[Sertoli-Leydig cell tumor of the ovary: case study of a 22-year old woman]. / Tumeur à cellules de Sertoli-Leydig de l'ovaire: à propos d'un cas chez une jeune fille de 22 ans.

Sertoli-Leydig cell tumors are rare secreting mesenchymal and sex cord-stromal tumors. However, they constitute one type of tumor most often responsible for virilization syndrome. A definite diagnosis is provided by histological examination following surgical excision of the tumor. It has no characterizing features on ultrasonography, in spite of the strong clinical presumption. Like many neoplasias, prognosis is related to the degree of cellular differentiation and to the presence of heterologous elements. The aim of our study was to report the case of a 22-year old woman suffering from a real virilization syndrome secondary to non-epithelial Sertoli-Leydig cell tumor of the ovary. Poorly differentiated Sertoli-Leydig tumors have high malignant potential. Treatment is surgical; taxane-platinum combination chemotherapy is an interesting adjuvant. Prognosis after surgical resection is related to the risk of relapses.

[Cutaneous tuberculosis in Dakar: 151 cases report]. / Tuberculose cutanee a Dakar: a propos de 151 cas.

INTRODUCTION: Cutaneous tuberculosis diagnosis is difficult because of clinical polymorphism. Our goal was to study the clinical, epidemiological and evolutionary characteristics of cutaneous tuberculosis in Dakar. PATIENTS AND METHODS: We performed a retrospective study from 1972 to 2005 of the tuberculosis cutaneous cases in our department. All cases which fulfilled clinical, epidemiological, the tuberculin test positive, bacteriogical and histological characteristics of cutaneous involvement were studied. RESULTS: Our study included 151 cases (75 men, 73 women). Clinical features were: scrofuloderma (84,76%), gomma (11,25%), periorificial tuberculosis (1,98%), lupus tuberculosis (1,98%), verrucosa tuberculosis (2,64%) and BCGite (0,66%). Pulmonary (26,5%), osteoarticular (8,6%), neurological (0,66%) were the man visceral involvements. Tuberculine test was highly positive in 66,22% of cases and HIV test was positive in 14,28%. Healing occurred after 1 or 2 month of treatment in all patients. Recidivation occurred in 3 patients and 3 patients died. Cure occurred in 23 patients after 8 to 12 month of treatment. CONCLUSION: Cutaneous tuberculosis is still endemic in Senegal. Scrofuloderma and gumma are the two main clinical presentations. Diagnosis was based on skin tuberculine test positive and histological granuloma.