[Normative and legal aspects of medical support of the persons working with toxic chemicals relating to the chemical weapons].

In article the existing lows and other legislation acts of state regulation in the field of medical maintenance of the works connected to destruction of toxic chemicals concerning to the chemical weapon is analysed. Features of carrying out of medical examinations and expertise of diseases at the soldiers and officers occupied on these works are submitted. The conclusion that the existing legislation acts allows to carry out qualitative medical service of the personnel of objects of storage and destruction of the chemical weapon, the military men occupied on works with toxic chemicals and the inhabitants living in sanitary-protective zones is made.

[Examination of the significance of parameters used to assess the public health status].

The paper analyzes the opinion of experts who determine the significance (weight) of the population's public health indices used for the integrated assessment of human health when sociomonitoring is made. The statistical assessments of the significance of the indices have been determined using the data obtained from the questioning of experts by the developed procedure. Conclusions on the practical use of the results of the performed study have been drawn.

[Methodology of comprehensive evaluation of the population's health during sociohygienic monitoring].

The authors propose the system for evaluating health indices in the population of our country's region, which comprises groups of specific characteristics: demographic; environmental; environment-induced; overall morbidity (including socially induced); and socioeconomic. It has shown that the methods for analyzing a complex of the population's health indices should be aimed at having estimates of the efficiency of solution of practical problems in the maintenance of the population's health at a respective regional level. For their realization, an information analytical system of appropriate use should be developed; moreover, the results of processing the data with its use should be submitted for further analysis at the federal level.

[Experience in comprehensively assessing the health status of the Saint Petersburg population].

A scheme is proposed to calculate the overall human health indices by the values of partial grouped parameters: demographic, environmental, environment-induced, total (including social) morbidity; socioeconomic and preset threshold levels of their qualitative assessment. This method has been used to estimate morbidity rates in 7 Saint Petersburg districts.

[Classification of results of studying blood plasma with laser correlation spectroscopy based on semiotics of preclinical and clinical states]. / Klassifikatsiia rezul'tatov issledovaniia plazmy krovi s pomoshch'iu lazernoi korreliatsionnoi spektroskopii na osnove semiotiki predklinicheskikh i klinicheskikh sostoianii.

The usage of laser correlation spectroscopy for verification of preclinical and clinical states is substantiated. Developed "semiotic" classifier for solving the problems of preclinical and clinical states is presented. The substantiation of biological algorithms as well as the mathematical support and software for the proposed classifier for the data of laser correlation spectroscopy of blood plasma are presented.

[Structure of occupational diseases in patients examined and treated at the Institute clinic of hygiene, occupational diseases and human ecology]. / Struktura professional'nykh zabolevanii u bol'nykh, proshedshikh obsledovanie i lechenie v klinike NII gigieny, profpatologii i ékologii cheloveka.

The authors analyze data on patients diagnosed as having occupational disease in 1970-1995 and grouped according to age, sex, length of service, occupational hazards. Incidence of various syndromes in occupational diseases is calculated. The authors detail some items obscuring diagnosis of occupational diseases and necessitate referral to various professionals for precise and early diagnosis.

[Chemical accidents and organization of medical services]. / Khimicheskie avarii s pozitsii organizatsii meditsinskoi pomoshchi.

Having analyzed 274 accidents, the authors summarize accident definitions and stages of chemical accident, presents parameters of chemical risk, determine chemicals frequently involved into accidents, evaluate occurrence and severity of chemical disorders. The article outlines suggestions on accidents account in this country.

[Psychophysiological changes in occupational diseases of chemical etiology]. / Psikhofiziologicheskie izmeneniia pri professional'nykh zabolevaniiakh khimicheskoi étiologii.

Use of various psychophysiologic methods enabled to specify psychic response of workers exposed to chemicals and chronic poisoning patients. Chronic poisonings with 1,1-dimethylhydrazine, hydrocarbons, Trichlorfon, mercury, nitroesters have specific traits, and the patients could be grouped by means of cluster analysis. Handy techniques evaluating attention and memory could be recommended for everyday practical needs.

[Acute poisoning by neuroparalytic agents and its long-term effects]. / Ostrye otravleniia veshchestvami nervno-paraliticheskogo deistviia i ikh otdalenye posledstviia.

The authors analyzed over 200 cases of acute poisoning with sarin, soman and VX chemical, determined risk of the poisoning in various conditions. The clinical manifestations of acute poisoning and the long-term effects are presented.

[Chronic poisoning by organophosphoric VX]. / Khronicheskie intoksikatsii fosfororganicheskim veshchestvom Vi-Iks.

Long-term observation of workers engaged into production of VX chemical diagnosed slow progressing manifestation of chronic occupational poisoning with the chemical. The characteristic nervous, digestive, locomotory, visual and cardiovascular symptoms were revealed. The authors presented laboratory and instrumental data on the cases. As the treatment appeared ineffective, further adjustment and improvement of the therapy is required. The article demonstrated the main underlying metabolic disorders that could be addressed by the pathogenetic therapy.

[Laser correlational spectroscopy in studying the subfractional composition of the blood plasma of patients with gastric hemorrhage, craniocerebral trauma and intoxication]. / Lazernaia korreliatsionnaia spektroskopiia v issledovanii subfraktsionnogo sostava plazmy krovi bol'nykh s zheludochnym krovotecheniem, cherepno-mozgovoi travmoi i intoksikatsiiami.

LCS presents information on the size distribution of particles in analysed objects. LCS of blood plasma was performed in 26 patients with stomach bleedings, 19 with brain injuries, 13 with chronic hepatitis, 149 with chronic chlorophos intoxication and 45 healthy subjects. Spectra of blood plasma from patients with stomach bleeding differed significantly from those of healthy subjects. Spectra of blood plasma from patients with brain injuries differed from those of alcohol poisoning patients. The size distribution of particles in the blood plasma alcohol poisoning patients was similar to that of the patients with chronic hepatitis or chronic chlorophos intoxication perhaps because of liver function disturbances in all these cases. These results allow LCS to be offered as a diagnostic method.

[Interdisciplinary organization of scientific studies in the field of the evaluation of environment]. / Mezhdistsiplinarnaia organizatsiia nauchnykh issledovanii v oblasti otsenki okruzhaiushchei sredy.

The structure of Scientific Research Institute of Hygiene and Occupational Health includes the attributes of integrated principles installed by S.D. Zaugolnikov in 60-70s and conforms to the tasks of the integrated approach to investigations. The investigations in main fields as toxicology, hygiene and occupational pathology are carried out in conjunction with the auxiliary subdivisions such as laboratories of mathematical and physical modeling, ecology, pathomorphology ets.

[Noninvasive determination of oxyhemoglobin in arterial blood]. / Neinvazivnoe opredelenie oksigemoglobina v arterial'noi krovi.

The authors describe the principles of noninvasive measurements of oxyhemoglobin content in the arterial blood by processing the signals obtained as a result of passing the light waves of the infrared (940 nm) and red (660 nm) wave bands through tissues. The data obtained with the first Russian pulse oximeter and with the hemoximeter were found to coincide. The diagnostic value of oximetry is discussed.

[Method and results of the study of excursion of peripheral arterial (precapillary) walls]. / Metod i rezul'taty issledovaniia ékskursii stenok perifericheskikh arterial'nykh sosudov (prekapilliarov).

A photoelectric method was employed for examining excursion of peripheral arterial vessels (precapillaries) walls in the middle of the first phalanx of the forefinger of man. The magnitude of the mean amplitude of walls excursion was found to be equal to about 18.5 microns. It is concluded that the shape and amplitude of the curve obtained may serve the basis for estimating the tone of the precapillaries, the time of the volume increase/decrease, and the extent of vascular enlargement.

[A case of mass legionellosis infection in an enterprise of the rubber technology industry]. / Sluchai massovogo zabolevaniia legionellezom na predpriiatii rezinotekhnicheskoi promyshlennosti.

On the basis of the analysis of the sanitary and hygienic conditions, epidemiology of a mass disease, clinical picture of the disease during a 6-month trial period the problems of differentiated diagnosis of infectious and toxic processes, examination of capacity for work, the course of diseases were studied in 219 workers who had had legionellosis. The participation of various specialists in the analysis of analogous cases at the enterprises with chemical environmental contamination and developed systems of air conditioning was considered necessary.