RESUMEN
Despite the optimal treatment given to children with medulloblastoma, many relapses are seen after combining treatments. Re-irradiation is part of salvage therapy for children who relapse and might provide long-term disease control. Nevertheless, it is challenging because there is a concern about exceeding radiation tolerances and late treatment toxicities. Re-irradiation is an option for many brain tumors, including medulloblastoma in children. This study presents a case of recurrent medulloblastoma treated with re-irradiation. A systematic review of the literature provided up-to-date data on the re-irradiation of medulloblastoma in children. This study aims to contribute to the scarce literature on the treatment strategy, which may help improve patients' outcomes.
RESUMEN
Revascularization strategy for coronary artery disease in diabetic patients remains a field of controversy. Percutaneous coronary intervention has a less favourable outcome in these patients, though drug eluting stents have significantly improved the outcome. Although in most series, the outcome with coronary artery bypass grafting is worse in diabetic populations, surgery seems to be superior to angioplasty, particularly in diabetics with multivessel disease. Results from randomized trials such as the ongoing FREEDOM, CARDia and SYNTAX may define the role of each procedure in the treatment of diabetic patients with coronary artery disease.