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1.
Tuberc Respir Dis (Seoul) ; 86(2): 82-93, 2023 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-36597583

RESUMEN

Tuberculosis (TB) is a significant public health concern. Globally, TB is among the top 10 and the leading cause of death due to a single infectious agent. Providing standard anti-TB therapy for at least 6 months is recommended as one of the crucial strategies to control the TB epidemic. However, the long duration of TB treatment raised the issue of non-adherence. Non-adherence to TB therapy could negatively affect clinical and public health outcomes. Thus, directly observed therapy (DOT) has been introduced as a standard strategy to improve anti-TB medication adherence. Nonetheless, the DOT approach has been criticized due to inconvenience, stigma, reduced economic productivity, and reduced quality of life, which ultimately could complicate adherence issues. Apart from that, its effectiveness in improving anti-TB adherence is debatable. Therefore, digital technology could be an essential tool to enhance the implementation of DOT. Incorporating the health belief model (HBM) into digital technology can further increase its effectiveness in changing behavior and improving medication adherence. This article aimed to review the latest evidence regarding TB medication non-adherence, its associated factors, DOT's efficacy and its alternatives, and the use of digital technology and HBM in improving medication adherence. This paper used the narrative review methodology to analyze related articles to address the study objectives. Conventional DOT has several disadvantages in TB management. Integrating HBM in digital technology development is potentially effective in improving medication adherence. Digital technology provides an opportunity to improve medication adherence to overcome various issues related to DOT implementation.

2.
Trop Med Infect Dis ; 7(8)2022 Aug 11.
Artículo en Inglés | MEDLINE | ID: mdl-36006270

RESUMEN

Despite the reduction in the number of cases of human malaria throughout the world, the incidence rate of knowlesi malaria is continuing to rise, especially in Southeast Asia. The conventional strategies for the prevention and control of human malaria can provide some protection against knowlesi malaria. Despite the numerous studies on the risk factors and the innovative methods that may be used to prevent and control the vectors of Plasmodium knowlesi, the incidence rate remains high. An integrated approach that includes environmental intervention should be adopted in order to ensure the successful control of zoonotic malaria. A combination of personal-level protection, vector control and environmental control may mitigate the risk of Plasmodium knowlesi transmission from macaques to humans and, ultimately, reduce the incidence rate of knowlesi malaria.

3.
Vaccines (Basel) ; 10(7)2022 Jun 24.
Artículo en Inglés | MEDLINE | ID: mdl-35891181

RESUMEN

(1) Background: Vaccine hesitancy is recognized as an important issue globally and healthcare workers (HCWs) have a powerful influence on the public. Recent studies have reported that there are increasing numbers of vaccine hesitancies among HCWs. This study was conducted to assess the knowledge and attitudes on childhood vaccinations among HCWs in Hospital Universiti Sains Malaysia (HUSM). (2) Methods: This is a cross-sectional study conducted among one hundred and ninety-eight HCWs in HUSM, Kubang Kerian, Kelantan who were selected via convenient sampling. Data on their socio-demographic details, working experience, and main source of information regarding childhood vaccination were collected. A validated, Malay version of the knowledge and attitude on childhood vaccination (KACV) questionnaire was used during the study. (3) Results: Female (OR (95% CI):3.15, (1.39, 7.12), p < 0.05) and a higher education level (degree and above) (OR (95% CI): 2.36 (1.14, 4.89), p < 0.05) are significantly associated with good knowledge. Respondents with a history of side effects of the vaccines among their relatives were about 66% less likely to have good knowledge (OR (95% CI): 0.342 (0.16, 0.73), p < 0.05). A positive attitude towards childhood vaccination was significantly associated with a higher level of education participants, who had significantly better knowledge than participants with a lower education level (OR (95% CI): 3.81, (1.92, 7.57), p < 0.001). On the contrary, participants having direct contact with patients were less likely to have a good attitude towards childhood vaccination (OR (95% CI): 0.207 (0.043, 0.10), p < 0.05), and those with a history of severe side effects of the vaccines among their relatives were also significantly associated with a poor attitude towards childhood vaccination (OR (95% CI: 0.342 (0.16, 0.76), p < 0.05).; (4) Conclusions: The survey findings showed a good level of knowledge and a good attitude of participants towards childhood vaccination. Good knowledge is important for the HCWs to have a favourable attitude to educate the general population on childhood vaccination.

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