RESUMEN
Objective: It remains unknown whether calcium metabolism has any effect on the clinical presentation of superior semicircular canal dehiscence (SSCD). Our aim was to analyse the adjusted calcium and vitamin D levels in SSCD patients compared to a control group. Methods: This was a prospective case-control study performed in a tertiary referral center, university teaching hospital in the UK. It included all new patients with SSCD seen in a dedicated skull base clinic over a 5-year period (2015-2019) compared to a gender and age matched control group. The main outcome of the study was adjusted calcium and Vitamin D levels between the two groups. Results: A total of 31 SSCD patients were recruited with a matched number of control patients. The mean Vitamin D level on the SSCD group was 44.8 nmoL/l (SD: 20.8) compared to 47.5 nmoL/l (SD: 27.4) on the control group (p = 0.702). Mean Adjusted calcium level was 2.34 mmoL/l (SD: 0.7) for SSCD compared to 2.41 mmoL/l (SD: 0.11) for controls (p = 0.01), being within normal limits for both the SSCD and the control group. Conclusion: Our study did not identify a link between Vitamin D levels and presence of SSCD. Normal adjusted calcium values were found in both groups. Despite that a statistically significant lower calcium level was found in the SSCD group which could indicate that suboptimal levels of calcium may affect the micro-environment of the otic capsule at the SSC region.
Asunto(s)
Enfermedades del Oído/cirugía , Endoscopía/métodos , Procedimientos Quirúrgicos Otológicos/métodos , Dimensión del Dolor , Dolor Postoperatorio/tratamiento farmacológico , Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad , Dolor Postoperatorio/clasificación , Estudios ProspectivosAsunto(s)
Neoplasias Orofaríngeas/mortalidad , Neoplasias Orofaríngeas/virología , Infecciones por Papillomavirus/mortalidad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Factores de Riesgo , Escocia/epidemiología , Factores Socioeconómicos , Análisis de SupervivenciaAsunto(s)
Rinorrea de Líquido Cefalorraquídeo/cirugía , Endoscopía/métodos , Procedimientos Quirúrgicos Otorrinolaringológicos/métodos , Base del Cráneo/cirugía , Adulto , Anciano , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Polidioxanona , Diseño de Prótesis , Implantación de Prótesis , Estudios Retrospectivos , Resultado del TratamientoRESUMEN
Foreign bodies are commonly seen by the Ear, Nose and Throat emergency team with cotton wool being the most common aural foreign body seen in the adult population. Most complications secondary to aural foreign bodies described in the literature are minor and rarely require any surgical intervention. Here, we present two cases with impacted cotton wool as aural foreign bodies which resulted in suppurative labyrinthitis and osteomyelitis causing profound sensorineural hearing. These cases highlight the importance of considering aural foreign bodies in the differential diagnosis in those presenting with unilateral symptoms as significant complications, although rare, can occur, particularly in those with delayed diagnosis.
Asunto(s)
Conducto Auditivo Externo/microbiología , Enfermedades del Oído/microbiología , Cuerpos Extraños/complicaciones , Pérdida Auditiva Sensorineural/etiología , Otitis Media Supurativa/diagnóstico , Antibacterianos/administración & dosificación , Antibacterianos/uso terapéutico , Diagnóstico Diferencial , Conducto Auditivo Externo/patología , Enfermedades del Oído/tratamiento farmacológico , Enfermedades del Oído/patología , Enfermedades del Oído/cirugía , Femenino , Cuerpos Extraños/diagnóstico , Cuerpos Extraños/tratamiento farmacológico , Cuerpos Extraños/cirugía , Pérdida Auditiva Sensorineural/diagnóstico , Humanos , Laberintitis/microbiología , Imagen por Resonancia Magnética/métodos , Masculino , Apófisis Mastoides/diagnóstico por imagen , Apófisis Mastoides/patología , Persona de Mediana Edad , Osteomielitis/diagnóstico , Osteomielitis/etiología , Otitis Media Supurativa/etiología , Resultado del TratamientoRESUMEN
Management of third and fourth branchial cleft anomalies are similar. These anomalies should be suspected in a child with recurrent low-anterior neck abscess. Investigations in the form of cross-sectional studies and examination of the pharynx under anaesthesia will facilitate diagnosis and resolution of abscess. Spontaneous closure of the pyriform sinus can occur following conservative management with antibiotic treatment and abscess drainage. This emphasise the role of second-look prior to implementing endoscopic cauterisation or surgery.
Asunto(s)
Absceso/cirugía , Región Branquial/anomalías , Seno Piriforme/anomalías , Absceso/diagnóstico por imagen , Absceso/tratamiento farmacológico , Combinación Amoxicilina-Clavulanato de Potasio/administración & dosificación , Drenaje , Femenino , Humanos , Lactante , Cuello/diagnóstico por imagen , Cuello/cirugía , Remisión Espontánea , Tomografía Computarizada por Rayos X , Ultrasonografía , Inhibidores de beta-Lactamasas/administración & dosificaciónRESUMEN
Patients with cystic fibrosis (CF) are at increased risk of nasal polyps. We present the case of a 17-month-old Caucasian patient with CF who presented with hypertelorism causing cycloplegic astigmatism, right-sided mucoid discharge, snoring and noisy breathing. Imaging suggested bilateral mucoceles in the ethmoid sinuses. Intraoperatively, bilateral soft tissue masses were noted, and both posterior choanae were patent. Polypectomy and bilateral mega-antrostomies were performed. Histological examination revealed inflammatory nasal polyposis typical of CF. The role of early functional endoscopic sinus surgery (FESS) in children with CF nasal polyposis remains questionable as the recurrence rate is higher, and no improvement in pulmonary function has been shown. Our case, however, clearly demonstrates the beneficial upper airway symptom relief and normalisation of facial appearance following FESS in a child with this condition.
Asunto(s)
Fibrosis Quística/complicaciones , Fibrosis Quística/cirugía , Endoscopía , Pólipos Nasales/complicaciones , Pólipos Nasales/cirugía , Antiinflamatorios/uso terapéutico , Betametasona/uso terapéutico , Fibrosis Quística/microbiología , Diagnóstico Diferencial , Enterobacteriaceae/aislamiento & purificación , Infecciones por Enterobacteriaceae/tratamiento farmacológico , Infecciones por Enterobacteriaceae/microbiología , Infecciones por Enterobacteriaceae/patología , Senos Etmoidales/microbiología , Senos Etmoidales/patología , Sinusitis del Etmoides/etiología , Sinusitis del Etmoides/microbiología , Sinusitis del Etmoides/cirugía , Estudios de Seguimiento , Humanos , Lactante , Masculino , Cavidad Nasal/microbiología , Cavidad Nasal/patología , Pólipos Nasales/diagnóstico , Pólipos Nasales/microbiología , Solución Salina Hipertónica/uso terapéutico , Resultado del TratamientoRESUMEN
Mesenteric paraganglioma is a rare tumour with only 17 known published case reports so far. This is the second case that demonstrates lymphovascular invasion of the tumour and the third that exhibits its malignant potential. We present a case of a 69-year-old woman with a large palpable abdominal mass that was thought to arise from the ovary following a staging CT scan. Intraoperatively, a large ovoid mass measuring 18â cm×15â cm ×11.5â cm was found on the small bowel mesentery. Histological examination revealed the characteristic Zellbalen pattern with lymphovascular involvement. Mesenteric paraganglioma is rare and remains a diagnostic dilemma. Although the majority of paragangliomas are non-functional and do not show any malignant potential, individual case-based management is needed in view of their unpredictable nature. A multidisciplinary approach with genetic counselling and long-term follow-up are usually necessary to monitor for future disease recurrence.