because of the possibility of selecting patients for anastomosis of spermatic ducts or spermocele implantation. The fact that Sertoli Cell Syndrome is accompanied by a high FSH level could be utilized for the screening of patients for testes biopsy.

[Rapid preliminary diagnosis of anaerobic bacterial infections. I. Natural fluorescence of pus, purulent fluids and dressing under UV radiation]. / Szybka, wstepna diagnostyka zakazen bakteriami beztlenowymi. I. Fluorescencja naturalna ropy, plynów ropnych i opatrunków pod wplywem promieniowania UV.

For evaluation of usefulness of natural fluorescence of clinical materials in UV radiation as rapid diagnostic method of infections with anaerobes, 405 samples of pus, bloody-purulent fluids, blood, wound secretions, dressings and other materials were investigated. Occurrence of red-brick UV fluorescence of clinical materials was compared with results of culture aimed at isolation of non-sporeforming anaerobes from "B. melaninogenicus group (P. melaninogenica, P. intermedia and P. saccharolytics). Significant correlation red-brick fluorescence of clinical materials resulting from UV irradiation with presence in these materials of anaerobes such as P. melaninogenica, P. intermedia and P. asaccharolytics was detected. Investigation of clinical materials with application of fluorescence in UV radiation lasts only 1-2 minutes and together with preparation and microscopical inspection which is Gram-stained--only 15-20 min. Positive results of this test may constitute a basis for rapid, preliminary identification of the etiologic factor and for direction of chemotherapy in the early period of infection.

Cartilaginous teratoma of the ovary.

A case of ovarian teratoma of unique differentiation in a woman of 35 years is reported. Within the histologic structure of the tumor there is predominated cartilaginous tissue with signs of nuclear atypia. The microscopic appearance of the tumor resembled structures seen in chondroblastoma embryonale or even chondrosarcoma. Despite of cellular atypica there are no symptoms of malignant clinical course.

[Histological, morphometric and topochemical analysis of placentas from pregnancies with EPH Gestosis (author's transl)]. / Histologische, morphometrische und topochemische Analyse der Plazenten von Schwangerschaften bei EPH-Gestose.

The authors' studies have shown three pathological phenomena to be predominant in placentas of women with EPH gestosis: disappearance of acid mucosubstance from wall of spiral arteries, reduction of ATPase, 5-Nase, and aP activities on apical and basal surfaces of terminal villi, and numerical increase as well as de-differentiation of trophoblastic nodes. Vulnerability of vascular walls to the action of vasodepressive factors is aggravated, according to the authors, in cases of complicated gestosis in which aMPS levels in the muscular membranes of spiral arteries are inadequate.