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1.
J Glob Antimicrob Resist ; 36: 200-209, 2024 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-38211660

RESUMEN

OBJECTIVES: To retrospectively describe the patterns of use of dalbavancin for treating infections in diabetic patients in Italian and Spanish standard clinical practice. METHODS: DALBADIA [NCT04959799] was a multicentre, observational, retrospective cohort study, conducted in Italy and Spain. The study enrolled 97 adults with type 1 or 2 diabetes mellitus, treated with dalbavancin as per standard clinical practice for a Gram-positive bacterial infection or the Gram-positive component of a mixed infection. RESULTS: Dalbavancin was used to treat cellulitis (18/92 patients, 19.6%), followed by prosthetic joint infection (14 patients, 15.2%), endocarditis (13 patients, 14.1%), and primary bacteraemia (10 patients, 10.9%); 78/92 (84.8%) patients had Gram-positive infections only, and 14 (15.2%) had mixed infections. The most frequently isolated microorganisms were Staphylococcus aureus in 43 (55.8% of the patients with microbial isolation), 25.6% of which methicillin-resistant; Staphylococcus epidermidis in 13 (16.9%), 53.8% of which methicillin-resistant; Enterococcus faecalis in 11 (14.3%). The main reason for the dalbavancin choice was the intent to simplify the antibiotic regimen (81.5% of cases). A multidisciplinary team participated in the treatment choice process for 53 (57.6%) patients. Dalbavancin was given as first-line antibiotic in 34 (37.0%) patients and administered as one infusion in 32 (34.8%), and as two infusions in 39 (42.4%). In total, 57/62 (91.9%) eligible patients with available assessment were judged clinically cured or improved at the end of observation. CONCLUSION: In clinical practice, dalbavancin was used in diabetic patients to treat ABSSSIs and other difficult-to-treat infections with a favourable safety profile and a high rate of positive clinical responses.


Asunto(s)
Antibacterianos , Diabetes Mellitus , Teicoplanina , Adulto , Humanos , Italia , Estudios Retrospectivos , España , Teicoplanina/análogos & derivados
2.
Med. clín (Ed. impr.) ; 162(1): 15-18, ene. 2024. tab
Artículo en Inglés | IBECS | ID: ibc-229041

RESUMEN

Objetivo Corynebacterium striatum (C. striatum) es un microorganismo emergente en la infección de pie diabético poco estudiado. El objetivo es evaluar los factores de riesgo (FR) relacionados con osteomielitis por C. striatum en paciente con pie diabético. Métodos Estudio casos-controles en la Unidad de Pie Diabético entre 2015 y 2021. Un número de 44 pacientes con osteomielitis por C. striatum (casos) y 44 con osteomielitis por microorganismo distinto (controles) fueron incluidos. Resultados Enfermedad arterial periférica (odds ratio [OR]: 2,8, p = 0,037), fibrilación auricular (OR: 3,7, p = 0,034), pie diabético isquémico (OR: 3,3, p = 0,020) y antibioterapia previa prolongada más de 14 días (OR: 3,4, p = 0,012) fueron FR para la osteomielitis por C. striatum. En el análisis multivariado la antibioterapia más de 14 días fue el único FR independiente (OR: 3,46; p = 0,017) para osteomielitis por C. striatum. Conclusiones La antibioterapia previa recibida durante más de 14 días es un FR independiente y estadísticamente significativo de osteomielitis por C. striatum en pacientes con pie diabético (AU)


Objective Corynebacterium striatum (CS) is an emerging micro-organism in diabetic foot infection for which there are currently few studies. The objective was to analyze the risk factors (RF) related to CS osteomyelitis in patients with diabetic foot. Methods A case–control study was conducted in the Diabetic Foot Unit between 2015 and 2021. Forty-four patients with osteomyelitis due to CS (cases) and 44 patients with osteomyelitis due a different micro-organism (controls) were included. Results Peripheral artery disease (OR: 2.8, p = 0.037), atrial fibrillation (OR: 3.7, p = 0.034), ischemic diabetic foot (OR: 3.3, p = 0.020) and previous prolonged antibiotic therapy more than 14 days (OR: 3.4, p = 0.012) were identified as RF for osteomyelitis due to CS. When performing the multivariate analysis antibiotic therapy >14 days was independent RF (OR: 3.46; p = 0.017). Conclusions Previous antibiotic therapy received more than 14 days is an independent and statistically significant RF for CS osteomyelitis in patients with diabetic foot (AU)


Asunto(s)
Humanos , Masculino , Femenino , Persona de Mediana Edad , Anciano , Infecciones por Corynebacterium/diagnóstico , Infecciones por Corynebacterium/microbiología , Osteomielitis/microbiología , Pie Diabético/microbiología , Estudios de Casos y Controles
3.
Artículo en Inglés | MEDLINE | ID: mdl-36624032

RESUMEN

INTRODUCTION: Respiratory syncytial virus (RSV) causes an acute respiratory illness similar to influenza, although there are few data comparing both of them in adults. The existence of clinical differences between these two infections could have implications for their management. MATERIALS AND METHODS: Retrospective observational cohort study including 63 adults with positive PCR for RSV and 221 for influenza during winter 2018-2019. Epidemiological, clinical characteristics and outcomes were contrasted between both groups. RESULTS: Compared to influenza, RSV-positive patients presented a higher association with active neoplasia (OR=2.9; 95% CI: 1.2-6.9), dependence for basic activities of daily living (OR=3.4; 95% CI: 1.4-8.2) and immunosuppression due to chronic glucocorticoid administration (OR=7.6; 95% CI: 1.6-36.1). At diagnosis, fever was less common (OR=0.3; 95% CI: 0.2-0.7), and C-reactive protein level ≥100mg/l was more frequent (OR=2.1; 95% CI: 1.0-4.5). They developed bacterial co-infection by Staphylococcus aureus in a higher proportion (OR=8.3; 95% CI: 1.5-46.9) and presented a greater need for admission to the intensive care unit (OR=5.4; 95% CI: 1.4-19.2). CONCLUSION: RSV is an important cause of respiratory illness in adults during the influenza season. It especially affects vulnerable patients with chronic underlying diseases, and has a higher morbidity than influenza. For all these reasons, specific detection, prevention and treatment of RSV is necessary in order to reduce the consumption of health care resources due to RSV disease in adults.


Asunto(s)
Gripe Humana , Infecciones por Virus Sincitial Respiratorio , Virus Sincitial Respiratorio Humano , Adulto , Humanos , Infecciones por Virus Sincitial Respiratorio/complicaciones , Infecciones por Virus Sincitial Respiratorio/epidemiología , Gripe Humana/complicaciones , Gripe Humana/epidemiología , Gripe Humana/diagnóstico , Estudios Retrospectivos , Actividades Cotidianas , Enfermedad Crónica
4.
Med Clin (Barc) ; 162(1): 15-18, 2024 01 12.
Artículo en Inglés, Español | MEDLINE | ID: mdl-37981483

RESUMEN

OBJECTIVE: Corynebacterium striatum (CS) is an emerging micro-organism in diabetic foot infection for which there are currently few studies. The objective was to analyze the risk factors (RF) related to CS osteomyelitis in patients with diabetic foot. METHODS: A case-control study was conducted in the Diabetic Foot Unit between 2015 and 2021. Forty-four patients with osteomyelitis due to CS (cases) and 44 patients with osteomyelitis due a different micro-organism (controls) were included. RESULTS: Peripheral artery disease (OR: 2.8, p = 0.037), atrial fibrillation (OR: 3.7, p = 0.034), ischemic diabetic foot (OR: 3.3, p = 0.020) and previous prolonged antibiotic therapy more than 14 days (OR: 3.4, p = 0.012) were identified as RF for osteomyelitis due to CS. When performing the multivariate analysis antibiotic therapy >14 days was independent RF (OR: 3.46; p = 0.017). CONCLUSIONS: Previous antibiotic therapy received more than 14 days is an independent and statistically significant RF for CS osteomyelitis in patients with diabetic foot.


Asunto(s)
Diabetes Mellitus , Pie Diabético , Osteomielitis , Humanos , Pie Diabético/complicaciones , Pie Diabético/terapia , Estudios de Casos y Controles , Osteomielitis/etiología , Osteomielitis/microbiología , Factores de Riesgo , Antibacterianos/uso terapéutico , Diabetes Mellitus/tratamiento farmacológico
6.
Enferm. infecc. microbiol. clín. (Ed. impr.) ; 41(7): 423-425, Agos-Sept- 2023. tab
Artículo en Español | IBECS | ID: ibc-223717

RESUMEN

Introducción: Una de las estrategias más importantes de los PROA en los Servicios de Urgencias (SU) es el diagnóstico adecuado de infección para evitar la prescripción inadecuada. Nuestro objetivo es evaluar a los pacientes que reciben antibiótico a pesar de no tener datos objetivos de infección. Métodos: Realizamos un estudio transversal de los pacientes ingresados en el SU del Hospital Universitario Fundación Alcorcón durante 2 meses (mayo del 2019 y marzo del 2021) en los que se recomendó suspender el antibiótico a través del PROA. Se analizaron las características clínicas y epidemiológicas, y el seguimiento a 30 días para valorar los reingresos y la mortalidad. Resultados: Se analizaron 145 pacientes. Se recomendó suspender el antibiótico en 25. El 44% de ellos tenían diagnóstico de infección urinaria. La recomendación de suspensión se aceptó en el 88%. Ningún paciente falleció y uno reingresó. Conclusiones: Un porcentaje importante de pacientes tenían prescrito antibiótico a pesar de no tener criterios de infección, siendo la evolución clínica tras la de prescripción favorable.(AU)


Introduction: One of the most important strategies of PROA in the Emergency Department (ED) is the accurate diagnosis of infection to avoid inappropriate prescription. Our objective is to evaluate patients who receive antibiotics despite not having objective data of infection. Methods: We carried out a cross-sectional study of patients admitted to the ED of the Hospital Universitario Fundación Alcorcón in which it was recommended to suspend the antibiotic through the PROA. Clinical and epidemiological characteristics and 30-day follow-up were analyzed to assess readmissions and mortality. Results: 145 patients were analyzed. It was recommended to suspend the antibiotic in 25. 44% of them had a diagnosis of urinary infection. The suspension recommendation was accepted by 88%. No patient died and one was readmitted. Conclusions: An important percentage of patients are prescribed antibiotics despite not having infection criteria, the clinical evolution after suspension of antibiotics was favorable.(AU)


Asunto(s)
Humanos , Retirada de Medicamento por Seguridad , Quimioterapia , Pacientes/estadística & datos numéricos , Servicios Médicos de Urgencia , Infecciones , Estudios Transversales
8.
Enferm. infecc. microbiol. clín. (Ed. impr.) ; 42(2): 62-68, Feb. 2024. tab, ilus, graf
Artículo en Español | IBECS | ID: ibc-230267

RESUMEN

Introducción: El virus respiratorio sincitial (VRS) produce una enfermedad respiratoria aguda parecida a la gripe, aunque en adultos existen pocos datos que las comparen. La existencia de diferencias clínicas entre ambas infecciones podría conllevar implicaciones en su manejo. Materiales y métodos: Estudio observacional de cohortes retrospectivo incluyendo 63 adultos con PCR positiva para VRS y 221 para gripe durante el invierno 2018-2019. Se contrastaron las características epidemiológicas, clínicas y desenlaces entre ambos grupos. Resultados: En comparación con la gripe los pacientes VRS positivos asociaron mayor relación con neoplasia activa (OR=2,9; IC 95%: 1,2-6,9), dependencia para las actividades básicas de la vida diaria (OR=3,4; IC 95%: 1,4-8,2) e inmunosupresión por administración crónica de glucocorticoides (OR=7,6; IC 95%: 1,6-36,1). Al diagnóstico era menos común la presencia de fiebre (OR=0,3; IC 95%: 0,2-0,7) y más frecuente un nivel de proteína C reactiva≥100mg/l (OR=2,1; IC 95%: 1,0-4,5). Desarrollaron coinfección bacteriana por Staphylococcus aureus en mayor proporción (OR=8,3; IC 95%: 1,5-46,9) y presentaron una mayor necesidad de ingreso en la unidad de cuidados intensivos (OR=5,4; IC 95%: 1,4-19,2). Conclusión: El VRS es una causa importante de enfermedad respiratoria en adultos durante la época de gripe. Afecta especialmente a pacientes vulnerables con enfermedades crónicas de base, y presenta una morbilidad clínica superior a la gripe. Por todo ello es necesaria la detección, prevención y tratamiento específicos del VRS con el objetivo de reducir el consumo de recursos sanitarios que supone la enfermedad por VRS en adultos.(AU)


Introduction: Respiratory syncytial virus (RSV) causes an acute respiratory illness similar to influenza, although there are few data comparing both of them in adults. The existence of clinical differences between these two infections could have implications for their management. Materials and methods: Retrospective observational cohort study including 63 adults with positive PCR for RSV and 221 for influenza during winter 2018–2019. Epidemiological, clinical characteristics and outcomes were contrasted between both groups. Results: Compared to influenza, RSV-positive patients presented a higher association with active neoplasia (OR=2.9; 95% CI: 1.2–6.9), dependence for basic activities of daily living (OR=3.4; 95% CI: 1.4–8.2) and immunosuppression due to chronic glucocorticoid administration (OR=7.6; 95% CI: 1.6–36.1). At diagnosis, fever was less common (OR=.3; 95% CI: .2–.7), and C-reactive protein level ≥100mg/L was more frequent (OR=2.1; 95% CI: 1.0–4.5). They developed bacterial co-infection by Staphylococcus aureus in a higher proportion (OR=8.3; 95% CI: 1.5–46.9) and presented a greater need for admission to the intensive care unit (OR=5.4; 95% CI: 1.4–19.2). Conclusion: RSV is an important cause of respiratory illness in adults during the influenza season. It especially affects vulnerable patients with chronic underlying diseases, and has a higher clinical morbidity than influenza. For all these reasons, specific detection, prevention and treatment of RSV is necessary in order to reduce the consumption of health care resources due to RSV disease in adults.(AU)


Asunto(s)
Humanos , Masculino , Femenino , Adulto , Infecciones por Virus Sincitial Respiratorio , Gripe Humana , Infecciones del Sistema Respiratorio , Enfermedades Respiratorias , Estudios Retrospectivos , Estudios de Cohortes , Microbiología , Enfermedades Transmisibles
9.
Artículo en Inglés | MEDLINE | ID: mdl-36347790

RESUMEN

INTRODUCTION: One of the most important strategies of PROA in the Emergency Department (ED) is the accurate diagnosis of infection to avoid inappropriate prescription. Our objective is to evaluate patients who receive antibiotics despite not having objective data of infection. METHODS: We carried out a cross-sectional study of patients admitted to the ED of the Hospital Universitario Fundación Alcorcón in which it was recommended to suspend the antibiotic through the PROA. Clinical and epidemiological characteristics and 30-day follow-up were analyzed to assess readmissions and mortality. RESULTS: 145 patients were analyzed. It was recommended to suspend the antibiotic in 25. 44% of them had a diagnosis of urinary infection. The suspension recommendation was accepted by 88%. No patient died and one was readmitted. CONCLUSIONS: An important percentage of patients are prescribed antibiotics despite not having infection criteria, the clinical evolution after suspension of antibiotics was favorable.

10.
Enferm. infecc. microbiol. clín. (Ed. impr.) ; 40(6): 296-301, Jun-Jul, 2022. tab
Artículo en Español | IBECS | ID: ibc-206891

RESUMEN

Objetivo: Describir la experiencia clínica con dalbavancina en el tratamiento de la infección de pie diabético en una unidad multidisciplinar de un hospital de segundo nivel. Métodos: Estudio descriptivo retrospectivo de pacientes con infección de pie diabético tratados con dalbavancina en la Unidad de Pie Diabético del Hospital Universitario Fundación Alcorcón de septiembre de 2016 a diciembre de 2019. Se recogieron parámetros demográficos y comorbilidades, características de la infección y del tratamiento con dalbavancina. Se estimó la tasa de curación a los 90 días tras finalizar el tratamiento. Resultados: Un total de 23 pacientes con infección de pie diabético (osteomielitis) fueron tratados con dalbavancina; 19 eran hombres con una edad media de 65 años. Los microorganismos más frecuentemente aislados fueron Staphylococcus aureus (11) y Corynebacterium striatum (7). En 22 casos se usó dalbavancina como terapia de segunda elección, en 11 debido a toxicidad de otros antibióticos. La mediana de duración del tratamiento fue de 5 (4-7) semanas; la dosis más frecuente de dalbavancina (8 pacientes) fue de 1.000mg seguido de 500mg semanales durante 5 semanas. Tres pacientes presentaron efectos secundarios leves (náuseas y molestias gastrointestinales). A los 90 días de finalizar el tratamiento, el 87% (20) de los pacientes se curaron (IC95%: 65,2-94,52%). Conclusión: Los pacientes con osteomielitis por microorganismos grampositivos que recibieron como parte del tratamiento multidisciplinar antibioterapia con dalbavancina tuvieron una elevada tasa de curación, con una adecuada tolerancia y escasos efectos secundarios. Dalbavancina ofrece una alternativa segura en el tratamiento de la infección profunda de pie diabético.(AU)


Objective: To describe the clinical experience with dalbavancin in the treatment of diabetic foot infection in a multidisciplinary unit of a second level hospital. Methods: A retrospective, descriptive study was made with all patients with diabetic foot infection treated with dalbavancin in the Diabetic Foot Unit of Hospital Universitario Fundación Alcorcón, covering the period from September 2016 to December 2019. Demographic parameters and comorbidities, characteristics of the infection and treatment with dalbavancin were recorded. The cure rate was estimated at 90 days after finishing the treatment. Results: A total of 23 patients with diabetic foot infection (osteomyelitis) started treatment with dalbavancin, 19 were men and the mean age was 65 years. The microorganisms most frequently isolated for the indication of treatment with dalbavancin were Staphylococcus aureus (11) and Corynebacterium striatum (7). Dalbavancin was used as a second choice therapy in 22 cases, in 11 due to toxicity from other antibiotics. The median duration of treatment was 5 (4-7) weeks; the most frequent dose of dalbavancin (8 patients) was 1000mg followed by 500mg weekly for 5 weeks. 3 patients presented mild side effects (nausea and gastrointestinal discomfort). At 90 days after completion of dalbavancin therapy, 87% (20) of the patients were cured (95% CI: 65.2%-94.52%). Conclusion: Patients with osteomyelitis due to gram-positive microorganisms who received as part of the multidisciplinary antibiotic treatment with dalbavancin, had a high rate of cure with adequate tolerance and few side effects. Dalbavancin offers a safe alternative in treating deep diabetic foot infection.(AU)


Asunto(s)
Humanos , Masculino , Femenino , Adulto , Persona de Mediana Edad , Anciano , Anciano de 80 o más Años , Pie Diabético/complicaciones , Pie Diabético/tratamiento farmacológico , Pie Diabético/microbiología , Antiinfecciosos , Staphylococcus aureus , Corynebacterium , Diabetes Mellitus/tratamiento farmacológico , Osteomielitis/complicaciones , Osteomielitis/tratamiento farmacológico , Osteomielitis/microbiología , Microbiología , Enfermedades Transmisibles , Epidemiología Descriptiva
11.
Artículo en Inglés | MEDLINE | ID: mdl-35490091

RESUMEN

OBJECTIVE: To describe the clinical experience with dalbavancin in the treatment of diabetic foot infection in a multidisciplinary unit of a second level hospital. METHODS: A retrospective, descriptive study was made with all patients with diabetic foot infection treated with dalbavancin in the Diabetic Foot Unit of Hospital Universitario Fundación Alcorcón, covering the period from September 2016 to December 2019. Demographic parameters and comorbidities, characteristics of the infection and treatment with dalbavancin were recorded. The cure rate is estimated at 90 days after finishing the treatment. RESULTS: A total of 23 patients with diabetic foot infection (osteomyelitis) started treatment with dalbavancin, 19 were men and the mean age was 65 years. The microorganisms most frequently isolated for the indication of treatment with dalbavancin were Staphylococcus aureus (11) and Corynebacterium striatum (7). Dalbavancin was used as a second choice therapy in 22 cases, in 11 due to toxicity from other antibiotics. The median duration of treatment was 5 (4-7) weeks; the most frequent dose of dalbavancin (8 patients) was 1000 mg followed by 500 mg weekly for 5 weeks. 3 patients presented mild side effects (nausea and gastrointestinal discomfort). At 90 days after completion of dalbavancin therapy, 87% (20) of the patients were cured (95% CI: 65.2%-94.52%). CONCLUSION: Patients with osteomyelitis due to gram-positive microorganisms who received as part of the multidisciplinary antibiotic treatment with dalbavancin, had a high rate of cure with adequate tolerance and few side effects. Dalbavancin offers a safe alternative in treating deep diabetic foot infection.


Asunto(s)
Enfermedades Transmisibles , Diabetes Mellitus , Pie Diabético , Osteomielitis , Anciano , Antibacterianos , Diabetes Mellitus/inducido químicamente , Diabetes Mellitus/tratamiento farmacológico , Pie Diabético/inducido químicamente , Pie Diabético/complicaciones , Pie Diabético/tratamiento farmacológico , Femenino , Humanos , Masculino , Osteomielitis/tratamiento farmacológico , Osteomielitis/microbiología , Estudios Retrospectivos , Teicoplanina/análogos & derivados
12.
Artículo en Inglés, Español | MEDLINE | ID: mdl-33451810

RESUMEN

OBJECTIVE: To describe the clinical experience with dalbavancin in the treatment of diabetic foot infection in a multidisciplinary unit of a second level hospital. METHODS: A retrospective, descriptive study was made with all patients with diabetic foot infection treated with dalbavancin in the Diabetic Foot Unit of Hospital Universitario Fundación Alcorcón, covering the period from September 2016 to December 2019. Demographic parameters and comorbidities, characteristics of the infection and treatment with dalbavancin were recorded. The cure rate was estimated at 90 days after finishing the treatment. RESULTS: A total of 23 patients with diabetic foot infection (osteomyelitis) started treatment with dalbavancin, 19 were men and the mean age was 65 years. The microorganisms most frequently isolated for the indication of treatment with dalbavancin were Staphylococcus aureus (11) and Corynebacterium striatum (7). Dalbavancin was used as a second choice therapy in 22 cases, in 11 due to toxicity from other antibiotics. The median duration of treatment was 5 (4-7) weeks; the most frequent dose of dalbavancin (8 patients) was 1000mg followed by 500mg weekly for 5 weeks. 3 patients presented mild side effects (nausea and gastrointestinal discomfort). At 90 days after completion of dalbavancin therapy, 87% (20) of the patients were cured (95% CI: 65.2%-94.52%). CONCLUSION: Patients with osteomyelitis due to gram-positive microorganisms who received as part of the multidisciplinary antibiotic treatment with dalbavancin, had a high rate of cure with adequate tolerance and few side effects. Dalbavancin offers a safe alternative in treating deep diabetic foot infection.

13.
Artículo en Inglés | MEDLINE | ID: mdl-32312777

RESUMEN

Tedizolid has demonstrated its efficacy and safety in clinical trials; however, data concerning its tolerability in long-term treatments are scarce. The aim of the study was to assess the indications and to describe the long-term safety profile of tedizolid. A multicentric retrospective study of patients who received tedizolid for more than 6 days was conducted. Adverse events (AEs) were identified from patients' medical records and laboratory data. The World Health Organization causality categories were used to discern AEs that were probably associated with tedizolid. Eighty-one patients, treated with tedizolid 200 mg once daily for a median (interquartile range [IQR]) duration of 28 (14 to 59) days, were included; 36 (44.4%) had previously received linezolid. The most common reasons for selecting tedizolid were to avoid linezolid potential toxicities or interactions (53.1%) or due to previous linezolid-related toxicities (27.2%). The most common indications were off-label, including prosthetic joint infections, osteomyelitis, and respiratory infections (77.8%). Overall, 9/81 patients (11.1%) experienced a probably associated AE. Two patients (2.5%) developed gastrointestinal disorders, 1 (1.2%) developed anemia, and 6 developed thrombocytopenia (7.4%) after a median (IQR) duration of treatment of 26.5 (17 to 58.5) days. Four (5%) patients discontinued tedizolid due to AEs. Among 23 patients with chronic renal failure (CRF), the rate of myelotoxicity was 17.4%, and only 8.7% had to stop tedizolid; 20 out of 22 with previous linezolid-associated toxicity had no AE. Long-term tedizolid treatments had good tolerance with rates of gastrointestinal AE and hematological toxicity lower than those reported with linezolid, particularly in patients with CRF and in those with a history of linezolid-associated toxicity.


Asunto(s)
Enfermedades Cutáneas Bacterianas , Antibacterianos/efectos adversos , Humanos , Organofosfatos/efectos adversos , Oxazoles , Oxazolidinonas , Estudios Retrospectivos , Enfermedades Cutáneas Bacterianas/tratamiento farmacológico , Tetrazoles
14.
Rev. esp. quimioter ; 32(6): 539-544, dic. 2019. ilus, tab, graf
Artículo en Español | IBECS | ID: ibc-190613

RESUMEN

OBJETIVOS: Comunicar la actividad de telemedicina, desde su apertura, entre una consulta hospitalaria de enfermedades infecciosas y un centro penitenciario. MATERIAL Y MÉTODOS: Estudio descriptivo de la teleconsulta de enfermedades infecciosas del Hospital Universitario Fundación Alcorcón con el centro penitenciario de Navalcarnero desde 2013 hasta 2017, que se lleva a cabo mediante videoconferencia. Se analizó motivo y número de consultas, diagnóstico de VIH, tratamiento antirretroviral (TAR), situación inmunovirológica, diagnóstico del virus de la hepatitis C (VHC) e intervención realizada por el experto en infecciosas. RESULTADOS: Se valoraron 75 pacientes en un total de 168 consultas (en el primer año 11 consultas y en el quinto 62). El índice de consultas sucesivas/nuevas fue de 1,24 y el 85% de los pacientes requirió menos de 1 año de seguimiento. El 84% de los pacientes no se trasladó al hospital. El 99% de los pacientes aceptó esta modalidad. El 96% era VIH positivo, el 94% de estos tomaba TAR y el 85% tenía carga viral indetectable con 532 CD4/mL de mediana. El 90% tenía serología positiva para VHC. El 72% de las consultas fue para la valoración de tratamiento del VHC, que fue sofosbuvir/ledipasvir en un 63%. Un 40% cambió de TAR (70% para evitar interacciones). CONCLUSIÓN: La mayoría de los pacientes valorados tienen infección por VIH. Esta modalidad de consulta tiene una demanda creciente, es eficiente (evita traslados y es resolutiva) y tiene elevada aceptación. El motivo de consulta más frecuente fue el tratamiento del VHC y más de la tercera parte de los pacientes precisó cambio de TAR


OBJECTIVES: Communicate the activity of telemedicine, from its opening, between a hospital consultation of infectious diseases and a penitentiary center. MATERIAL AND METHODS: Descriptive study of the tele-consultation of infectious diseases of the Alcorcón Foundation University Hospital with the Navalcarnero penitentiary center from 2013 to 2017, which is carried out by videoconference. The reason and number of consultations, diagnosis of HIV, antiretroviral treatment (ART), immunovirological situation, diagnosis of hepatitis C virus (HCV= and intervention performed by the infectious expert were analyzed. RESULTS: A total of 75 patients were evaluated in a total of 168 consultations (in the first year 11 consultations and in the fifth year 62). The index of successive / new consultations was 1.24 and 85% of the patients required less than 1 year of follow-up.84% of patients did not move to the hospital.99% of patients accepted this modality.96% were HIV positive, 94% of them took ART and 85% had undetectable viral load with 532 CD4/mL of medium.90% had positive serology for HCV.72% of the consultations were for the assessment of HCV treatment, which was sofosbuvir/ledipasvir by 63%.40% changed their ART (70% to avoid interactions). CONCLUSION: Most of the evaluated patients have HIV infection. This type of consultation has a growing demand, is efficient (avoids transfers and is decisive) and has high acceptance. The most frequent reason for consultation was the treatment of HCV and more than a third of patients required ART change


Asunto(s)
Humanos , Masculino , Adulto , Persona de Mediana Edad , Infecciones por VIH/diagnóstico , Infecciones por VIH/tratamiento farmacológico , Hepatitis C Crónica/diagnóstico , Hepatitis C Crónica/tratamiento farmacológico , Prisiones , Telemedicina , Estudios Retrospectivos
15.
Educ. med. (Ed. impr.) ; 20(4): 231-237, jul.-ago. 2019. ilus, graf, tab
Artículo en Español | IBECS | ID: ibc-191581

RESUMEN

La formación en seguridad del paciente durante la residencia contribuye a la cultura de la seguridad y a la calidad asistencial. Un currículum para formar en seguridad incorpora distintas actividades formativas a lo largo de la especialidad y adecuadas a cada momento: cursos, talleres, sesiones de incidente crítico, rondas de seguridad, que se han descrito anteriormente, y simulación. La simulación permite el entrenamiento seguro de situaciones clínicas complejas en equipos multiprofesionales. Estructurar el aprendizaje de factor humano mediante el manejo de recursos en las crisis, y proporcionar feedback en el debriefing mejora la competencia. La simulación puede formar parte de la evaluación formativa objetiva de los residentes. Se ha demostrado que tiene resultados en el desempeño de los profesionales sanitarios, mejora la calidad de la asistencia y tiene efectos sobre los pacientes


Patient safety training during residency contributes to the culture of safety and quality of care. Patient safety curriculum incorporates different activities throughout the specialty and appropriate to each moment: courses, workshops, critical incident sessions, safety rounds, which have been described above, and simulation. The simulation allows the safe training of complex clinical situations in multiprofessional teams. Structure the learning of human factor through the management of resources in crises, and provide feedback in debriefing improves competition. The simulation can be part of the objective formative evaluation of the residents. It has been shown to have results in the performance of health professionals, improves the quality of care and has effects on patients


Asunto(s)
Seguridad del Paciente/normas , Internado y Residencia , Simulación de Paciente , Maniquíes , Entrenamiento Simulado/métodos , 28574/historia , Enseñanza Mediante Simulación de Alta Fidelidad/historia , Entrenamiento Simulado/historia
16.
Educ. med. (Ed. impr.) ; 20(3): 170-178, mayo-jun. 2019. tab
Artículo en Español | IBECS | ID: ibc-191570

RESUMEN

La formación en seguridad del paciente durante la residencia contribuye a la cultura de la seguridad y a la calidad asistencial. Un currículum para formar en seguridad incorpora distintas actividades formativas a realizar a lo largo de la especialidad y adecuadas a cada momento formativo. Desde la incorporación del residente, los cursos de seguridad, comunicación, ética, los talleres de lavado de manos, de técnicas, junto con los recursos de Internet, lo van dotando de diferentes competencias. Adquiere la competencia en seguridad con la integración en la actividad asistencial diaria de la valoración de los riesgos, la detección y la comunicación de incidentes, y el análisis de eventos adversos. Acelera el aprendizaje reflexionando de forma estructurada y aprendiendo del error con los incidentes críticos y la simulación


Patient safety training during residency contributes to the culture of safety and quality of care. Patient safety curriculum incorporates different activities to be carried out throughout the residence and appropriate to each training moment. Since the incorporation of the resident the courses of security, communication, ethics, hand washing workshops, techniques, together with Internet resources are endowing him with knowledge and skills. Acquires security competence with the integration of risk assessment, detection and communication of incidents and the analysis of adverse events into the daily assistance activity. Accelerates learning by reflecting in a structured way and learning from error with critical incidents and simulation


Asunto(s)
Humanos , Seguridad del Paciente/normas , Internado y Residencia , Simulación de Paciente , Curriculum , Competencia Clínica , Modelos Educacionales , Garantía de la Calidad de Atención de Salud/métodos , Personal de Salud/educación , Administración de la Seguridad/métodos
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