Synthesis and functionalities of FeSn12 superatom prepared by single atom introduction with a dendrimer template.

Superatoms are promising as new building block materials that can be designed by precise controlling of the constituent atoms. Stannaspherene (Sn12 2-) is a rigid cage-like cluster with icosahedral symmetry, for which one-atom encapsulation was theoretically expected and detected in the gas phase. Here, a single-atom introduction method into stannaspherene using a dendrimer template with polyvinylpyrrolidone (PVP) protection is demonstrated. This advanced solution-phase synthesis allows not only the selective doping of one atom into the cluster cage, but also enable further detail characterization of optical and magnetic properties that were not possible in the gas-phase synthesis. In other words, this liquid-phase synthesis method has enabled the adaptation of detailed analytical methods. In this study, FeSn12 was synthesized and characterized, revealing that a single Fe atom introduction in the Sn12 2- cage result in the appearance of near-infrared emission and enhancement in the magnetism.

Variations in subtle cystic tumors of the atrioventricular node: Five autopsy cases.

Cystic tumor of the atrioventricular node (CTAVN) is the most common primary cardiac tumor cause of sudden death but is rarely found during forensic autopsy. We present five autopsy cases of sudden death from undiagnosed CTAVN. The tumors varied in their histological appearance, which may be related to their variation in clinical presentation. Some of the cases had been diagnosed with epilepsy before death; it seems that syncopal attacks caused by CTAVN may be misdiagnosed as epilepsy. When performing forensic autopsy, CTAVN should be considered in the differential diagnosis of sudden death. Careful examination of the cardiac conduction system is important in every sudden death case regardless of age.

Causes of death of forensic autopsy cases tested positive for COVID-19 in Tokyo Metropolis, Japan.

BACKGROUND: The profile of deaths related to coronavirus disease of 2019 (COVID-19) that occurred outside the hospital in Japan remains unclear because of cautious stance on performing autopsies of COVID-19 positive cases. METHODS: Autopsy cases that tested positive for COVID-19 in the Tokyo Metropolis from April 2020 to July 2022 were handled by medical examiners (n = 41). Age, sex, medical history, autopsy findings, cause of death, postmortem computed tomography (PMCT) findings, and the causal relationship between death and COVID-19 were examined. RESULTS: The mean age of the deceased was 58.0 years (range: 28-96 years), and the study sample consisted of 33 males (80.5%) and 8 females (19.5%). The most frequent medical histories were hypertension (n = 7) and diabetes (n = 7), followed by mental disorders (n = 5). Nineteen cases showed a body mass index ≧25.0 (46.3%). The leading cause of death was pneumonia (n = 17), in which diffuse ground-glass opacification and/or consolidation was noted on PMCT. There were 26 deaths directly related to COVID-19 (63.4%), including pneumonia, myocarditis, laryngotracheobronchitis, and emaciation. The proportion of deaths directly related to COVID-19 was lower after 2022 (42.1%) than prior to 2022 (81.8%). CONCLUSION: Pneumonia was the leading cause of death in this study sample; however, the causes of death in COVID-19 positive cases varied, especially after 2022, when the omicron variant was dominant. Mortality statistics may be affected by viral mutations, and the results of this study further emphasize the need for autopsy because more differential diagnoses should be considered in the phase of the omicron variant.

Comparison of lithium levels between suicide and non-suicide fatalities: Cross-sectional study.

Ecological studies have suggested the protective effect of micro-dose lithium in drinking water against suicide, however, the association between body lithium level and suicide is unknown. We aimed to compare body lithium levels between suicide and non-suicide fatalities. This cross-sectional study included 12 suicides and 16 non-suicides who were examined or dissected at the Tokyo Medical Examiner's Office from March 2018 to June 2021. The aqueous humor lithium concentration was measured twice using inductively coupled plasma mass spectrometry. Analysis of covariance (ANCOVA) was used to compare the lithium concentration between suicides and non-suicides. Mixed-effects model was conducted to account for all lithium concentration data. The aqueous humor lithium concentration did not change after death (t(7) = -0.70, [Formula: see text], SE = 0.03, 95% CI = [-0.09, 0.05], P = 0.51, Cohen's d = 0.01). The aqueous humor lithium concentration was lower in suicides (mean 0.50 µg/L (variance s2 0.04)) than in non-suicides (mean 0.92 µg/L (s2 0.07)) (t(26) = 4.47, [Formula: see text], SE = 0.09, 95% CI = [0.22 to 0.61], P < 0.001, Cohen's d = 1.71). The ANCOVA showed that death by suicide was significantly associated with lower lithium concentration (F(1, 24) = 8.57, P = 0.007), and the effect size was large (ηp2 = 0.26). The random intercept model showed a significant effect of suicide on aqueous humor lithium concentration (b = -0.261, SE = 0.102, 95% CI = [-0.471 to -0.051], t(24) = -2.568, P = 0.017). The results of this study demonstrate that even micro-dose lithium is associated with suicide death. Clinical studies are warranted to examine the effects of micro-dose lithium on suicide prevention.

Controlled Synthesis of Au25 Superatom Using a Dendrimer Template.

Superatoms are promising materials for their potential in elemental substitution and as new building blocks. Thus far, various synthesis methods of thiol-protected Au clusters including an Au25 superatom have been investigated. However, previously reported methods were mainly depending on the thermodynamic stability of the aimed clusters. In this report, a synthesis method for thiol-protected Au clusters using a dendrimers template is proposed. In this method, the number of Au atoms was controlled by the stepwise complexation feature of a phenylazomethine dendrimer. Therefore, synthesis speed was increased compared with the case without the dendrimer template. Hybridization for the Au25 superatoms was also achieved using the complexation control of metals.

A useful preparation of ultrasmall iron oxide particles by using arc plasma deposition.

Ultrasmall particles, different from the larger size nanoparticles, have recently attracted significant attention in the scientific community in nanotechnology for catalytic, electronic and optical applications; however, their magnetic properties remain unexplored due to the difficult structural analysis. A challenging issue is to develop a preparation method for iron oxide particles (IOPs) with fine size control, and to determine the dependence of magnetic properties on the morphology and crystallinity of the magnetic particles. However, synthetic approaches to obtain IOPs, regarded as one of the new fields of magnetic nanoparticles, have been significantly limited. This article reported a developed synthetic method to prepare IOPs on carbon supports using pulsed arc plasma deposition (APD) in flowing oxygen gas, which clarified the finely-controlled formation of IOPs on graphene nanosheets. Structural characterization of the IOPs revealed the formation of crystalline γ-Fe2O3 ultrasmall particles with oxygen deficiency. The pulsed APD method for IOPs is the first simple and convenient technique to not only prevent significant aggregation and contamination by organic compounds and avoid the need for thermal pretreatment, but also provide uniform crystalline nano-order particles.

Severe Cardiac Rupture by Only One Blow to the Chest in a Young Boy: An Autopsy Case.

Cardiac rupture by blunt chest trauma is commonly seen after motor vehicle accidents and falls; however, it is rarely caused by a blow to the chest. We herein report an autopsy case of a high school boy who sustained severe right ventricular rupture by only one knee kick to the chest during a quarrel. He was hospitalized and developed cardiopulmonary arrest. Emergency surgery was performed, but the patient died. The autopsy revealed no external severe trauma or deformation, but the side wall of the right ventricle contained a large V-shaped laceration. The other thoracic organs had no injuries. This case illustrates that severe cardiac rupture can occur by only one blow to the chest. Blunt cardiac injuries can occur even if no severe injuries are present on the body surface. We should consider the possibility of severe cardiac injuries regardless of the presence of external injuries.