1.
Org Lett
; 3(18): 2839-42, 2001 Sep 06.
Artículo
en Inglés
| MEDLINE
| ID: mdl-11529770
RESUMEN
[reaction: see text]. Mechanistic studies employing in situ NMR analysis implicate intermediate silicon enolates as reactive intermediates in the Rh-DuPhos catalyzed two-step reductive aldol reaction with Cl(2)MeSiH. These enolates undergo noncatalyzed reaction with a variety of aldehydes to give the derived syn-aldol adduct in high yields and diastereoselection.
2.
Org Lett
; 3(12): 1829-31, 2001 Jun 14.
Artículo
en Inglés
| MEDLINE
| ID: mdl-11405722
RESUMEN
[see reaction]. A catalytic amount of [(cod)IrCl]2 and indane-pybox converts diethylmethylsilane, methyl acrylate, and certain aldehydes to the derived reductive aldol adduct with good enantio- and diastereocontrol.