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1.
Comput Biol Med ; 179: 108903, 2024 Jul 25.
Artículo en Inglés | MEDLINE | ID: mdl-39059211

RESUMEN

Exposure to ambient ultraviolet radiation is associated with various ocular pathologies. Estimating the irradiance received by the eyes is therefore essential from a preventive perspective and to study the relationship between light exposure and eye diseases. However, measuring ambient irradiance on the ocular surface is challenging. Current methods are either approximations or rely on simplified setups. Additionally, factors like head rotation further complicate measurements for prolonged exposures. This study proposes a novel numerical approach to address this issue by developing an analytical model for calculating irradiance received by the eye and surrounding ocular area. The model takes into account local ambient irradiance, sun position, and head orientation. It offers a versatile and cost-effective means of calculating ocular irradiance, adaptable to diverse scenarios, and serves both as a predictive tool and as a way to compute correction factors, such as the fraction of diffuse irradiance received by the eyes. Furthermore, it can be tailored for prolonged durations, facilitating the calculation of radiant dose obtained during extended exposures.

2.
Comput Biol Med ; 171: 108119, 2024 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-38367446

RESUMEN

Various skin and ocular pathologies can result from overexposure to ultraviolet radiation and blue light. Assessing the potential harm of exposure to these light sources requires quantifying the energy received to specific target tissue. Despite a well-established understanding of the light-disease relationship, the quantification of received energy in diverse lighting scenarios proves challenging due to the multitude of light sources and continuous variation in the orientation of receiving tissues (skin and eyes). This complexity makes the determination of health hazards associated with specific lighting conditions difficult. In this study, we present a solution to this challenge using a numerical approach. Through the implementation of algorithms applied to 3D geometries, we created and validated a numerical model that simulates skin and ocular exposure to both natural and artificial light sources. The resulting numerical model is a computational framework in which customizable exposure scenarios can be implemented. The ability to adapt simulations to different configurations for study makes this model a potential investigative method in human health research.


Asunto(s)
Piel , Rayos Ultravioleta , Humanos , Ojo
3.
Front Public Health ; 10: 900979, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35875046

RESUMEN

Exposure to ultraviolet light is associated with several ocular pathologies. Understanding exposure levels and factors is therefore important from a medical and prevention perspective. A review of the current literature on ocular exposure to ultraviolet light is conducted in this study. It has been shown that ambient irradiance is not a good indicator of effective exposure and current tools for estimating dermal exposure have limitations for the ocular region. To address this, three methods have been developed: the use of anthropomorphic manikins, measurements through wearable sensors and numerical simulations. The specific objective, limitations, and results obtained for the three different methods are discussed.


Asunto(s)
Ojo , Rayos Ultravioleta , Humanos , Maniquíes , Modelos Teóricos
4.
Comput Biol Med ; 141: 105135, 2022 02.
Artículo en Inglés | MEDLINE | ID: mdl-34959113

RESUMEN

The role of eyelashes in ocular radiation protection has been hypothesized for some time. There is however no quantitative knowledge of the shading they provide. The ocular protection provided by eyelashes is investigated in this study. A numerical model able to simulate an arbitrary source of light to illuminate a 3-dimensional head model with realistic details was used for this purpose. The eyelashes' filtering effect was studied for various light incidence angles, diameter and density of cilia. Using average values provided by literature to define their characteristics, we found that eyelashes reduce ultraviolet light received by the cornea of about 12-14%, with maximum values of 24%. These results suggest that the eyelashes can be an important element of the human eye protection system and their role should be further investigated.


Asunto(s)
Pestañas , Cilios , Ojo , Humanos , Rayos Ultravioleta/efectos adversos
5.
Photochem Photobiol ; 94(6): 1289-1296, 2018 11.
Artículo en Inglés | MEDLINE | ID: mdl-29878409

RESUMEN

Shade is an important means of protection against harmful effects of sun ultraviolet (UV) exposure, but not all shades are identically protective. UV rays scattered by the atmosphere and surroundings can reach the skin indirectly. To evaluate the relative contribution of the direct, diffuse, and reflected radiation in UV protection provided by different sizes of shade structure, we used SimUVEx v2, a numeric tool based on 3D graphic techniques and ambient ground UV irradiance. The relative UV exposure reduction was expressed by the predictive protection factor (PPF). Shade structures were found to predominantly reduce exposure from direct radiation (from 97.1% to 99.9% for the upper body areas such as the head and the neck), with greater protection from larger shade structures and structures closer above the subject. Legs were the least protected anatomical zone from any shade structure above the subject with PPF ranging from 18.5% to 68.1%. Throughout the day, except for lower solar zenith angles (SZA), small and high shade structures provide the lowest protection (between 20% and 50%), while small and low shade structure show PPF between 35% and 65% and large and high shade structures reach PPF higher than 60%.


Asunto(s)
Modelos Estadísticos , Dosis de Radiación , Piel/efectos de la radiación , Luz Solar/efectos adversos , Rayos Ultravioleta/efectos adversos , Brazo/efectos de la radiación , Simulación por Computador , Cabeza/efectos de la radiación , Humanos , Pierna/efectos de la radiación , Masculino , Maniquíes , Radiometría/estadística & datos numéricos , Dispersión de Radiación , Protectores Solares/análisis , Torso/efectos de la radiación
6.
Photodermatol Photoimmunol Photomed ; 34(5): 330-337, 2018 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-29682802

RESUMEN

BACKGROUND/PURPOSE: Solar ultraviolet radiation (UVR) doses received by individuals are highly influenced by behavioural and environmental factors. This study aimed at quantifying hats' sun protection effectiveness in various exposure conditions, by predicting UVR exposure doses and their anatomical distributions. METHODS: A well-defined 3-dimensional head morphology and 4 hat styles (a cap, a helmet, a middle- and a wide-brimmed hat) were added to a previously published model. Midday (12:00-14:00) and daily (08:00-17:00) seasonal UVR doses were estimated at various facial skin zones, with and without hat wear, accounting for each UVR component. Protection effectiveness was calculated by the relative reduction in predicted UVR dose, expressed as a predictive protection factor (PPF). RESULTS: The unprotected entire face received 2.5 times higher UVR doses during a summer midday compared to a winter midday (3.3 vs 1.3 standard erythema dose [SED]) with highest doses received at the nose (6.1 SED). During a cloudless summer day, the lowest mean UVR dose is received by the entire face protected by a wide-brimmed hat (1.7 SED). No hat reached 100% protection at any facial skin zone (PPFmax : 76%). Hats' sun protection effectiveness varied highly with environmental conditions and was mainly limited by the high contribution of diffuse UVR, irrespective of hat style. Larger brim sizes afforded greater facial protection than smaller brim sizes except around midday when the sun position is high. CONCLUSION: Consideration of diffuse and reflected UVR in sun educational messages could improve sun protection effectiveness.


Asunto(s)
Vestuario , Cara , Estaciones del Año , Neoplasias Cutáneas/prevención & control , Piel , Luz Solar/efectos adversos , Rayos Ultravioleta/efectos adversos , Humanos
7.
Photochem Photobiol ; 87(3): 721-8, 2011.
Artículo en Inglés | MEDLINE | ID: mdl-21223287

RESUMEN

Exposure to solar ultraviolet (UV) light is the main causative factor for skin cancer. UV exposure depends on environmental and individual factors. Individual exposure data remain scarce and development of alternative assessment methods is greatly needed. We developed a model simulating human exposure to solar UV. The model predicts the dose and distribution of UV exposure received on the basis of ground irradiation and morphological data. Standard 3D computer graphics techniques were adapted to develop a rendering engine that estimates the solar exposure of a virtual manikin depicted as a triangle mesh surface. The amount of solar energy received by each triangle was calculated, taking into account reflected, direct and diffuse radiation, and shading from other body parts. Dosimetric measurements (n = 54) were conducted in field conditions using a foam manikin as surrogate for an exposed individual. Dosimetric results were compared to the model predictions. The model predicted exposure to solar UV adequately. The symmetric mean absolute percentage error was 13%. Half of the predictions were within 17% range of the measurements. This model provides a tool to assess outdoor occupational and recreational UV exposures, without necessitating time-consuming individual dosimetry, with numerous potential uses in skin cancer prevention and research.


Asunto(s)
Modelos Teóricos , Dosis de Radiación , Piel/efectos de la radiación , Simulación por Computador , Relación Dosis-Respuesta en la Radiación , Exposición a Riesgos Ambientales , Humanos , Maniquíes , Radiometría , Neoplasias Cutáneas/prevención & control , Luz Solar
8.
Artículo en Inglés | MEDLINE | ID: mdl-17354902

RESUMEN

This paper presents a novel approach for multi-organ (musculoskeletal system) automatic registration and segmentation from clinical MRI datasets, based on discrete deformable models (simplex meshes). We reduce the computational complexity using multi-resolution forces, multi-resolution hierarchical collision handling and large simulation time steps (implicit integration scheme), allowing real-time user control and cost-efficient segmentation. Radial forces and topological constraints (attachments) are applied to regularize the segmentation process. Based on a medial axis constrained approximation, we efficiently characterize shapes and deformations. We validate our methods for the hip joint and the thigh (20 muscles, 4 bones) on 4 datasets: average error = 1.5 mm, computation time = 15 min.


Asunto(s)
Algoritmos , Interpretación de Imagen Asistida por Computador/métodos , Imagenología Tridimensional/métodos , Imagen por Resonancia Magnética/métodos , Modelos Anatómicos , Modelos Biológicos , Sistema Musculoesquelético/anatomía & histología , Reconocimiento de Normas Patrones Automatizadas/métodos , Simulación por Computador , Humanos , Aumento de la Imagen/métodos , Reproducibilidad de los Resultados , Sensibilidad y Especificidad
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