Riboflavin-catalyzed templated reaction to translate nucleic acid cues into signals of rhodamine derivatives.

We report a templated reaction for the facile translation of nucleic acid cues into signals of universal rhodamine derivatives based on the riboflavin-catalyzed oxidation of dihydrorhodamine compounds. The rhodamine-signaling operation enabled us to design a highly sequence-selective fluorescent sensor that can detect as little as 500 pM of the target nucleic acid in 90 min or to present a rhodamine antibody that can be further applied to immunoassays.

Electrochemical, Photophysical and Theoretical Studies of Novel Zinc Phthalocyanines.

In this research, we successfully synthesized three novel zinc phthalocyanines and applied for electrochemical and photo physical properties. These phthalocyanines are naphthoxy derivatives with methyl, benzyl and butyl-benzyl, with halo substitution (PCME, PCBN and PCBBN) and poses very good solubility in all industrial solvents. To check the preliminary results of LCD green color filter properties of these molecules, we taken the UV-Visible absorption and transmittance studies in Propylene glycol monomethyl ether acetate and achieved around 90% of transmittance in the region of 400-550 nm. Further understand the solubility of our phthalocyanines, we checked the aggregation property in PGMEA and we observed no any aggregation. All compounds showed very nice electro chemical properties with nice oxidation and reduction peaks. These phthalocyanines are fit for LCD color filter applications. Finally to get insights of the electronic and UV-Visible properties of the new dyes, the DFT calculations were performed.