RESUMEN
Creating a map of actors and their leanings is important for policy makers and stakeholders in the European Commission's 'Better Regulation Agenda'. We explore publicly available information about the European lobby organizations from the Transparency Register, and from the open public consultations in the area of Banking and Finance. We consider three complementary types of information about lobbying organizations: (i) their formal categorization in the Transparency Register, (ii) their responses to the public consultations, and (iii) their self-declared goals and activities. We consider responses to the consultations as the most relevant indicator of the actual leaning of an individual lobbyist. We partition and cluster the organizations according to their demonstrated interests and the similarities among their responses. Thus each lobby organization is assigned a profile which shows its prevailing interest in consultations' topics, similar organizations in interests and responses, and a prototypical question and answer. We combine methods from network analysis, clustering, and text mining to obtain these profiles. Due to the non-homogeneous consultations, we find that it is crucial to first construct a response network based on interests in consultations topics, and only then proceed with more detailed analysis of the actual answers to consultations. The results provide a first step in the understanding of how lobby organizations engage in the policy making process.
RESUMEN
BACKGROUND: Increased life expectancy of human immunodeficiency virus (HIV)-infected patients appears to be coupled with increased incidence of cardiovascular disease (CVD). AIM: The aim of our study was to determine the presence of early atherosclerosis among Slovenian HIV-infected patients below the age of 55 years. METHODS: A total of 86 HIV-infected male patients below the age of 55 years participated in our study. Ankle-brachial index (ABI) was measured using a handheld Doppler ultrasonic probe and a blood pressure cuff. Carotid intima-media thickness (CIMT) was assessed by the B-mode high-resolution ultrasound technique. Low ABI, CIMT > 0.8 mm or presence of carotid plaques were considered markers of early atherosclerosis. RESULTS: Average CIMT was lowest among treatment-naïve patients (0.65 mm); 10 (38.4 %) had CIMT > 0.8 mm, and carotid plaques were detected in 1 (3.8 %). Average CIMT among treated patients was 0.71 mm; 30 (50.0 %) had CIMT > 0.8 mm, and plaques were detected in 11 (18.3 %). Low ABI (≤ 0.90) was found in five patients (5.8 %) without symptoms of peripheral artery disease; two were treatment-naïve, and three received antiretroviral therapy. Early atherosclerosis was found in 43 (50.0 %) patients; 10 (38.4 %) were in treatment-naïve and 33 (55.0 %) in the treated group. CONCLUSIONS: Increased prevalence of early atherosclerosis among Slovenian HIV-infected patients below the age of 55 years has been demonstrated. Screening for early atherosclerosis should be implemented in the evaluation of young HIV-infected patients because a more aggressive treatment approach, aimed to delay the progression of atherosclerosis, may be warranted especially when carotid plaques are detected. We have shown that although ABI contributes to CVD risk assessment, CIMT assessment remains the more sensitive method.
