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1.
Sci Rep ; 14(1): 15865, 2024 Jul 09.
Artículo en Inglés | MEDLINE | ID: mdl-38982103

RESUMEN

The study of the Kadomtsev-Petviashvili (KP) model is widely used for simulating several scientific phenomena, including the evolution of water wave surfaces, the processes of soliton diffusion, and the electromagnetic field of transmission. In current study, we explore some multiple soliton solutions of the (3+1)-dimensional generalized KP model via applying modified Sardar sub-equation approach (MSSEA). By extracting the novel soliton solutions, we can effectively obtain singular, dark, combo, periodic and plane wave solutions through a multiple physical regions. We also investigate the chaotic structure of governing model using the chaos theory. The behavior of the collected solutions is visually depicted to demonstrate the physical properties of the proposed model. The solutions obtained in this paper can expand the existing solutions of the (3+1)-dimensional KP model and enhance our understanding of the nonlinear dynamic behaviors. This approach allows for consistent and effective treatment of the computation process for nonlinear KP model.

2.
J Health Organ Manag ; 38(5): 724-740, 2024 Jul 16.
Artículo en Inglés | MEDLINE | ID: mdl-39008095

RESUMEN

PURPOSE: This study aims to explore the adverse impacts of abusive supervision on helping behaviors among employees, as mediating by intention to leave and moderating by Islamic work ethics (IWE). DESIGN/METHODOLOGY/APPROACH: A quantitative approach was employed, and the sample consisted of 283 nurses working in various public sector hospitals in Pakistan. The data analysis was conducted using SPSS and AMOS with the PROCESS macro. FINDINGS: The results suggest that abusive supervision diminishes helping behavior among nurses. Additionally, the study reveals that intention to leave mediates the relationship of abusive supervision and nurses' helping behavior. Moreover, the introduction of IWE as a boundary condition reveals that the mediated link is weaker when IWE is higher, and vice versa. PRACTICAL IMPLICATIONS: This study provides valuable insights for hospital authorities to develop intervention strategies and policies aimed at reducing abusive supervision in hospitals. Hospital management should also be aware of the detrimental effects of abusive supervision on nurses' helping behaviors, which can be mitigated by promoting ethical values aligned with IWE. ORIGINALITY/VALUE: This study makes a valuable contribution to the limited research on the link between abusive supervision and helping behaviors in hospital settings. It offers new perspectives by incorporating the Conservation of Resources theory, particularly within the healthcare sector. Furthermore, this research expands the current knowledge by investigating the mediating influence of intention to leave and the moderating effect of IWE in mitigating the adverse impact of abusive supervision on nurses' helping behavior in Pakistan's public sector hospitals.


Asunto(s)
Conducta de Ayuda , Personal de Enfermería en Hospital , Humanos , Pakistán , Femenino , Adulto , Personal de Enfermería en Hospital/psicología , Masculino , Encuestas y Cuestionarios , Hospitales Públicos
3.
J Pak Med Assoc ; 74(7): 1240-1244, 2024 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-39028047

RESUMEN

Objectives: To determine the response of various histological types of locally advanced rectal cancer to neoadjuvant multimodality therapy. METHODS: The non-randomised, quasi-experimental retrospective cohort study was conducted at the Combined Military Hospital, Rawalpindi, Pakistan, and comprised data of patients treated between January 1, 2020, to September 30, 2021. The data retrieved related to histologically proven and locally advanced rectal cancer patients aged 18-70 years receiving neoadjuvant chemoradiotherapy. Radiotherapy dose was 45 gray to pelvis with a boost to gross tumour of 5.4 gray in 3 fractions by using volumetric arc therapy concurrently with capecitabine 625mg/m² daily. A magnetic resonance imaging scan of pelvis with contrast was done at 5-10 weeks before surgery. Histological response to neoadjuvant treatment of various histological types was evaluated using the Rectal Cancer Regression Grade. Data was analysed using SPSS 22. RESULTS: Of the 182 patients evaluated, 108(59.34%) were included; 64(59.3%) males and 44(40.7%) females. The overall mean age was 45.4±5.2 years. Regression status was grade 1 in 24(22%) patients, grade 2 in 43(40%) and grade 3 in 41(38%) (p=0.074). There were 12(11.11%) patients with signet ring cell and 10(83.3%) showed pathological tumour regression. There were 17(15.74%) patients with mucinous variant, and 12(70.5%) had tumour regression. There were 79(73.15%) patients with adenocarcinoma, and 59(74.6%) of them showed tumour regression. . CONCLUSIONS: There was less tumour regression in mucinous and signet ring cell variants of adenocarcinoma. Modification and intensification of neoadjuvant therapy may be required in such histologies.


Asunto(s)
Adenocarcinoma , Capecitabina , Terapia Neoadyuvante , Neoplasias del Recto , Humanos , Neoplasias del Recto/terapia , Neoplasias del Recto/patología , Neoplasias del Recto/diagnóstico por imagen , Persona de Mediana Edad , Masculino , Femenino , Terapia Neoadyuvante/métodos , Adulto , Estudios Retrospectivos , Adenocarcinoma/terapia , Adenocarcinoma/patología , Adenocarcinoma/diagnóstico por imagen , Capecitabina/administración & dosificación , Capecitabina/uso terapéutico , Anciano , Pakistán , Quimioradioterapia Adyuvante , Quimioradioterapia/métodos , Imagen por Resonancia Magnética , Carcinoma de Células en Anillo de Sello/terapia , Carcinoma de Células en Anillo de Sello/patología , Carcinoma de Células en Anillo de Sello/diagnóstico por imagen , Adulto Joven , Adenocarcinoma Mucinoso/terapia , Adenocarcinoma Mucinoso/patología , Adenocarcinoma Mucinoso/diagnóstico por imagen
4.
J Pak Med Assoc ; 74(7): 1364-1366, 2024 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-39028073

RESUMEN

Radial neck fractures with radial head rotation are very rare and extremely difficult to manage. We present the case of an 11-year-old girl who fell on her outstretched left upper extremity and damaged her left elbow in a road traffic accident. An arthrotomy was performed under a C-Arm fluoroscope, which confirmed the radial head displacement of 180° along with the fracture. The fracture site was reduced and fixed with two Kirschner wires, cutting the wire short at its distal end for a complete closure. Open reduction and internal fixation were followed by casting for five weeks. After two years of follow-up, she had complete pain free range of motion of the affected limb. No post-operative complications have been observed till date. Open reduction and internal fixation with two Kwires is a viable option for such complex injuries. However, further evaluation of outcomes and post-operative complications are required.


Asunto(s)
Fijación Interna de Fracturas , Fracturas del Radio , Humanos , Femenino , Fracturas del Radio/cirugía , Fracturas del Radio/diagnóstico por imagen , Niño , Fijación Interna de Fracturas/métodos , Hilos Ortopédicos , Lesiones de Codo , Rango del Movimiento Articular , Accidentes de Tránsito , Reducción Abierta/métodos , Rotación , Articulación del Codo/cirugía , Articulación del Codo/diagnóstico por imagen , Fracturas Radiales de Cabeza y Cuello
5.
Adv Mater ; : e2402503, 2024 Jun 21.
Artículo en Inglés | MEDLINE | ID: mdl-38962884

RESUMEN

Quantum materials, with nontrivial quantum phenomena and mechanisms, promise efficient quantum technologies with enhanced functionalities. Quantum technology is held back because a gap between fundamental science and its implementation is not fully understood yet. In order to capitalize the quantum advantage, a new perspective is required to figure out and close this gap. In this review, spin gapless quantum materials, featured by fully spin-polarized bands and the electron/hole transport, are discussed from the perspective of fundamental understanding and device applications. Spin gapless quantum materials can be simulated by minimal two-band models and could help to understand band structure engineering in various topological quantum materials discovered so far. It is explicitly highlighted that various types of spin gapless band dispersion are fundamental ingredients to understand quantum anomalous Hall effect. Based on conventional transport in the bulk and topological transport on the boundaries, various spintronic device aspects of spin gapless quantum materials as well as their advantages in different models for topological field effect transistors are reviewed.

6.
PLoS One ; 19(6): e0304871, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38905310

RESUMEN

This study suggests a strategy for calculating the fuzzy analytical solutions to a two-dimensional fuzzy fractional-order heat problem including a diffusion variable connected externally. We propose Sawi residual power series scheme (SRPSS) which is the amalgamation of Sawi transform and residual power series scheme under the Caputo fractional differential operator. We demonstrate three different examples to derive the fuzzy fractional series solution which is characterized by its rapid convergence and easy finding of the unknown coefficients using the concept of limit at infinity. The most significant aspect of this scheme is that it derives the results without time effort compared with the traditional residual power series approach. Our findings confirm that the SRPSS is a robust and valuable method for approximating the solution of fuzzy fractional problems. Furthermore, we provide 2D and 3D symbolic representations to present the physical behavior of fuzzy fractional problems under the lower and upper bounded solutions.


Asunto(s)
Lógica Difusa , Calor , Algoritmos , Modelos Teóricos
7.
PLoS One ; 19(6): e0302520, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38857234

RESUMEN

This paper introduces a refined approach for obtaining the analytical solution of the nonlinear shock wave model incorporating fractal derivatives. The Fractal Yang Variational Iteration Strategy (FYVIS) is utilized to obtain the approximate solution of a fractal model in the form of a series under Caputo fractional operator. The suggested method is the composition of the fractal Yang transform and the variational iteration approach. By using the two-scale fractal theory, we transform the fractal model into its traditional problem and then apply the yang transform to generate a recurrence relation. The variational iteration approach is now suitable to handle this recurrence relation without imposing any hypotheses or restrictions on variables. The derived results by the proposed scheme are shown in terms of series solution. Numerical calculations verify the accuracy and consistency of the suggested approach, demonstrating its excellent performance. The dynamic behavior of fractal components is explored by evaluating absolute errors and presenting two-dimensional diagrams across the fractal domain. This investigation underscores that the suggested technique offers an efficient and user-friendly solution for solving the nonlinear shock wave model involving fractal derivatives.


Asunto(s)
Algoritmos , Fractales , Dinámicas no Lineales , Modelos Teóricos , Simulación por Computador
8.
Sci Rep ; 14(1): 12641, 2024 06 02.
Artículo en Inglés | MEDLINE | ID: mdl-38825663

RESUMEN

In many countries with wastewater irrigation and intensive use of fertilizers (minerals and organics), heavy metal deposition by crops is regarded as a major environmental concern. A study was conducted to determine the impact of mineral fertilizers, cow manure, poultry manure, leaf litter, and sugarcane bagasse on soil's trace Pb content and edible parts of vegetables. It also evaluated the risk of lead (Pb) contamination in water, soil, and food crops. Six vegetables (Daucus carota, Brassica oleracea, Pisum sativum, Solanum tuberosum, Raphanus sativus, and Spinacia oleracea) were grown in the field under twelve treatments with different nutrient and water inputs. The lead concentrations in soil, vegetables for all treatments and water samples ranged from 1.038-10.478, 0.09346-9.0639 mg/kg and 0.036-0.26448 mg/L, The concentration of lead in soil treated with wastewater in treatment (T6) and vegetable samples was significantly higher, exceeding the WHO's permitted limit. Mineral and organic fertilizers combined with wastewater treatment reduced lead (Pb) concentrations in vegetables compared to wastewater application without organic fertilizers. Health risk indexes for all treatments except wastewater treatment (T6) were less than one. Pb concentrations in mineral fertilizers, cow manure, poultry manure, leaf litter, and sugarcane bagasse treated were determined to pose no possible risk to consumers.


Asunto(s)
Fertilizantes , Plomo , Estiércol , Verduras , Aguas Residuales , Fertilizantes/análisis , Verduras/metabolismo , Verduras/química , Estiércol/análisis , Aguas Residuales/química , Aguas Residuales/análisis , Plomo/análisis , Plomo/metabolismo , Animales , Contaminantes del Suelo/análisis , Suelo/química , Bovinos , Productos Agrícolas/metabolismo , Productos Agrícolas/crecimiento & desarrollo , Productos Agrícolas/química , Minerales/análisis
9.
Food Sci Nutr ; 12(6): 3787-3805, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38873476

RESUMEN

This review covers the significance of green banana resistant starch (RS), a substantial polysaccharide. The food industry has taken an interest in green banana flour due to its 30% availability of resistant starch and its approximately 70% starch content on a dry basis, making its use suitable for food formulations where starch serves as the base. A variety of processing techniques, such as heat-moisture, autoclaving, microwaving, high hydrostatic pressure, extrusion, ultrasound, acid hydrolysis, and enzymatic debranching treatments, have made significant advancements in the preparation of resistant starch. These advancements aim to change the structure, techno-functionality, and subsequently the physiological functions of the resistant starch. Green bananas make up the highest RS as compared to other foods and cereals. Many food processing industries and cuisines now have a positive awareness due to the functional characteristics of green bananas, such as their pasting, thermal, gelatinization, foaming, and textural characteristics. It is also found useful for controlling the rates of cancer, obesity, and diabetic disorders. Moreover, the use of GBRS as prebiotics and probiotics might be significantly proved good for gut health. This study aimed at the awareness of the composition, extraction and application of the green banana resistant starch in the future food products.

10.
Dalton Trans ; 53(26): 10875-10889, 2024 Jul 02.
Artículo en Inglés | MEDLINE | ID: mdl-38874545

RESUMEN

Electrocatalytic hydrogen generation in alkaline medium has become widely used in a variety of sectors. However, the possibility for additional performance improvement is hampered by slow kinetics. Because of this restriction, careful control over processes such as water dissociation, hydroxyl desorption and hydrogen recombination is required. Covalent organic frameworks (COFs) based on porphyrin and polyoxometalates (POMs) show encouraging electrocatalytic performance, offering a viable route for effective and sustainable hydrogen generation. Their specific architectures lead to increased electrocatalytic activity, which makes them excellent choices for developing water electrolysis as a clean energy conversion method in the alkaline medium. In this regard, TTris@ZnPor and Lindqvist POM were coordinated to create a new eco-friendly and highly active covalent organic framework (TP@VL-COF). In order to describe TP@VL-COF, extensive structural and morphological investigations were carried out through FTIR, 1H NMR, elemental analysis, SEM, fluorescence, UV-visible, PXRD, CV, N2-adsorption isotherm, TGA and DSC analyses. In an alkaline medium, the electrocatalytic capability of 20%C/Pt, TTris@ZnPor, Lindqvist POM and TP@VL-COF was explored and compared for the hydrogen evolution reaction (HER). The TP@VL-COF showed the best catalytic efficiency for HER in an alkaline electrolyte, requiring just a 75 mV overpotential to drive 10 mA cm-2 and outperforming 20%C/Pt, TTris@ZnPor, Lindqvist POM and other reported catalysts. The Tafel slope value also indicates faster kinetics for TP@VL-COF (114 mV dec-1) than for 20%C/Pt (182 mV dec-1) TTris@ZnPor (116 mV dec-1) and Lindqvist POM (125 mV dec-1).

11.
Sci Rep ; 14(1): 11705, 2024 05 22.
Artículo en Inglés | MEDLINE | ID: mdl-38778064

RESUMEN

A serious environmental problem that threatens soil quality, agricultural productivity, and food safety is heavy metal pollution in water sources. Heavy metal pollution is the main problem in tehsil Pasrur, Sialkot, Pakistan. Present study was arranged to notice the heavy metals in water, soil, forages and buffalo milk. There are seven sites that were used for this experiment. Highest malondialdehyde (MDA) contents (3.00 ± 0.01) were noticed in barseem roots at site 7. Ascorbate Peroxidase (APX) was reached at its peak (1.93 ± 0.01) at site 7 in the fresh barseem. Maximum protein contents (0.36 ± 0.01) were observed in fresh plant samples at site 2. Site 3's buffalo milk samples had the highest Ni content (7.22 ± 0.33 ppm), while Site 3's soil samples had the lowest Cr content (8.89 ± 0.56 ppm), Site 1's plant shoots had the lowest Cr content (27.75 ± 1.98 ppm), and Site 3's water had the highest Cr content (40.07 ± 0.49 ppm). The maximum fat content (5.38 ± 2.32%) was found in the milk of the animals at site 7. The highest density (31.88 ± 6.501%), protein content (3.64 ± 0.33%), lactose content (5.54 ± 0.320%), salt content (0.66 ± 0.1673%), and freezing point (- 0.5814 ± 0.1827 °C) were also observed in the milk from animals at site 7, whereas site 5 displayed the highest water content (0.66 ± 0.1673%) and peak pH value (11.64 ± 0.09). In selected samples, the pollution load index for Ni (which ranged from 0.01 to 1.03 mg/kg) was greater than 1. Site 7 has the highest conductivity value (5.48 ± 0.48). Values for the health risk index varied from 0.000151 to 1.00010 mg/kg, suggesting that eating tainted animal feed may pose health concerns. Significant health concerns arise from metal deposition in the food chain from soil to feed, with nickel having the highest health risk index.


Asunto(s)
Metales Pesados , Leche , Contaminantes del Suelo , Suelo , Animales , Metales Pesados/análisis , Contaminantes del Suelo/análisis , Leche/química , Leche/metabolismo , Pakistán , Suelo/química , Contaminantes Químicos del Agua/análisis , Alimentación Animal/análisis , Búfalos , Monitoreo del Ambiente/métodos , Malondialdehído/metabolismo , Malondialdehído/análisis
12.
Comput Biol Med ; 175: 108529, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38718667

RESUMEN

Many health challenges are attributed to viral infections, which represent significant concerns in public health. Among these infections, diseases such as herpes simplex virus (HSV), cytomegalovirus (CMV), and varicella-zoster virus (VZV) infections have garnered attention due to their prevalence and impact on human health. There are specific antiviral medications available for the treatment of these viral infections. Drugs like Cidofovir, Valacyclovir, and Acyclovir are commonly prescribed. These antiviral drugs are known for their efficacy against herpesviruses and related viral infections, leveraging their ability to inhibit viral DNA polymerase. A molecular descriptor is a numerical value that correlates with specific physicochemical properties of a molecular graph. This article explores the calculation of distance-based topological descriptors, including the Trinajstic, Mostar, Szeged, and PI descriptors for the aforementioned antiviral drugs. These descriptors provide insights into these drugs' structural and physicochemical characteristics, aiding in understanding their mechanism of action and the development of new therapeutic agents.


Asunto(s)
Antivirales , Antivirales/uso terapéutico , Antivirales/química , Antivirales/farmacología , Humanos , Aciclovir/uso terapéutico , Aciclovir/química , Aciclovir/farmacología , Biología Computacional/métodos , Cidofovir/uso terapéutico , Cidofovir/química , Citosina/análogos & derivados , Citosina/uso terapéutico , Citosina/química , Valaciclovir/uso terapéutico
13.
Heliyon ; 10(9): e30429, 2024 May 15.
Artículo en Inglés | MEDLINE | ID: mdl-38737227

RESUMEN

In light of the rapid advancements within the electronic industry, the urgent need for the development and implementation of advanced electromagnetic interference (EMI) shielding materials has become paramount. Herein a novel approach is presented for developing of lightweight honeycomb structures using 3D printing technology, combined with subsequent conductive spray coating, containing Silver Nanowires (AgNWs), to achieve effective EMI shielding as well as air vent functionality for thermal cooling. Using polyol method, AgNWs were synthesized having high aspect ratio and crystallinity for to be used as conductive coating on 3D printed structures. The EMI shielding results in X-band demonstrated that the developed structures exhibit promising EMI shielding properties, up to 35 dB attenuation with 2 mm honeycomb cell size, making them suitable for applications requiring EMI protection along with air venting. More importantly in all samples major contribution of the shielding efficiency comes from the absorption of the EM waves (up to 75 %) inside the structures which is helpful to reduce reflected EM noise. Effort was to effectively addresses the inherent limitations of conventional processing technology, by using additive manufacturing and material science to create structures for EMI shielding applications, bridging the gap between existing materials and desired components.

14.
Data Brief ; 54: 110448, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38725552

RESUMEN

In the current era, satisfying the appetite of data hungry models is becoming an increasingly challenging task. This challenge is particularly magnified in research areas characterised by sensitivity, where the quest for genuine data proves to be elusive. The study of violence serves as a poignant example, entailing ethical considerations and compounded by the scarcity of authentic, real-world data that is predominantly accessible only to law enforcement agencies. Existing datasets in this field often resort to using content from movies or open-source video platforms like YouTube, further emphasising the scarcity of authentic data. To address this, our dataset aims to pioneer a new approach by creating the first synthetic virtual dataset for violence detection, named the Weapon Violence Dataset (WVD). The dataset is generated by creating virtual violence scenarios inside the photo-realistic video game namely: Grand Theft Auto-V (GTA-V). This dataset includes carefully selected video clips of person-to-person fights captured from a frontal view, featuring various weapons-both hot and cold across different times of the day. Specifically, WVD contains three categories: Hot violence and Cold violence (representing the violence category) as well as No violence (constituting the control class). The dataset is designed and created in a way that will enable the research community to train deep models on such synthetic data with the ability to increase the data corpus if the needs arise. The dataset is publicly available on Kaggle and comprises normal RGB and optic flow videos.

15.
Food Sci Nutr ; 12(5): 3508-3515, 2024 May.
Artículo en Inglés | MEDLINE | ID: mdl-38726400

RESUMEN

Rasmalai is a very popular, delicious, and nutritious indigenous sweet dish in Indo-Pakistani civilization. It has a very short shelf life, i.e., up to 3 days. The study was designed to assess the effect of preservatives (potassium sorbate and calcium propionate) on the shelf stability of Rasmalai. Moreover, proximate composition and sensory evaluation of prepared Rasmalai were also carried out in the present study. In general, potassium sorbate and calcium propionate significantly increased the shelf life of Rasmalai. But treatment (R5) containing a combination of both potassium sorbate and calcium propionate (500 ppm each) improved its shelf life by up to 12 days by keeping good sensorial characteristics. The maximum total plate counts as well as yeast and molds were observed in control Rasmalai (without any preservatives) whereas minimum counts were found in R5 treatment containing a combination of both potassium sorbate and calcium propionate (500 ppm each). In conclusion, all the preservatives used in the present study were effective in enhancing the shelf life of Rasmalai but R5 treatment containing a combination of both potassium sorbate and calcium propionate (500 ppm each) was the most effective in enhancing shelf life without deleterious effect on sensorial characteristics.

16.
BMC Plant Biol ; 24(1): 378, 2024 May 09.
Artículo en Inglés | MEDLINE | ID: mdl-38724893

RESUMEN

Pakistan's economy greatly benefits from citrus production since these fruits are sold and consumed all over the world. Although citrus fruits are easy to cultivate, they are susceptible to diseases caused by bacteria, viruses, and fungi. These challenges, as well as difficulties in obtaining the proper nutrients, might negatively impact fruit yields and quality. Citrus canker is another complicated problem caused by the germ Xanthomonas axonopodis. This germ affects many types of citrus fruits all over the world. This study looked closely at how citrus canker affects the leaves and the quality of the fruit in places like Sargodha, Bhalwal, Kotmomin, and Silanwali, which are big areas for growing citrus in the Sargodha district. What we found was that plants without the disease had more chlorophyll in their leaves compared to the sick plants. Also, the healthy plants had better amounts of important minerals like calcium, magnesium, potassium, and phosphorus in their fruits. But the fruits with the disease had too much sodium, and the iron levels were a bit different. The fruits with the disease also didn't have as much of something that protects them called antioxidants, which made them more likely to get sick. This study helps us understand how citrus canker affects plants and fruit, so we can think of ways to deal with it.


Asunto(s)
Citrus , Frutas , Enfermedades de las Plantas , Hojas de la Planta , Xanthomonas axonopodis , Citrus/microbiología , Xanthomonas axonopodis/fisiología , Hojas de la Planta/microbiología , Hojas de la Planta/metabolismo , Enfermedades de las Plantas/microbiología , Frutas/microbiología , Minerales/metabolismo , Minerales/análisis , Clorofila/metabolismo , Pakistán
17.
BMC Med Educ ; 24(1): 495, 2024 May 03.
Artículo en Inglés | MEDLINE | ID: mdl-38702657

RESUMEN

BACKGROUND: The pursuit of medical and dental education is challenging and can affect the overall quality of life of medical students. Assessing the quality of life of medical students is the first step in the preparation of efficient future health care professionals. This study used the World Health Organization Quality of Life Brief Version (WHOQOL-BREF) to evaluate the quality of life of medical and dental students in Karachi, Pakistan. OBJECTIVES: The study objectives include: assessing the QoL of medical and dental students and their general health satisfaction and self-satisfaction. MATERIALS AND METHODS: This cross-sectional study was conducted among 344 medical and dental students from different medical and dental schools in Karachi, Pakistan. The World Health Organization Quality of Life Brief Version (WHOQOL-BREF) questionnaire was used to assess QOL, which included 26 items covering four domains: physical, psychological, social, and environmental. All scores for the domains ranged from 4 to 20. Scoring was done according to the WHOQOL-BREF procedure manual. The questionnaire was disseminated to medical students using Google Forms. SPSS software was used to analyze the data. Cronbach's alpha and the Kaiser-Meyer-Olkin (KMO) test were used to evaluate the reliability and sampling adequacy of the data for factor analysis. Descriptive statistics were computed for each variable and QoL domain, including frequencies, percentages, averages, and standard deviations. Domain scores were compared using a t-test and one-way ANOVA, with p-values less than 0.05, indicating statistical significance. RESULTS: Among the 344 medical students, 56.7% (n = 195) were female and 43.3% (n = 149) were male. The WHOQOL-BREF demonstrated excellent reliability, with a Cronbach's alpha of 0.918. Most medical students rated their overall QOL (62.2%) and health satisfaction (46.8%) as good, and were able to get around well (71.3%). No significant sex differences were found across the various QOL domains. Marital status significantly affected QOL scores (p < 0.005). Single students had significantly higher QOL scores than married/separated/divorced students did. Overall, the environmental domain had the highest mean score (26.81 ± 6.17), while social relationships had the lowest mean score (9.68 ± 2.93). CONCLUSION: The findings of this study provide valuable insights into the QoL of medical and dental students. Most participants reported moderate satisfaction with their physical health and lower satisfaction with the psychological, social, and environmental components of QoL. Marital status was found to significantly impact the QoL as compared to single students with greater QoL. These findings can help form targeted interventions to enhance medical students' quality of life and prepare efficient future healthcare professionals.


Asunto(s)
Calidad de Vida , Estudiantes de Odontología , Estudiantes de Medicina , Humanos , Pakistán , Estudiantes de Medicina/psicología , Estudios Transversales , Masculino , Femenino , Encuestas y Cuestionarios , Estudiantes de Odontología/psicología , Adulto Joven , Satisfacción Personal , Adulto , Reproducibilidad de los Resultados
18.
Sci Rep ; 14(1): 12503, 2024 May 31.
Artículo en Inglés | MEDLINE | ID: mdl-38822062

RESUMEN

This work presents the analytical study of one dimensional time-fractional nonlinear Schrödinger equation arising in quantum mechanics. In present research, we establish an idea of the Sumudu transform residual power series method (ST-RPSM) to generate the numerical solution of nonlinear Schrödinger models with the fractional derivatives. The proposed idea is the composition of Sumudu transform (ST) and the residual power series method (RPSM). The fractional derivatives are taken in Caputo sense. The proposed technique is unique since it requires no assumptions or variable constraints. The ST-RPSM obtains its results through a series of successive iterations, and the resulting form rapidly converges to the exact solution. The results obtained via ST-RPSM show that this scheme is authentic, effective, and simple for nonlinear fractional models. Some graphical structures are displayed at different levels of fractional orders using Mathematica Software.

19.
J Multidiscip Healthc ; 17: 2475-2487, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38799016

RESUMEN

Background: Access to safe drinking water, sanitation, and hygiene (WASH) facilities is crucial for health and human rights, impacting nutrition and weight. Methods: Multiple Indicators Cluster Survey (MICS) 2017-18 has been used in this study to examine the association between WASH and underweight, alongside other factors. Analysis included descriptive statistics, association tests, logistic regression, and population-attributable fractions (PAF). Results: According to results child were 1.8, 1.1 and 1.04 times less likely to be underweight if they had access to improved source of drinking water, improved sanitation and hygiene facilities respectively. The likelihood of child being underweight reduces by 1.4, 1.89, 2.01 and 2.55 times if the household wealth status increases from poorest to second, middle, fourth and richest wealth quintiles, respectively. As the mothers' education level increases from no schooling to primary, middle, secondary, and higher level, the possibility of child being underweight reduces by 1.22, 1.24, 1.60 and 2.01 times, respectively. Moreover, the likelihood of a child being underweight decreases as the education level of the household head improves. If maternal age is less than 20 or more than 35 years the likelihood of the child being underweight is increased by 1.074 and 1.121 times, respectively. A child is 1.1 times more likely to be underweight if birth spacing is less than 2 years. A child's risk of being underweight decreases by 1.1 times if they have not experienced diarrhea. A child who has never been breastfed has 1.3 times higher risk of being underweight. The results of Population Attributable Fraction (PAF) indicate that holding the other factors constant, approximately 36.46% burden of underweight was preventable by access to improved drinking water, sanitation, and hygiene practices. Conclusion: Comprehensive strategy is needed that focuses on improving access to safe drinking water, sanitation infrastructure, and hygiene behaviors.

20.
Environ Sci Process Impacts ; 26(5): 832-842, 2024 May 22.
Artículo en Inglés | MEDLINE | ID: mdl-38619070

RESUMEN

Soil and terrestrial contamination with microplastics and nanoplastics has been discussed extensively, while tire wear particles (TWPs) have been largely overlooked. We investigated the root-surface interactions and growth response of mung bean (Vigna radiata L.) plants exposed to tire wear particles (TWPs) (0.05, 0.1, and 0.25% w/w) and nickel sulfate (50 and 100 mg kg-1 NiSO4) alone and in co-exposure scenarios for the full life cycle (105 days) under soil conditions. The results show that TWPs adhered to the root surface and reduced the water and nutrient uptake by the plant, particularly at higher concentrations of TWPs (0.25% w/w), without any observed organic contaminant accumulation in the root tissue. TWPs alone at 0.01, 0.1, and 0.25% (w/w) decreased mung bean yield by 11, 28, and 52%, respectively. Co-exposure to TWPs at 0.01, 0.1 and 0.25% w/w with 100 mg kg-1 NiSO4 decreased yield by 73, 79 and 88%, respectively. However, co-exposure to TWPs at 0.01 and 0.1% w/w with 50 mg kg-1 NiSO4 enhanced the yield by 32% and 7%, respectively. These changes in yield and nutritional aspects appear to be linked to Ni's regulatory influence on mineral homeostasis. Moreover, exposure to NiSO4 at 100 mg kg-1 increased Ni uptake in the root, shoot, and grain by 9, 26, and 20-fold, respectively as compared to the unamended control; this corresponded to increased antioxidant enzyme activity (10-127%) as compared to the control. TWPs caused blockages, significantly reducing plant yield and altering nutrient dynamics, highlighting emerging risks to plant health.


Asunto(s)
Níquel , Contaminantes del Suelo , Vigna , Vigna/crecimiento & desarrollo , Vigna/metabolismo , Vigna/efectos de los fármacos , Contaminantes del Suelo/metabolismo , Nutrientes/metabolismo , Raíces de Plantas/metabolismo , Raíces de Plantas/crecimiento & desarrollo , Suelo/química
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