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Curr Opin Virol ; 36: 25-31, 2019 06.
Artículo en Inglés | MEDLINE | ID: mdl-30889472

RESUMEN

In the last few decades, the isolation of amoebae-infecting giant viruses has challenged established principles related to the definition of virus, their evolution, and their particle structures represented by a variety of shapes and sizes. Tupanviruses are one of the most recently described amoebae-infecting viruses and exhibit a peculiar morphology with a cylindrical tail attached to the capsid. Proteomic analysis of purified viral particles revealed that virions are composed of over one hundred proteins with different functions. The putative origin of these proteins had not yet been investigated. Here, we provide evidences for multiple origins of the proteins present in tupanvirus particles, wherein 20% originate from members of the archaea, bacteria and eukarya.


Asunto(s)
Virus Gigantes/química , Virus Gigantes/genética , Proteoma , Proteínas Virales/genética , Virión/química , Amoeba/virología , Archaea/genética , Bacterias/genética , Eucariontes/genética , Proteómica , Proteínas Virales/química , Virión/genética
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