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Jpn J Infect Dis ; 69(2): 151-3, 2016.
Artículo en Inglés | MEDLINE | ID: mdl-26166501

RESUMEN

A 53-year-old Japanese woman who was working as a volunteer in the Commonwealth of Dominica in the Caribbean islands presented with a high-grade fever and severe incapacitating generalized arthralgia. The Asian genotype of the chikungunya virus was confirmed using reverse transcription-PCR and serology, based on the presence of a specific neutralization titer and immunoglobulin M antibodies. She was diagnosed with post-chikungunya chronic arthritis based on persistence of her polyarthritis for 3 months and the presence of rheumatoid factor, immunoglobulin G-rheumatoid factor, and matrix metalloproteinase-3. Chikungunya virus should be considered as a causative pathogen in travelers returning from Caribbean islands. Clinicians should consider chikungunya fever in the differential diagnosis of patients who complain of chronic arthritis and have a history of travel to an endemic area.


Asunto(s)
Fiebre Chikungunya/diagnóstico , Fiebre Chikungunya/patología , Viaje , Animales , Anticuerpos Neutralizantes/sangre , Anticuerpos Antivirales/sangre , Dominica , Femenino , Humanos , Inmunoglobulina M/sangre , Japón , Persona de Mediana Edad , Reacción en Cadena de la Polimerasa , Pruebas Serológicas
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