Spindle Cell Hemangioma of Lower Lip: The Fourth Case Report with Review of Literature.

Background: Spindle cell hemangioma previously known as spindle cell hemangioendothelioma is a benign vascular tumour with rare presentation in head and neck. Presentation in lip is even rarer with three cases reported previously. Method: This report describes a case of spindle cell hemangioma presented as an asymptomatic growth on lower lip of a 32-year-old male. Clinicopathological characterization of this case along with previously reported 15 cases of spindle cell hemangioma of head and neck were conducted. Result: Microscopic evaluation shows a well-circumscribed vascular neoplasm of spindled and epithelioid endothelial cells. Large ectatic thin-walled vascular spaces were seen engorged with RBCs. The neoplasm was CD31 positive. Slight predilection for female gender and young age were observed. Minimal possibility of recurrence was also observed. Conclusion: Spindle cell hemangioma needs to be considered in the differential diagnosis of vascular tumours of head and neck to avoid misdiagnosis of aggressive vascular neoplasms.

Haemangiopericytoma/Solitary Fibrous Tumour of Mandible: An Uncommonness in the Oral Cavity.

Among the bewildering variety of neoplasms occurring in the head and neck region, few are unique to the oral cavity which are quite challenging to diagnose. Due to the rarity of these tumours, it is the practicing oral pathologists' accountability to confirm some of these neoplasms with or without special investigative modalities to rule out the differential diagnosis histopathologically. One in the group of such tumour prevails haemangiopericytoma aka. solitary fibrous tumour (HPC/SFT). The management of these tumours is purely histopathologically driven, since the surgical procedure is dependent on the histological diagnosis. This neoplasm is histologically very difficult to confirm as benign or malignant without the use of immunohistochemical markers. We report such a rare case of a 54-year-old female patient, histopathologically confirmed diagnosis of HPC/SFT with CD34 positivity for documentation in the literature.

Comparison between N-butyl cyanoacrylate tissue adhesive and Ethilon nylon sutures in extraoral maxillofacial incisions: A randomized prospective study.

OBJECTIVES: Wound closure is a part of any surgical procedure. Wound care and healing process are concepts, which are usually reliant upon sutures. The suture and non-suture repair of the tissues has been a major concern to surgeons for over four thousand years. The objective of this study is to compare the rates of infection, wound dehiscence, necrosis and time required by N-butyl cyanoacrylate tissue adhesive and nylon sutures in extraoral maxillofacial wound closer. MATERIALS AND METHODS: 24 patients requiring external wound closing were included in this study. Patients were divided in two groups, in one group wound closer was done by N-butyl cyanoacrylate tissue adhesive and by conventional nylon suture in the other group. The software STATA® of StataCorp was used in statistical analysis if this study. RESULTS: Wound infection, dehiscence, necrosis of tissue edges, time taken for closure was much less in case of tissue adhesive than conventional sutures. CONCLUSION: Advantages of tissue adhesives over conventional wound closure techniques include easy to use, excellent bacteriostatic property, decreased repair time, elimination of recall visits and comparable short and long-term cosmetic outcome. Though tissue adhesives have many advantages over conventional wound closure techniques, they can be used as an alternative to sutures only in superficial small and tension free skin incisions or lacerations.

Filariasis in Mandible and Maxilla: A Rare Entity-First Report of a Case.

Wuchereria bancrofti, Brugia malayi, and Brugia timori, categorized as nematodes, are responsible for causing lymphatic filariasis. Even though it can affect individuals of all age groups and both genders, it predominantly affects people of low socioeconomic strata. The filarial worms dwell in the subcutaneous tissues and lymphatics of human hosts. In India, W bancrofti is the primary nematode to cause filariasis, which is transmitted through the bite of blood-sucking infected female anopheles mosquitoes. Lymphangitis, leading to elephantiasis of the legs, arms, scrotum, and breast, is the most salient clinical feature of lymphatic filariasis. The presence of filarial worms in the oral and perioral soft tissues is uncommon; moreover, the presence of filarial worms in a centrally occurring bony lesion is highly unusual and has not yet been reported. We report a case of a central giant cell granuloma due to filariasis that was diagnosed after biopsy of innocuous radiolucent bony lesions of the maxilla and mandible.

Management of Midline Facial Clefts.

Median or midline facial clefts are rare anomalies of developmental origin, etiology of whose occurrence is still unknown precisely. The most basic presentation of midline facial clefts is in the form of a Median cleft lip which is defined as any congenital vertical cleft through the centre of the upper lip. First described by Bechard in 1823, it is the most common amongst all atypical clefts reported. The incidence is about 1:10,00,000 births. This may occur as a sporadic event or as a part of an inherited sequence of anomalies. It arises embryologically from incomplete fusion of the medial nasal prominences. The authors present a series of eight cases with varying degrees of midline facial clefts. This review article aims to give a broad idea on the various classifications used for further understanding of midline facial clefts and a brief idea about the various surgical management techniques used in the repair of these facial clefts.

Primary diffuse large B-cell lymphoma in the anterior hard palate: A rare case report with review of literature.

Diffuse large B-cell lymphomas (DLBCLs) are defined as neoplasms of large transformed B cells, i.e. with nuclear diameter more than twice that of a normal lymphocyte. These account for 30-40% of all adult non-Hodgkin's lymphomas (NHL). Intraoral lymphomas are relatively rare and often difficult to diagnose in clinical settings. In this case report, we describe a case of primary DLBCL affecting the anterior part of the hard palate of an elderly male patient. DLBCL of anterior part of hard palate is yet to be reported in the English literature, even though DLBCL cases involving the posterior palate have been recorded, thus making the present case to be first of its kind. Emphasis has also been given on the subclassification, differential diagnosis and prognostic antibody factors determining the outcome of DLBCL.

Giant pindborg tumor (calcifying epithelial odontogenic tumor): an unusual case report with radiologic-pathologic correlation.

Odontogenic tumors develop in the jaws from odontogenic tissues such as enamel organ, Hertwig epithelial root sheath, dental lamina, and so on. A variety of tumors unique to the maxilla and mandible are therefore seen. Calcifying epithelial odontogenic tumor (CEOT) is a rare, aggressive, benign odontogenic tumor of epithelial origin accounting for only about 1% of all odontogenic tumors. It is eponymously called "Pindborg tumor", as it was first described by Pindborg in 1955. The origin of this locally invasive tumor remains unknown. It is thought to arise from stratum intermedium. It commonly affects the posterior mandible manifesting as a slow-growing asymptomatic swelling often associated with an impacted tooth. We report a case of CEOT, for which, owing to its huge size we have proposed the term "giant" Pindborg tumor (CEOT). This is probably the largest case of this tumor reported so far in the English literature. The present case also has the classic yet rare "driven snow" appearance of the tumor on radiographs.