RESUMEN
OBJECTIVE: To study the chemical constituents of flower buds of Lonicera similes. METHODS: The chemical constituents were isolated and purified with macroporous resin, silica gel column chromatography, gel chromatography, ect. The structures were elucidated according to the references combined with the application of spectrum techniques such as 1H-NMR, 13C-NMR ect. RESULTS: Nine compounds were isolated and their structures were identified as 5-hydroxyl-7,4'-dimethoxyflavone (I), rutin (II), quercetin (III), amentoflavone (IV), aesculetin (V), beta-sitosterol (VI), 5-hydroxyl-7,3', 4'-trimethoxyflavone (VIII), oleanolic acid (VIII), beta-daucosterin (IX). CONCLUSION: Among the nine isolated compounds, compounds I, II, III, IV, V, are flavonoids. Compounds I , IV, V, VII, VIII, IX are isolated from this plant for the first time.