Effect of Physical Activity Intervention in Prediabetes: A Systematic Review With Meta-analysis.

BACKGROUND: Prediabetes is a strong risk factor for the development of Type2 Diabetes Mellitus (T2DM). Modification in lifestyle plays an important role to avoid the prognosis of T2DM and its complications in future. The aim of our study was to focus on the effectiveness of physical activity (PA) intervention program on different outcome measures in individuals with prediabetes. The effort of the present review was to contribute to the existing literature by strengthening the evidence pointing toward the positive impact of physical activity in individuals with prediabetes. METHODS: Studies have been identified through database like PubMed, Scopus, and ProQuest. Randomized and nonrandomized controlled trials have been included. Nineteen articles have been selected for the qualitative analysis and 08 for meta-analysis. RESULTS: PA intervention showed a favorable effect on improving oral glucose tolerance (Risk ratio [RR] -0.26, 95% CI -0.06 to 0.07) and fasting blood sugar (RR -0.05, 95% CI -0.14 to 0.04). It also showed the favorable effect on glycated hemoglobin (HbA1C), maximum oxygen uptake (VO2max), and body composition. CONCLUSION: Present review suggests that the PA promotion and participation can help to slow down the progression of disease in individuals with prediabetes and thus reduces the morbidity and mortality associated with T2DM.

A descriptive assessment of oral hygiene and salivary parameters among identical and non- identical twins

AIM: This study was to evaluate saliva parameters of identical and non identical twins with their dental caries and oral hygiene status. MATERIAL AND METHODS: A cross sectional study was conducted to assess the oral health status and investigate the salivary parameters of identical and non­identical twins in Kodhini Village, Kerala. The WHO Oral Health Assessment Form was used to record the oral health status. The Simplified Oral Hygiene Index and Gingival Bleeding Index were also included. Unstimulated saliva was collected. Immunoglobulin A levels in saliva was estimated by Turbidimetric Immunoassay. Salivary Cortisol was analysed using ELISA method. For TAC thiobarbituric acid reactive from Fenton's reaction. RESULTS: Since the absolute difference of the salivary parameters between the pairs of twins was not symmetrically distributed, we report median and interquartile range to describe these differences. There were no observed significant variations in the above salivary parameters. CONCLUSION: The similarity in their environmental factors as well as perhaps the similar genetic predisposition on salivary factors has led to the similarity in the dental caries experience in these twin children.